Acacetin Inhibits the Growth of STAT3-Activated DU145 Prostate Cancer Cells by Directly Binding to Signal Transducer and Activator of Transcription 3 (STAT3)

Autor: Sun Yun, Yu-Jin Lee, Jiyeon Choi, Nam Doo Kim, Dong Cho Han, Byoung-Mog Kwon

Publikováno v: Molecules, Vol 26, Iss 20, p 6204 (2021)

Signal transducer and activator of transcription 3 (STAT3) plays a critical role in the formation and growth of human cancer. Therefore, STAT3 is a therapeutic target for cancer drug discovery. Acacetin, a flavone present in various plants, inhibits

Externí odkaz: https://doaj.org/article/c780334438b34125b2e7693f392677af

Supplementary Figures 1-3 from Cryptotanshinone Inhibits Constitutive Signal Transducer and Activator of Transcription 3 Function through Blocking the Dimerization in DU145 Prostate Cancer Cells

Autor: Byoung-Mog Kwon, Dong Cho Han, Seung-Jun Kim, Young Ju Yoon, Ki Deok Shin, Hye-Nan Kim, Dae-Seop Shin

Supplementary Figures 1-3 from Cryptotanshinone Inhibits Constitutive Signal Transducer and Activator of Transcription 3 Function through Blocking the Dimerization in DU145 Prostate Cancer Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0cfc9de5b1a35d687507c569bbde5d
https://doi.org/10.1158/0008-5472.22376963

Acacetin Inhibits the Growth of STAT3-Activated DU145 Prostate Cancer Cells by Directly Binding to Signal Transducer and Activator of Transcription 3 (STAT3)

Autor: Nam Doo Kim, Sun Yun, Jiyeon Choi, Byoung-Mog Kwon, Dong Cho Han, Yu-Jin Lee

Publikováno v: Molecules
Volume 26
Issue 20
Molecules, Vol 26, Iss 6204, p 6204 (2021)

Signal transducer and activator of transcription 3 (STAT3) plays a critical role in the formation and growth of human cancer. Therefore, STAT3 is a therapeutic target for cancer drug discovery. Acacetin, a flavone present in various plants, inhibits

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e932251ada6b29729ca7594f73f5fa7

Benproperine, an ARPC2 inhibitor, suppresses cancer cell migration and tumor metastasis

Autor: Seung-Wook Chi, Su-Kyung Lee, Jeong Hee Moon, Chang Woo Lee, Jieun Yun, Yae Jin Yoon, Jiyeon Choi, Yu-Jin Lee, Jong Soon Kang, Sangku Lee, Dong Cho Han, Young-Min Han, Byoung-Mog Kwon

Publikováno v: Biochemical Pharmacology. 163:46-59

Metastasis is the leading cause of cancer mortality and cancer cell migration is an essential stage of metastasis. We identified benproperine (Benp, a clinically used antitussive drug) as an inhibitor of cancer cell migration and an anti-metastatic a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85329ac30c51117579a4322cca431ed
https://doi.org/10.1016/j.bcp.2019.01.017

Contributors

Autor: Behnaz Abiri, Sadia Afrin, Yolanda Aguilera, Mazhar Al Zoubi, Alaa Aljabali, Anmar Al-Taie, Tsukuru Amano, Pilar Amiano, Ayca Ant, Mahboobeh Ashrafi, Charles Elias Assmann, Arzu Atalay, Luigi Avallone, Khaled Aziz, Margarete Dulce Bagatini, Giuseppina Barrera, Saime Batırel, Maurizio Battino, Onur Bender, Daniel Pereira Bezerra, Ranjana Bhandari, Marco Bisoffi, Bianka Bojková, Chanchai Boonla, Garry R. Buettner, David Bynum, Viola Calabrò, Gloria M. Calaf, Domenico Carotenuto, Rory S. Carroll, Tokuhiro Chano, Matthew Cheesman, Rong-Jane Chen, Francesca Ciani, Natascia Cocchia, Ian Edwin Cock, João G. Costa, Marie Angele Cucci, Joseph J. Cullen, Jéssica Righi da Rosa, Beatriz da Silva Rosa Bonadiman, Sreemanti Das, Christophe Deben, Andrea Devecchi, Valentina D'Onofrio, Sepideh Elyasi, Fatma Ceyla Eraldemir, Luigi Esposito, Maurizio Fadda, Bianca Cristine Favero-Santos, Ana S. Fernandes, Cíntia Ferreira-Pêgo, Concetta Finocchiaro, Cesira Foppoli, Tamara Y. Forbes-Hernández, Laurie Freire Boullosa, Jessica Gambardella, Belén García-Villanova, Alexandros G. Georgakilas, Francesca Giampieri, Yolanda Gilaberte, Maria Cristina Cintra Gomes-Marcondes, Salvador Gonzalez, Elvira Gonzalez de Mejia, Luis Goya, Margherita Grattarola, Eduardo Jesús Guerra-Hernández, Marta Halasa, Zuhair Mohammad Hassan, Vasiliki I. Hatzi, Cristan A. Herbert, Guido Iaccarino, Mirko Ippolito, Fikret Vehbi Izzettin, Angeles Juarranz, Daehee Kang, Rui Kang, Garima Khanna, Anisur Rahman Khuda-Bukhsh, Tuğcan Korak, Anurag Kuhad, Natalia Kurhaluk, Byoung-Mog Kwon, Sang-Ah Lee, Jinthe Van Loenhout, Wei Sheng Joshua Loke, Pâmela Longhi, Olga A. Martin, Maria Angeles Martín, Maria A. Martín-Cabrejas, Lucianna Maruccio, Emmanuel Mfotie Njoya, Natalia Angelo da Silva Miyaguti, Mahdieh Molanouri Shamsi, Esther Molina-Montes, Amir Mousapasandi, Somaira Nowsheen, Justin M. O’Neill, Jane O’Sullivan, Karolina Okla, Melina de Moraes Santos Oliveira, Nuno G. Oliveira, Sarah Christine Pereira de Oliveira, Audrei de Oliveira Alves, Concepción Parrado, Vinood B. Patel, Marzia Perluigi, Rumana Pervin, Neena Philips, Costanza Pira, Stefania Pizzimenti, Md. Moyen Uddin Pk, Alessandra Pollice, Sahdeo Prasad, Victor R. Preedy, Matiar Rahman, Rajkumar Rajendram, Sonia Ramos, Miguel Rebollo-Hernanz, Richard Richardson, Santu Kumar Saha, Sweta Sharma Saha, Carla de Moraes Salgado, Mesut Sancar, Woo-Kyoung Shin, Masaki Shiota, Tahoora Shomali, Halyna Siomyk, Shankar Siva, Daniela Sorriento, Sanjay K. Srivastava, Hidekazu Suzuki, Simona Tafuri, Daolin Tang, Paul S. Thomas, Ioanna Tremi, Hitoshi Tsugawa, Malgorzata Tyszka-Czochara, Mohammadreza Vafa, Jessica Ventura, Laís Rosa Viana, Bojana B. Vidović, Ying-Jan Wang, Anna Wawruszak, Grazielle Castagna Cezimbra Weis, Pawel J. Winklewski, Yae Jin Yoon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ab8ccc6bbbb4751ecda365ec4221c8e
https://doi.org/10.1016/b978-0-12-819547-5.09988-0