CORRELATIONOFB-LINESON LUNGULTRASOUND AND NT PRO BNP TODIFFERENTIATE BETWEEN ACUTE HEARTFAILURE FROM OTHER NON CARDIOGENICCAUSESOFDYSPNEA-APROSPECTIVEDIAGNOSTICSTUDY

Autor: Varun Byrappa, V, Vinayak Panchgar, Shivaraddi Bhandi, Anagha, S.

Background:Dyspnea can be a manifestation of a variety of clinical conditions like acuteheart failure (AHF), chronic obstructive pulmonary disease (COPD), pneumonia, pulmonaryembolism and asthma. Dyspnea can prove to be life threatening and therefore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a1e047eedfccb5e27326f136bf2bbf

Immunogenetic losses co-occurred with seahorse male pregnancy and mutation in tlx1 accompanied functional asplenia

Autor: Yali Liu, Meng Qu, Han Jiang, Ralf Schneider, Geng Qin, Wei Luo, Haiyan Yu, Bo Zhang, Xin Wang, Yanhong Zhang, Huixian Zhang, Zhixin Zhang, Yongli Wu, Yingyi Zhang, Jianping Yin, Si Zhang, Byrappa Venkatesh, Olivia Roth, Axel Meyer, Qiang Lin

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Seahorses may have required adaptations to avoid immunological rejection of allogenic embryos by males. The authors show that a single substitution in tlx1 is associated with loss of the spleen in seahorses, and that across the clade, degree of male

Externí odkaz: https://doaj.org/article/d8a3cfe3301746b8a83eb0cd8873383b

The different fates of two Asian horseshoe crab species with different dispersal abilities

Autor: Qian Tang, Prashant Shingate, Yusli Wardiatno, Akbar John, Boon Hui Tay, Ywee Chieh Tay, Laura‐Marie Yap, Jasmin Lim, Hor Yee Tong, Karenne Tun, Byrappa Venkatesh, Frank E. Rheindt

Publikováno v: Evolutionary Applications, Vol 14, Iss 8, Pp 2124-2133 (2021)

Abstract Impending anthropogenic climate change will severely impact coastal organisms at unprecedented speed. Knowledge on organisms’ evolutionary responses to past sea‐level fluctuations and estimation of their evolutionary potential is therefo

Externí odkaz: https://doaj.org/article/dfaba4135d6b4a81a5da1272c7837a2a

Genome sequences reveal global dispersal routes and suggest convergent genetic adaptations in seahorse evolution

Autor: Chunyan Li, Melisa Olave, Yali Hou, Geng Qin, Ralf F. Schneider, Zexia Gao, Xiaolong Tu, Xin Wang, Furong Qi, Alexander Nater, Andreas F. Kautt, Shiming Wan, Yanhong Zhang, Yali Liu, Huixian Zhang, Bo Zhang, Hao Zhang, Meng Qu, Shuaishuai Liu, Zeyu Chen, Jia Zhong, He Zhang, Lingfeng Meng, Kai Wang, Jianping Yin, Liangmin Huang, Byrappa Venkatesh, Axel Meyer, Xuemei Lu, Qiang Lin

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

A new seahorse genome and the re-sequenced genomes of 21 other species shed new light on the evolutionary origin and global dispersal routes of seahorses, and show that bony spines—a key adaptation against predation—probably evolved multiple time

Externí odkaz: https://doaj.org/article/4c6a58d53f7140b1ae6ebc48c1b1ee50

Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy

Autor: Holger Hengel, Célia Bosso-Lefèvre, George Grady, Emmanuelle Szenker-Ravi, Hankun Li, Sarah Pierce, Élise Lebigot, Thong-Teck Tan, Michelle Y. Eio, Gunaseelan Narayanan, Kagistia Hana Utami, Monica Yau, Nader Handal, Werner Deigendesch, Reinhard Keimer, Hiyam M. Marzouqa, Meral Gunay-Aygun, Michael J. Muriello, Helene Verhelst, Sarah Weckhuysen, Sonal Mahida, Sakkubai Naidu, Terrence G. Thomas, Jiin Ying Lim, Ee Shien Tan, Damien Haye, Michèl A. A. P. Willemsen, Renske Oegema, Wendy G. Mitchell, Tyler Mark Pierson, Marisa V. Andrews, Marcia C. Willing, Lance H. Rodan, Tahsin Stefan Barakat, Marjon van Slegtenhorst, Ralitza H. Gavrilova, Diego Martinelli, Tal Gilboa, Abdullah M. Tamim, Mais O. Hashem, Moeenaldeen D. AlSayed, Maha M. Abdulrahim, Mohammed Al-Owain, Ali Awaji, Adel A. H. Mahmoud, Eissa A. Faqeih, Ali Al Asmari, Sulwan M. Algain, Lamyaa A. Jad, Hesham M. Aldhalaan, Ingo Helbig, David A. Koolen, Angelika Riess, Ingeborg Kraegeloh-Mann, Peter Bauer, Suleyman Gulsuner, Hannah Stamberger, Alvin Yu Jin Ng, Sha Tang, Sumanty Tohari, Boris Keren, Laura E. Schultz-Rogers, Eric W. Klee, Sabina Barresi, Marco Tartaglia, Hagar Mor-Shaked, Sateesh Maddirevula, Amber Begtrup, Aida Telegrafi, Rolph Pfundt, Rebecca Schüle, Brian Ciruna, Carine Bonnard, Mahmoud A. Pouladi, James C. Stewart, Adam Claridge-Chang, Dirk J. Lefeber, Fowzan S. Alkuraya, Ajay S. Mathuru, Byrappa Venkatesh, Joseph J. Barycki, Melanie A. Simpson, Saumya S. Jamuar, Ludger Schöls, Bruno Reversade

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

UDP-glucuronic acid is a component of the extracellular matrix. Here, the authors report biallelic variants in the gene encoding UDP-Glucose 6-Dehydrogenase (UGDH) in individuals affected by developmental epileptic encephalopathies that impair UGDH s

Externí odkaz: https://doaj.org/article/669f0574667343e2aba272d086c020c6