Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Byron A. Wingerd"'
Autor:
Wenjun Bao, Geoffrey Mann, Thomas J Pedersen, Rebecca Lyzinski, Anisa Scott, Andrew J Foglia, John Cromer, Meichen Dong, Nora Varga, Sam Gardner, Christopher J Kirchberg, Byron A Wingerd, Russell D Wolfinger
Publikováno v:
Journal of the Society for Clinical Data Management. 3
The use of standardized data formats has increasingly facilitated both the submission of clinical trial data by pharmaceutical companies and its review by regulatory agencies. The Clinical Data Integration Standards Consortium (CDISC) format has beco
Publikováno v:
Journal of Biological Chemistry. 282:7961-7972
We have previously demonstrated that fibronectin (Fn) stimulates the proliferation of non-small cell lung carcinoma (NSCLC) cell growth through the induction of cyclooxygenase-2 (COX-2) and prostaglandin E2 secretion. Here, we demonstrate that NSCLC
Publikováno v:
The Journal of Immunology. 177:8111-8122
Infections involving LPS-bearing, Gram-negative bacteria can lead to acute inflammation and septic shock. Cyclooxygenase-2 (COX-2), the target of nonsteroidal anti-inflammatory drugs and selective COX-2 inhibitors, is importantly involved in these re
Publikováno v:
Journal of Biological Chemistry. 280:33240-33249
The prostaglandin E2 receptor subtype EP4 has been implicated in the growth and progression of human non-small cell lung carcinoma (NSCLC). However, the factors that control its expression have not been entirely elucidated. Our studies show that NSCL
Autor:
William L. Smith, Elizabeth D. Thuresson, Caroline Jill Rieke, R. Michael Garavito, Byron A. Wingerd, Michael G. Malkowski, Ying Sun, Renée Micielli, Anne M. Mulichak, Karen M. Lakkides
Publikováno v:
Journal of Biological Chemistry. 276:10347-10357
Prostaglandin endoperoxide H synthases (PGHSs) catalyze the committed step in the biosynthesis of prostaglandins and thromboxane, the conversion of arachidonic acid, two molecules of O2, and two electrons to prostaglandin endoperoxide H2 (PGH2). Form
Autor:
William L. Smith, Karen M. Lakkides, Byron A. Wingerd, Catherine Anne Miller, Toshiya Arakawa, David L. DeWitt, O. Laneuville
Publikováno v:
Journal of Biological Chemistry. 271:29569-29575
Prostaglandin endoperoxide H synthase-1 (PGHS-1) is expressed constitutively in murine NIH 3T3 cells and RAW 264.7 cells. PGHS-2 is inducibly expressed in these cells following stimulation with serum or bacterial lipopolysaccharide (LPS), respectivel
Prostaglandin endoperoxide H synthases (PGHSs) 1 and 2 convert arachidonic acid to prostaglandin H 2 in the committed step of prostanoid biosynthesis. These enzymes are pharmacological targets of nonsteroidal antiinflammatory drugs and cyclooxygenase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022b2fad0a17be93ba04276badea2d57
https://europepmc.org/articles/PMC1458845/
https://europepmc.org/articles/PMC1458845/
Autor:
Gregg A. Howe, Bonnie C. McCaig, Youfu Zhao, Lei Li, Eran Pichersky, Jihong Wang, Byron A. Wingerd, Mark E. Whalon
Publikováno v:
The Plant cell. 16(1)
Jasmonic acid (JA) is a fatty acid–derived signaling molecule that regulates a broad range of plant defense responses against herbivores and some microbial pathogens. Molecular genetic studies in Arabidopsis have established that JA also performs a
Autor:
Mark E. Whalon, Byron A. Wingerd
Publikováno v:
Archives of insect biochemistry and physiology. 54(4)
The insecticidal toxins from Bacillus thuringiensis (Bt) represent a class of biopesticides that are attractive alternatives to broad-spectrum "hard" chemistries. The U.S. Food Quality Protection Act and the European Economic Council directives aimed
Publikováno v:
Experimental cell research. 301(2)
Except functioning as lipid-lowering agents, HMG-CoA inhibitors, statins, are good tools to clarify the signaling role of small G proteins. In this study, we found in murine RAW264.7 macrophages, statins within 1-30 microM stimulated COX-2 gene trans