Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Byron Gajewski"'
Publikováno v:
BMC Medical Research Methodology, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Pediatric population presents several barriers for clinical trial design and analysis, including ethical constraints on the sample size and slow accrual rate. Bayesian adaptive design methods could be considered to address these c
Externí odkaz:
https://doaj.org/article/9b5cb534763c4702b821b8eb16e06007
Autor:
Dinesh Pal Mudaranthakam, Sam Pepper, Alexander Alsup, Tara Lin, Natalie Streeter, Jeffrey Thompson, Byron Gajewski, Matthew S. Mayo, Qamar Khan
Publikováno v:
Contemporary Clinical Trials Communications, Vol 30, Iss , Pp 101050- (2022)
Background: The study startup process for interventional clinical trials is a complex process that involves the efforts of many different teams. Each team is responsible for their startup checklist in which they verify that the necessary tasks are do
Externí odkaz:
https://doaj.org/article/434ae3c4bfef457a9e1364942bc02d40
Autor:
Jeffrey A. Thompson, Lynn Chollet-Hinton, John Keighley, Audrey Chang, Dinesh Pal Mudaranthakam, David Streeter, Jinxiang Hu, Michele Park, Byron Gajewski
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Rural residence is commonly thought to be a risk factor for poor cancer outcomes. However, a number of studies have reported seemingly conflicting information regarding cancer outcome disparities with respect to rural residence, w
Externí odkaz:
https://doaj.org/article/45a3b9e32bc84599b9cd638b162e7dfd
Autor:
Dinesh Pal Mudaranthakam, Byron Gajewski, Hope Krebill, James Coulter, Michelle Springer, Elizabeth Calhoun, Dorothy Hughes, Matthew Mayo, Gary Doolittle
Publikováno v:
JMIR Cancer, Vol 8, Iss 2, p e33240 (2022)
BackgroundThe National Clinical Trials Network program conducts phase 2 or phase 3 treatment trials across all National Cancer Institute’s designated cancer centers. Participant accrual across these clinical trials is a critical factor in deciding
Externí odkaz:
https://doaj.org/article/556a3a77a3414eb78a0f1e896b9af77c
Autor:
Dinesh Pal Mudaranthakam, Alexander M Alsup, Vinay Murakonda, Tara Lin, Jeffrey Thompson, Byron Gajewski, Matthew S Mayo
Publikováno v:
Cancer Informatics, Vol 21 (2022)
Objective: Participant recruitment is a challenge for any clinical trial but is especially complex in cancer specifically due to the need to initiate treatment urgently. Most participants enrolled in oncology clinical trials are identified as potenti
Externí odkaz:
https://doaj.org/article/971c26abd4674d68a556c1c481888236
Autor:
Dinesh Pal Mudaranthakam, Alexandra Brown, Elizabeth Kerling, Susan E Carlson, Christina J Valentine, Byron Gajewski
Publikováno v:
JMIR Formative Research, Vol 5, Iss 12, p e30368 (2021)
BackgroundAs the cost of clinical trials continues to rise, novel approaches are required to ensure ethical allocation of resources. Multisite trials have been increasingly utilized in phase 1 trials for rare diseases and in phase 2 and 3 trials to m
Externí odkaz:
https://doaj.org/article/bbcfad3d1cc5448c9e16f00969ee9ef3
Autor:
Benjamin Kasenda, Junhao Liu, Yu Jiang, Byron Gajewski, Cen Wu, Erik von Elm, Stefan Schandelmaier, Giusi Moffa, Sven Trelle, Andreas Michael Schmitt, Amanda K. Herbrand, Viktoria Gloy, Benjamin Speich, Sally Hopewell, Lars G. Hemkens, Constantin Sluka, Kris McGill, Maureen Meade, Deborah Cook, Francois Lamontagne, Jean-Marc Tréluyer, Anna-Bettina Haidich, John P. A. Ioannidis, Shaun Treweek, Matthias Briel
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-7 (2020)
Abstract Background Poor recruitment of patients is the predominant reason for early termination of randomized clinical trials (RCTs). Systematic empirical investigations and validation studies of existing recruitment models, however, are lacking. We
Externí odkaz:
https://doaj.org/article/c79d263ef5fd4452bc2bda724a308791
Publikováno v:
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-17 (2020)
Abstract Background Monitoring and reporting of drug safety during a clinical trial is essential to its success. More recent attention to drug safety has encouraged statistical methods development for monitoring and detecting potential safety signals
Externí odkaz:
https://doaj.org/article/f60ac27b22924783a7c658d7cacb2d4f
Autor:
Holly R. Hull, Amy Herman, Heather Gibbs, Byron Gajewski, Kelli Krase, Susan E. Carlson, Debra K. Sullivan, Jeannine Goetz
Publikováno v:
BMC Pregnancy and Childbirth, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Interventions to prevent excessive gestational weight gain (GWG) have had limited success This pilot study examined the effectiveness of a single goal (SG) high dietary fiber intervention to prevent excessive GWG. Methods Twelve w
Externí odkaz:
https://doaj.org/article/ff302ef48f1f4db49a3cd4f937056eba
Autor:
Dinesh Pal Mudaranthakam, Michele Park, Jeffrey Thompson, Alexander M. Alsup, Ron Krebill, Lynn Chollet Hinton, Jinxiang Hu, Byron Gajewski, Andrew Godwin, Matthew S Mayo, Jo Wick, Lisa Harlan-Williams, Jianghua He, Tami Gurley-Calvez
Publikováno v:
Preventive Medicine Reports, Vol 23, Iss , Pp 101446- (2021)
Breast cancer screening guidelines serve as crucial evidence-based recommendations in deciding when to begin regular screenings. However, due to developments in breast cancer research and differences in research interpretation, screening guidelines c
Externí odkaz:
https://doaj.org/article/6ce292b1a48a431bbce48d8f4b02a31a