Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Byron R. Griffith"'
Autor:
Candace J. Krepel, Byron R. Griffith, Aqeel Ahmed, Jon S. Thorson, Charles E. Edmiston, Sophie Blanchard, Xun Fu
Publikováno v:
Journal of the American Chemical Society. 129:8150-8155
The neoglycosylation of a methoxyamine-appended vancomycin aglycon with all possible N'-decanoylglucopyranose and N'-biphenoylglucopyranose regioisomers led to the production of a focused set of liponeoglycopeptide variants in good yields and with ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22416524dad445d3b59557e269d79bcd
https://doi.org/10.1021/ja068602r
https://doi.org/10.1021/ja068602r
Autor:
Changsheng Zhang, John L. Markley, Shanteri Singh, Byron R. Griffith, Min S. Lee, Martin H. Hager, Jon S. Thorson, Klaas Hallenga
Publikováno v:
ACS Chemical Biology. 1:451-460
The recent discovery of the first "self-sacrifice" mechanism for bacterial resistance to the enediyne antitumor antibiotics, where enediyne-induced proteolysis of the resistance protein CalC inactivates both the highly reactive metabolite and the res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff00fa10ed999b63427704f176ff0d6d
https://doi.org/10.1021/cb6002898
https://doi.org/10.1021/cb6002898
Publikováno v:
Current Opinion in Biotechnology. 16:622-630
In an effort to explore the contribution of the sugar constituents of pharmaceutically relevant glycosylated natural products, chemists have developed glycosylation methods for the generation of 'glycorandomized' libraries. Each member of these libra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4f077bd37001b6d99730d023868c5e
https://doi.org/10.1016/j.copbio.2005.10.002
https://doi.org/10.1016/j.copbio.2005.10.002
Autor:
Lingjun Li, Xun Fu, Christoph Albermann, Jon S. Thorson, Qiang Fu, In-Kyoung Lee, Changsheng Zhang, Byron R. Griffith
Publikováno v:
Science (New York, N.Y.). 313(5791)
Glycosyltransferases (GTs), an essential class of ubiquitous enzymes, are generally perceived as unidirectional catalysts. In contrast, we report that four glycosyltransferases from two distinct natural product biosynthetic pathways—calicheamicin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3916beb72ddf03bfb20a45ae53f511
https://pubmed.ncbi.nlm.nih.gov/16946071
https://pubmed.ncbi.nlm.nih.gov/16946071
Publikováno v:
ChemInform. 37
Covering: the literature up to April 2005The focus of this review is to highlight the structure, bioactivity and biosynthesis of naturally occurring aryl-C-glycosides. General synthetic methods and their relevance to proposed biochemical mechanisms f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b17e5ea88d25a6cde6205f0f0db01a
https://doi.org/10.1002/chin.200614260
https://doi.org/10.1002/chin.200614260
Publikováno v:
ChemInform. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af767f24078ea5600e7a4436e946aba3
https://doi.org/10.1002/chin.200607295
https://doi.org/10.1002/chin.200607295
Publikováno v:
Journal of natural products. 68(11)
In an effort to explore the contribution of the sugar constituents of pharmaceutically relevant glycosylated natural products, chemists have developed glycosylation methods that are amenable to the generation of libraries of analogues with a broad ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b520867b6a916812d5f1171cbcbfd96b
https://pubmed.ncbi.nlm.nih.gov/16309329
https://pubmed.ncbi.nlm.nih.gov/16309329
Autor:
Jon S. Thorson, Byron R. Griffith
Publikováno v:
Nature Chemical Biology. 2:659-660
Chemically synthesizing complex oligosaccharides remains a significant challenge. Through the addition of hydrophobic appendages to 'unnatural' substrates, some oligosaccharide-forming glycosyltransferases can direct the formation of distinct sugar l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510251b5e01b87f7110c53f660771bdd
https://doi.org/10.1038/nchembio1206-659
https://doi.org/10.1038/nchembio1206-659
Publikováno v:
Journal of the American Chemical Society. 126:1608-1609
We report the design and synthesis of well-defined polymers for the noncovalent oligomerization of proteins. The reported scaffolds, which were generated by atom-transfer radical polymerization (ATRP), take advantage of the well-characterized interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72678e01b8fee5cc2dc223bd6049ab67
https://doi.org/10.1021/ja037646m
https://doi.org/10.1021/ja037646m
Publikováno v:
Natural Product Reports; Nov2005, Vol. 22 Issue 6, p742-760, 19p