Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Byron, Kuo"'
Autor:
Robert Stainforth, Ngoc Vuong, Nadine Adam, Byron Kuo, Ruth C. Wilkins, Carole Yauk, Afshin Beheshti, Vinita Chauhan
Publikováno v:
International Journal of Radiation Biology. 98:1832-1844
Benchmark dose (BMD) modeling is a method commonly used in chemical toxicology to identify the point of departure (POD) from a dose-response curve linked to a health-related outcome. Recently, its application in the analysis of transcriptional data f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92583fe7bb692fa088b2d701c142a7b5
https://doi.org/10.1080/09553002.2022.2110300
https://doi.org/10.1080/09553002.2022.2110300
Autor:
Byron Kuo, Marc A. Beal, John W. Wills, Paul A. White, Francesco Marchetti, Andy Nong, Tara S. Barton-Maclaren, Keith Houck, Carole L. Yauk
Publikováno v:
Archives of Toxicology. 96:2067-2085
Funder: Canada Research Chairs; doi: http://dx.doi.org/10.13039/501100001804
Risk assessments are increasingly reliant on information from in vitro assays. The in vitro micronucleus test (MNvit) is a genotoxicity test that detects chromosomal ab
Risk assessments are increasingly reliant on information from in vitro assays. The in vitro micronucleus test (MNvit) is a genotoxicity test that detects chromosomal ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6a452403e942c033b914391c3e0fdc
https://doi.org/10.1007/s00204-022-03286-2
https://doi.org/10.1007/s00204-022-03286-2
Autor:
Ivy Moffat, Richard Carrier, Rémi Gagné, Andrea Rowan-Carroll, Julie Bourdon-Lacombe, Carole L. Yauk, Andrew Williams, Stephen S. Ferguson, A. Reardon, Karen Leingartner, Ella Atlas, Byron Kuo, Luigi Lorusso
Publikováno v:
Toxicological Sciences. 184:154-169
Per- and polyfluoroalkyl substances (PFAS) are some of the most prominent organic contaminants in human blood. Although the toxicological implications of human exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are well establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015587a0ab4a09f4a1ee9183bd192fa2
https://doi.org/10.1093/toxsci/kfab102
https://doi.org/10.1093/toxsci/kfab102
Autor:
Richard Carrier, Byron Kuo, Andrew Williams, Karen Leingartner, Julie Bourdon-Lacombe, Ella Atlas, Andrea Rowan-Carroll, Andy Nong, Rémi Gagné, Ivy Moffat, Carole L. Yauk, Stephen S. Ferguson, Luigi Lorusso, Matthew J. Meier, A. Reardon
Publikováno v:
Toxicological Sciences. 181:199-214
Per- and poly-fluoroalkyl substances (PFAS) are widely found in the environment because of their extensive use and persistence. Although several PFAS are well studied, most lack toxicity data to inform human health hazard and risk assessment. This st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a5f7ff9f9c8bd9c54fc263378efa0b
https://doi.org/10.1093/toxsci/kfab039
https://doi.org/10.1093/toxsci/kfab039
Autor:
Byron, Kuo, Marc A, Beal, John W, Wills, Paul A, White, Francesco, Marchetti, Andy, Nong, Tara S, Barton-Maclaren, Keith, Houck, Carole L, Yauk
Publikováno v:
Archives of toxicology. 96(7)
Risk assessments are increasingly reliant on information from in vitro assays. The in vitro micronucleus test (MNvit) is a genotoxicity test that detects chromosomal abnormalities, including chromosome breakage (clastogenicity) and/or whole chromosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dda6f097926ea86511c21ba0029e64a
https://pubmed.ncbi.nlm.nih.gov/35445829
https://pubmed.ncbi.nlm.nih.gov/35445829
Autor:
A Francina Webster, Nikolai Chepelev, Rémi Gagné, Byron Kuo, Leslie Recio, Andrew Williams, Carole L Yauk
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136764 (2015)
Many regulatory agencies are exploring ways to integrate toxicogenomic data into their chemical risk assessments. The major challenge lies in determining how to distill the complex data produced by high-content, multi-dose gene expression studies int
Externí odkaz:
https://doaj.org/article/6db69aed5a56455891a43c0b2f270c08
Autor:
Byron Kuo, L. Lorusso, I. Moffat, R. Carrier, Andrea Rowan-Carroll, Rémi Gagné, Andrew Williams, Carole L. Yauk, J. Bourdon-Lacombe, Ella Atlas, Stephen S. Ferguson, Karen Leingartner, A. Reardon
Per- and polyfluoroalkyl substances (PFAS) are some of the most prominent organic contaminants in human blood. Although the toxicological implications from human exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are well esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19dad6e6c9a73f272cb15b5b2160e968
https://doi.org/10.1101/2020.10.20.347328
https://doi.org/10.1101/2020.10.20.347328
Autor:
Ella Atlas, Nikolai L. Chepelev, Leslie Recio, Rémi Gagné, Cheryl A. Hobbs, Andrew Williams, Timothy Maynor, Kim G. Shepard, Carole L. Yauk, Vian Peshdary, Byron Kuo
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 72
Bisphenol A (BPA) is a chemical used in the manufacturing of plastics to which human exposure is ubiquitous. Numerous studies have linked BPA exposure to many adverse health outcomes prompting the replacement of BPA with various analogues including b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d82c4402e47fe6b57999cd14268bdc6
https://pubmed.ncbi.nlm.nih.gov/33476716
https://pubmed.ncbi.nlm.nih.gov/33476716
Autor:
A. Reardon, I. Moffat, Andy Nong, Rémi Gagné, Andrew Williams, R. Carrier, J. Bourdon-Lacombe, Matthew J. Meier, Ella Atlas, Stephen S. Ferguson, Andrea Rowan-Carroll, Carole L. Yauk, L. Lorusso, Karen Leingartner, Byron Kuo
Per- and poly-fluoroalkyl substances (PFAS) are widely found in the environment because of their extensive use and persistence. Although several PFAS are well studied, most lack toxicity data to inform human health hazard and risk assessment. This st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86568dbddd25edf862c017cfc3af1a9d
https://doi.org/10.1101/2020.10.15.341362
https://doi.org/10.1101/2020.10.15.341362
Autor:
Cheryl A. Hobbs, Timothy Maynor, Nikolai L. Chepelev, Byron Kuo, Leslie Recio, Carole L. Yauk, Rémi Gagné
Publikováno v:
Regulatory Toxicology and Pharmacology. 95:75-90
Acrylamide (AA) exposure causes increased incidence of forestomach, lung, and Harderian gland tumors in male mice. One hypothesized mode of action (MOA) for AA-carcinogenicity includes genotoxicity/mutagenicity as a key event, possibly resulting from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203933d2d87b3ddfa6c624be0cd08e1e
https://doi.org/10.1016/j.yrtph.2018.02.005
https://doi.org/10.1016/j.yrtph.2018.02.005