Zobrazeno 1 - 10
of 384
pro vyhledávání: '"Bystander activation"'
Autor:
Christian Niehaus, Sebastian Klein, Benedikt Strunz, Erich Freyer, Benjamin Maasoumy, Heiner Wedemeyer, Niklas K. Björkström, Anke R.M. Kraft, Markus Cornberg
Publikováno v:
JHEP Reports, Vol 6, Iss 6, Pp 101074- (2024)
Background & Aims: Patients with advanced cirrhosis often develop hepatic decompensation, which is accompanied by systemic inflammation and may eventually lead to acute-on-chronic liver failure. One important cause of systemic hyperinflammation is a
Externí odkaz:
https://doaj.org/article/25f9b1d137a244d5b0daaf623a9be220
Publikováno v:
BioImpacts, Vol 13, Iss 4, Pp 269-273 (2023)
Induced autoimmunity or autoinflammatory-like conditions as a rare vaccine-related adverse event have been reported following COVID-19 vaccination. Such inadvertent adverse reactions have raised somewhat concerns about the long-term safety of the dev
Externí odkaz:
https://doaj.org/article/664d713f2795424db39d74204bc65b4b
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 10, Pp n/a-n/a (2024)
Abstract Objectives CD8+ T cells play a critical role in the immune dysfunction associated with liver cirrhosis. CD38+HLA‐DR+CD8+ T cells, or bystander‐activated CD8+ T cells, are involved in tissue injury but their specific contribution to liver
Externí odkaz:
https://doaj.org/article/e2fa5b5950744862b9ae9e9b066844d5
Autor:
Wenbo Yu, Nga TH Truong, Ruhi Polara, Tessa Gargett, Melinda N Tea, Stuart M Pitson, Michaelia P Cockshell, Claudine S Bonder, Lisa M Ebert, Michael P Brown
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Objectives CAR‐T cells are being investigated as a novel immunotherapy for glioblastoma, but clinical success has been limited. We recently described fibroblast activation protein (FAP) as an ideal target antigen for glioblastoma immunothe
Externí odkaz:
https://doaj.org/article/015396e342d8443aa4091f21f509b391
Autor:
Paul Kupke, Johanna Brucker, Jochen M. Wettengel, Ulrike Protzer, Jürgen J. Wenzel, Hans J. Schlitt, Edward K. Geissler, Jens M. Werner
Publikováno v:
Viruses, Vol 16, Iss 5, p 741 (2024)
Hepatitis B virus (HBV) is a major driver of chronic hepatic inflammation, which regularly leads to liver cirrhosis or hepatocellular carcinoma. Immediate innate immune cell response is crucial for the rapid clearance of the infection. Here, natural
Externí odkaz:
https://doaj.org/article/08541a82fe7e490ab7eec775e3bc8885
Akademický článek
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Autor:
Namit Holay, Barry E. Kennedy, J. Patrick Murphy, Prathyusha Konda, Michael Giacomantonio, Tatjana Brauer-Chapin, Joao A. Paulo, Vishnupriyan Kumar, Youra Kim, Mariam Elaghil, Gary Sisson, Derek Clements, Christopher Richardson, Steven P. Gygi, Shashi Gujar
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
CD8 T cells play a central role in antiviral immunity. Type I interferons are among the earliest responders after virus exposure and can cause extensive reprogramming and antigen-independent bystander activation of CD8 T cells. Although bystander act
Externí odkaz:
https://doaj.org/article/43247c5da956443a994817e22e2a9b5e
Autor:
Xiyue Zhang, Yusi Zhang, He Liu, Kang Tang, Chunmei Zhang, Meng Wang, Manling Xue, Xiaozhou Jia, Haifeng Hu, Na Li, Ran Zhuang, Boquan Jin, Fanglin Zhang, Yun Zhang, Ying Ma
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
IntroductionHantaan virus (HTNV) can cause endothelium injury in hemorrhagic fever with renal syndrome (HFRS) patients. Bystander activation of CD8+ T cells by virus infection has been shown that was involved in host injury, but it is unclear during
Externí odkaz:
https://doaj.org/article/6f6d3e7743564529b05fb31e3d21b803
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Resveratrol, a natural product, has demonstrated anti-tumor effects in various kinds of tumor types, including colon, breast, and pancreatic cancers. Most research has focused on the inhibitory effects of resveratrol on tumor cells themselves rather
Externí odkaz:
https://doaj.org/article/8f9b4ef26ebd4b038bb7d1d891f69f64
Akademický článek
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