Zobrazeno 1 - 10
of 986
pro vyhledávání: '"Byung Chul, Lee"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Polygenic risk score (PRS) and rare monogenic variant screening are valuable tools for predicting cancer risk and identifying individuals at high risk. Integrating both common and rare genetic variants is crucial for accurate risk assessment
Externí odkaz:
https://doaj.org/article/b914003af9a046d3bf9ec260e904e9d6
Autor:
Hyunsoo Kim, Joon-Tae Kim, Ji Sung Lee, Beom Joon Kim, Jihoon Kang, Keon-Joo Lee, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Tai Hwan Park, Kyungbok Lee, Jun Lee, Keun-Sik Hong, Yong-Jin Cho, Hong-Kyun Park, Byung-Chul Lee, Kyung-Ho Yu, Mi Sun Oh, Dong-Eog Kim, Jay Chol Choi, Jee-Hyun Kwon, Wook-Joo Kim, Dong-Ick Shin, Kyu Sun Yum, Sung Il Sohn, Jeong-Ho Hong, Sang-Hwa Lee, Man-Seok Park, Wi-Sun Ryu, Kwang-Yeol Park, Juneyoung Lee, Jeffrey L. Saver, Hee-Joon Bae
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract This study aimed to investigate the association between non-traditional lipid profiles and the risk of 1-year vascular events in patients who were already using statins before stroke and had admission LDL-C
Externí odkaz:
https://doaj.org/article/2340abf3603b4fbe8d42fd82a2305d21
Autor:
Dong-Seok Gwak, Wi-Sun Ryu, Dawid Schellingerhout, Jinyong Chung, Hang-Rai Kim, Sang-Wuk Jeong, Beom Joon Kim, Joon-Tae Kim, Keun-Sik Hong, Jong-Moo Park, Man-Seok Park, Kang-Ho Choi, Tai Hwan Park, Kyungbok Lee, Sang-Soon Park, Kyusik Kang, Yong-Jin Cho, Hong-Kyun Park, Byung-Chul Lee, Kyung-Ho Yu, Mi-Sun Oh, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Jun Lee, Moon-Ku Han, Ji Sung Lee, Hee-Joon Bae, Dong-Eog Kim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract It is uncertain whether the prognostic power of white matter hyperintensity (WMH) on post-stroke outcomes is modulated as a function of initial neurological severity, a critical determinant of outcome after stroke. This multi-center MRI stud
Externí odkaz:
https://doaj.org/article/6cb3df96618c4e2c9344df6c18b7e731
Autor:
Su‐Jeong Oh, Ye Young Shin, Ji‐Su Ahn, Hee‐Jeong Park, Min‐Jung Kang, Tae‐Hoon Shin, Byung‐Chul Lee, Won Kyu Kim, Jung‐Min Oh, Dongjun Lee, Yun Hak Kim, Ji Min Kim, Eui‐Suk Sung, Eun‐Woo Lee, Jee‐Heon Jeong, Byung‐Joo Lee, Yoojin Seo, Hyung‐Sik Kim
Publikováno v:
Advanced Science, Vol 11, Iss 47, Pp n/a-n/a (2024)
Abstract Despite the high incidence of dry mouth in postmenopausal women, its underlying mechanisms and therapeutic interventions remain underexplored. Using ovariectomized (OVX) mouse models, here this study identifies ferroptosis, an iron‐depende
Externí odkaz:
https://doaj.org/article/7ba0b6f787f741d1820472fa17c7037c
Autor:
Dong Jun Kim, Joon Ho Kang, Ji-Woong Kim, Sun bin Kim, Young Kee Lee, Myeong Jae Cheon, Byung-Chul Lee
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
Epigenetic clocks have been developed to track both chronological age and biological age, which is defined by physiological biomarkers and the risk of adverse health outcomes. Epigenetic age acceleration (EAA) has been found to predict various diseas
Externí odkaz:
https://doaj.org/article/afa7399b7958439589f64d3497d6acd9
Autor:
Hyun Sung Park, Byung-Chul Lee, Dong-Hoon Chae, Aaron Yu, Jae Han Park, Jiyoung Heo, Myoung Hee Han, Keonwoo Cho, Joong Won Lee, Ji-Won Jung, Cynthia E. Dunbar, Mi-Kyung Oh, Kyung-Rok Yu
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Mesenchymal stem cells (MSCs) play important roles in tissue homeostasis by providing a supportive microenvironmental niche for the hematopoietic system. Cigarette smoking induces systemic abnormalities, including an impeded recov
Externí odkaz:
https://doaj.org/article/ae7830a8e0ff4921863217e71e9cca06
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract In recent years, the utility of polygenic risk scores (PRS) in forecasting disease susceptibility from genome-wide association studies (GWAS) results has been widely recognised. Yet, these models face limitations due to overfitting and the p
Externí odkaz:
https://doaj.org/article/cae0d85eb66646f4a738e90a5681af75
Autor:
Jeong‐Yoon Lee, Do Yeon Kim, Jun Yup Kim, Jihoon Kang, Beom Joon Kim, Moon‐Ku Han, Yong Soo Kim, Kyusik Kang, Jae Guk Kim, Soo Joo Lee, Dae‐Hyun Kim, Jae‐Kwan Cha, Jin‐Kyo Choi, Sang‐Soon Park, Tai Hwan Park, Kyungbok Lee, Doo Hyuk Kwon, Jun Lee, Hong‐Kyun Park, Yong‐Jin Cho, Keun‐Sik Hong, Minwoo Lee, MI Sun Oh, Kyung‐Ho Yu, Byung‐Chul Lee, Hyunsoo Kim, Kangho Choi, Joon‐Tae Kim, Dong‐Seok Gwak, Dong‐Eog Kim, Chul‐Hoo Kang, Joong‐Goo Kim, Jay Chol Choi, Kyu Sun Yum, Dong‐Ick Shin, Wook‐Joo Kim, Jee‐Hyun Kwon, Hyungjong Park, Jeong‐Ho Hong, Sungil Sohn, Sang‐Hwa Lee, Chulho Kim, Chan‐Young Park, Hae‐Bong Jeong, Kwang‐Yeol Park, Dongwhane Lee, Jong‐Moo Park, Keon‐Joo Lee, Jung Hoon Han, Chi Kyung Kim, Kyungmi Oh, Ho Geol Woo, Sung Hyuk Heo, Jonguk Kim, Juneyoung Lee, Ji Sung Lee, Philip B. Gorelick, Hee‐Joon Bae
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 4, Iss 5 (2024)
Background Perfusion imaging (PI) serves as a valuable tool for triaging patients with acute ischemic stroke for endovascular treatment (EVT). This study aims to investigate trends in PI use and its impacts on EVT rates and clinical outcomes, particu
Externí odkaz:
https://doaj.org/article/92dc098dfaba4d23a159017bafcf0f7d
Autor:
Joon‐Tae Kim, Ji Sung Lee, Hyunsoo Kim, Beom Joon Kim, Keon‐Joo Lee, Jong‐Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae‐Kwan Cha, Dae‐Hyun Kim, Tai Hwan Park, Kyungbok Lee, Jun Lee, Keun‐Sik Hong, Yong‐Jin Cho, Hong‐Kyun Park, Byung‐Chul Lee, Kyung‐Ho Yu, Mi Sun Oh, Dong‐Eog Kim, Jay Chol Choi, Jee‐Hyun Kwon, Wook‐Joo Kim, Dong‐Ick Shin, Kyu Sun Yum, Sung Il Sohn, Jeong‐Ho Hong, Sang‐Hwa Lee, Man‐Seok Park, Wi‐Sun Ryu, Kwang‐Yeol Park, Juneyoung Lee, Jeffrey L. Saver, Hee‐Joon Bae
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 10 (2024)
Background Recent clinical trials established the benefit of dual antiplatelet therapy with aspirin and clopidogrel (DAPT‐AC) in early‐presenting patients with minor ischemic stroke. However, the impact of these trials over time on the use and ou
Externí odkaz:
https://doaj.org/article/cca1701c64834a69a43067ac2a7b9d7c
Autor:
Dong Jun Kim, Joon Ho Kang, Ji-Woong Kim, Myeong Jae Cheon, Sun bin Kim, Young Kee Lee, Byung-Chul Lee
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Polygenic risk scores (PRSs) have been studied for predicting human diseases, and various methods for PRS calculation have been developed. Most PRS studies to date have focused on European ancestry, and the performance of PRS has not been su
Externí odkaz:
https://doaj.org/article/32c1b779c749453eb5a822b1df1331a5