Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Byron C, Knowles"'
Autor:
Victoria G. Weis, Byron C. Knowles, Eunyoung Choi, Anna E. Goldstein, Janice A. Williams, Elizabeth H. Manning, Joseph T. Roland, Lynne A. Lapierre, James R. Goldenring
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 2, Pp 131-157 (2016)
Background & Aims: Inactivating mutations in myosin Vb (MYO5B) cause severe neonatal diarrhea in microvillus inclusion disease. Loss of active MYO5B causes the formation of pathognomonic inclusions and aberrations in brush-border enzymes. Methods: We
Externí odkaz:
https://doaj.org/article/881b6fbdb2b844b88227fa71b975f80a
Autor:
Cameron Chesnut, Roberto Spreafico, Giovanni A. Botten, Byron C. Knowles, Mohammad Karimzada, Teresa Soriano, Brandon J. Thomas, Serghei Mangul, Philip O. Scumpia, Nima M. Gharavi, Jeremy Rotman, Amy R. Vandiver, Kevin Wesel
Publikováno v:
Exp Dermatol
Background Human papillomavirus (HPV) infection is known to promote the development of mucosal squamous cell carcinoma (mSCC), including pathologically high-grade lesions, but its role in cutaneous squamous cell carcinoma (cuSCC) remains unclear, par
Autor:
Lynne A. Lapierre, Victoria G. Weis, Mitchell D. Shub, Paul S. Dickman, Byron C. Knowles, James R. Goldenring, Martin G. Martin, Cameron Schlegel
Publikováno v:
Digestive Diseases and Sciences. 63:356-365
Microvillus inclusion disease (MVID) is a severe form of neonatal diarrhea, caused mainly by mutations in MYO5B. Inactivating mutations in MYO5B causes depolarization of enterocytes in the small intestine, which gives rise to chronic, unremitting sec
Autor:
Natalia, Vecerek, Elizabeth O, Dupuy, Yuna, Kang, G Peter, Sarantopoulos, Scott, Worswick, Byron C, Knowles
Publikováno v:
Dermatology online journal. 25(7)
We describe adult-onset Kawasaki disease (KD) and review clinical manifestations and treatment guidelines. Our patient is a 20-year-old female who initially presented to an outside hospital for fever, cervical lymphadenopathy, malaise, exudative tons
Autor:
Buhyun Lee, Ki Taek Nam, Joseph T. Roland, Byron C. Knowles, Haengdueng Jeong, Kwang H. Kim, Kyung Min Lim, Yejin Cho, Jeffrey P. Zwerner, James R. Goldenring
Publikováno v:
J Pathol
Rab25 can function as both a tumor suppressor and a tumor promoter across different tissues. This study sought to clarify the role of Rab25 as a tumor suppressor in skin squamous cell carcinoma (SCC). Rab25 loss was closely associated with neoplastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ea99fbf19c240757699734f6068518
https://europepmc.org/articles/PMC8075409/
https://europepmc.org/articles/PMC8075409/
Publikováno v:
BASE-Bielefeld Academic Search Engine
Langerhans cell histiocytosis (LCH) is a rare, clinically heterogeneous disease that most commonly occurs in pediatric populations. Congenital self-limited LCH is a benign variant of LCH. It most commonly presents as a diffuse eruption and reports of
Autor:
Matthew J. Tyska, Byron C. Knowles, Moorthy Krishnan, Mitchell D. Shub, Paul S. Dickman, James R. Goldenring, Joseph T. Roland, Lynne A. Lapierre
Publikováno v:
Journal of Clinical Investigation. 124:2947-2962
Microvillus inclusion disease (MVID) is a severe form of congenital diarrhea that arises from inactivating mutations in the gene encoding myosin Vb (MYO5B). We have examined the association of mutations in MYO5B and disruption of microvillar assembly
Publikováno v:
Molecular Biology of the Cell
Rab25 is a tumor suppressor in the colon, but the mechanisms underlying the influence of Rab25 on polarity are unknown. Findings on changes in polarity in Caco2-BBE cells with knockdown and rescue of Rab25 expression indicate that Rab25 regulates int
Autor:
Joseph T. Roland, Eun-Young Choi, Anna E. Goldstein, Victoria G. Weis, James R. Goldenring, Janice A. Williams, Lynne A. Lapierre, Elizabeth H. Manning, Byron C. Knowles
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
BASE-Bielefeld Academic Search Engine
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 2, Pp 131-157 (2016)
BASE-Bielefeld Academic Search Engine
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 2, Pp 131-157 (2016)
Background & Aims: Inactivating mutations in myosin Vb (MYO5B) cause severe neonatal diarrhea in microvillus inclusion disease. Loss of active MYO5B causes the formation of pathognomonic inclusions and aberrations in brush-border enzymes. Methods: We
Autor:
Nicole A. Ducharme, Joseph T. Roland, Lynne A. Lapierre, James R. Goldenring, Byron C. Knowles, Gerard Apodaca, Cathy M. Caldwell, Kenya M. Avant, Asli Oztan
Publikováno v:
Molecular Biology of the Cell
Ser-227 phosphorylation of Rab11-FIP2 by Par1b/MARK2 regulates the establishment of polarized epithelial monolayers in three-dimensional MDCK cell cultures and has an ongoing influence on the composition of both adherens and tight junctions in polari