Metabolic recycling of storage lipids promotes squalene biosynthesis in yeast

Autor: So-Hee Son, Jae-Eung Kim, Soo Young Moon, In-Seung Jang, Byung Jo Yu, Ju Young Lee

Publikováno v: Biotechnology for Biofuels and Bioproducts, Vol 15, Iss 1, Pp 1-11 (2022)

Abstract Background Metabolic rewiring in microbes is an economical and sustainable strategy for synthesizing valuable natural terpenes. Terpenes are the largest class of nature-derived specialized metabolites, and many have valuable pharmaceutical o

Externí odkaz: https://doaj.org/article/362cca64b78e45f7bbfe25d4656374c9

Improving the efficiency of homologous recombination by chemical and biological approaches in Yarrowia lipolytica.

Autor: In-Seung Jang, Byung Jo Yu, Ji Yeon Jang, Jonggeon Jegal, Ju Young Lee

Publikováno v: PLoS ONE, Vol 13, Iss 3, p e0194954 (2018)

Gene targeting is a challenge in Yarrowia lipolytica (Y. lipolytica) where non-homologous end-joining (NHEJ) is predominant over homologous recombination (HR). To improve the frequency and efficiency of HR in Y. lipolytica, the ku70 gene responsible

Externí odkaz: https://doaj.org/article/54c0bd087369464c9df6bbebec3da392

Enhanced Production of Bacterial Cellulose from Miscanthus as Sustainable Feedstock through Statistical Optimization of Culture Conditions

Autor: Jemin Son, Kang Hyun Lee, Taek Lee, Hyun Soo Kim, Weon Ho Shin, Jong-Min Oh, Sang-Mo Koo, Byung Jo Yu, Hah Young Yoo, Chulhwan Park

Publikováno v: International Journal of Environmental Research and Public Health, Vol 19, Iss 866, p 866 (2022)
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health; Volume 19; Issue 2; Pages: 866

Biorefineries are attracting attention as an alternative to the petroleum industry to reduce carbon emissions and achieve sustainable development. In particular, because forests play an important role in potentially reducing greenhouse gas emissions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa758b21d56dc61694815f60e4a15936
https://www.mdpi.com/1660-4601/19/2/866

Heterologous Production of Squalene from Glucose in Engineered Corynebacterium glutamicum Using Multiplex CRISPR Interference and High-Throughput Fermentation

Autor: Jong-il Choi, Jaehyun Park, Byung Jo Yu, Han Min Woo

Publikováno v: Journal of Agricultural and Food Chemistry. 67:308-319

The sustainable production of squalene has driven the development of microbial cell factories due to the limitation of low-yielding bioprocesses from plants and illegal harvesting shark liver. We report the metabolic engineering of Corynebacterium gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a347ede869efef68a3061aaf27dffa
https://doi.org/10.1021/acs.jafc.8b05818

Effective Cryopreservation of a Bioluminescent Auxotrophic Escherichia coli-Based Amino Acid Array to Enable Long-Term Ready-to-Use Applications

Autor: In Seung Jang, Hyeun Seok Choi, Dong Hoon Lee, Hee Tae Ahn, Byung Jo Yu, Thinh Viet Dang, Yi Hyang Kim, Moon Il Kim

Publikováno v: Biosensors
Biosensors, Vol 11, Iss 252, p 252 (2021)
Volume 11
Issue 8

Amino acid arrays comprising bioluminescent amino acid auxotrophic Escherichia coli are effective systems to quantitatively determine multiple amino acids. However, there is a need to develop a method for convenient long-term preservation of the arra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4a87be0c70402d7bb8579f7846bbcd
https://doi.org/10.3390/bios11080252