Transient Inhibition of Translation Improves Cardiac Function After Ischemia/Reperfusion by Attenuating the Inflammatory Response.

Autor: Hofmann C; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.).; Faculty of Biosciences, Heidelberg University, Germany (C.H.)., Serafin A; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Schwerdt OM; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Fischer J; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany., Sicklinger F; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Younesi FS; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Byrne NJ; University Heart Center Graz, Department of Cardiology, Medical University of Graz, Austria (N.J.B., H.B.)., Meyer IS; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Malovrh E; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Sandmann C; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Jürgensen L; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Kamuf-Schenk V; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Stroh C; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Löwenthal Z; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Finke D; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Boileau E; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Beisaw A; Department of Internal Medicine VIII (A.B.), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Bugger H; University Heart Center Graz, Department of Cardiology, Medical University of Graz, Austria (N.J.B., H.B.)., Rettel M; Proteomics Core Facility, European Molecular Biology Laboratory Heidelberg, Germany (M.R., F. Stein)., Stein F; Proteomics Core Facility, European Molecular Biology Laboratory Heidelberg, Germany (M.R., F. Stein)., Katus HA; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Jakobi T; Department of Internal Medicine and the Translational Cardiovascular Research Center, University of Arizona, College of Medicine-Phoenix (T.J.)., Frey N; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Leuschner F; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.)., Völkers M; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology [C.H., A.S., O.M.S., J.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., H.A.K., N.F., F.L., M.V.]), Heidelberg University Hospital, Germany.; German Center for Cardiovascular Research, Partner Site Heidelberg/Mannheim, Heidelberg (C.H., A.S., O.M.S., A.F., F. Sicklinger, F.S.Y., I.S.M., E.M., C. Sandmann, L.J., V.K.-S., C. Stroh, Z.L., D.F., E.B., A.B., H.A.K., N.F., F.L., M.V.).

Publikováno v: Circulation [Circulation] 2024 Oct 15; Vol. 150 (16), pp. 1248-1267. Date of Electronic Publication: 2024 Aug 29.

A streamlined, automated workflow to screen and triage large numbers of baculoviruses for protein expression.

Autor: Kostas JJ; Protein & Structural Chemistry, Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Partridge AT; Protein & Structural Chemistry, Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Byrne NJ; Protein & Structural Chemistry, Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Edwards RW; Evotec (US) Inc., 303B College Road East, Princeton, NJ 08540, USA., Su HP; Protein & Structural Chemistry, Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Gabelli SB; Protein & Structural Chemistry, Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Brooun A; Protein & Structural Chemistry, Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Shipman JM; Protein & Structural Chemistry, Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA. Electronic address: jennifer_shipman@merck.com.

Publikováno v: Protein expression and purification [Protein Expr Purif] 2024 Mar; Vol. 215, pp. 106406. Date of Electronic Publication: 2023 Nov 21.

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Animal Models of Dysregulated Cardiac Metabolism.

Autor: Bugger H; University Heart Center Graz, Department of Cardiology, Medical University of Graz, Graz, Austria, Austria (H.B., N.J.B.)., Byrne NJ; University Heart Center Graz, Department of Cardiology, Medical University of Graz, Graz, Austria, Austria (H.B., N.J.B.)., Abel ED; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles (E.D.A.).

Publikováno v: Circulation research [Circ Res] 2022 Jun 10; Vol. 130 (12), pp. 1965-1993. Date of Electronic Publication: 2022 Jun 09.

Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments

Autor: Tijanic N, Solomon Shorser, Rosenberg Mw, Mijalkovic S, Byrne Nj, André Kahles, Rolf Kabbe, Larsson Omberg, Jules Kerssemakers, Olivier Harismendy, Romina Royo, Michael Heinold, Francis Ouellette B, Jonas Demeulemeester, Zhao Chen, Satoru Miyano, Peter J. Campbell, Short C, Ocana D, Oliver Hofmann, Raine Km, April E. Williams, Hong Jh, Mihaiescu Gl, Adam Butler, Denis Yuen, Jongsun Jung, Sergei Yakneen, Kovacevic M, Carolyn M. Hutter, Miyoshi N, Vicente D, Hidewaki Nakagawa, Steven Newhouse, Manuel Prinz, Andy Cafferkey, Johannes Werner, Yong Ho Kim, Nicholson J, Esther Rheinbay, Matthias Schlesner, David Torrents, Ivkovic S, Sung-Hoon Cho, Joachim Weischenfeldt, Lazic Am, Jeon S, Thomas J. Hudson, Julian M. Hess, Fayzullaev N, Nahal Hk, Gad Getz, Peter Van Loo, Dimitri Livitz, Perry, Ivo Buchhalter, Rodriguez Jb, Nagarajan Paramasivam, Michelle Dow, Young-Choon Woo, Ignaty Leshchiner, Paul Flicek, Robert L. Grossman, Jonathan Spring, Jeremiah Wala, Roland Eils, Grace Tiao, Kyle Ellrott, Angela N. Brooks, Heidi J. Sofia, Josep Lluís Gelpí, Barbara Hutter, Francesco Favero, Brian O'Connor, Lucila Ohno-Machado, Peter Clapham, Nastic M, Choi W, De La Vega Fm, L. J. Dursi, Montserrat Puiggròs, Ohi K, Wei Jiao, Brandi N. Davis-Dusenbery, Qian Xiang, Adam J Struck, Gibson B, Ferretti, Claudiu Farcas, Koscher M, Koures A, Lincoln Stein, Keith A. Boroevich, Jan O. Korbel, Gordon Saksena, Radovic P, Christian Lawerenz, Alex Buchanan, Christina K. Yung, Adam Wright, Nuno A. Fonseca, Todd Pihl, Jae H. Kim, Zhining Wang, Boyce R, Miguel Vazquez, Jürgen Eils, Kim H, Junjun Zhang, Seiya Imoto, Kortine Kleinheinz, Daniel Huebschmann

The International Cancer Genome Consortium (ICGC)’s Pan-Cancer Analysis of Whole Genomes (PCAWG) project aimed to categorize somatic and germline variations in both coding and non-coding regions in over 2,800 cancer patients. To provide this datase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90d76ea28cb1ca5039f28a82651baec