Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Byoung-Mog Kwon"'
Autor:
Hyun-Jin Jang, Yae Jin Yoon, Jiyeon Choi, Yu-Jin Lee, Sangku Lee, Wansang Cho, Wan Gi Byun, Seung Bum Park, Dong Cho Han, Byoung-Mog Kwon
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1462 (2022)
Metastasis, in which cancer cells migrate to other tissues and form new tumors, is a major cause of both cancer death and treatment failure. In a previous study, benproperine (Benp) was identified as a cancer cell migration inhibitor and an inhibitor
Externí odkaz:
https://doaj.org/article/b9cec002f04240e2aa3504c94c6f7146
Publikováno v:
Molecules, Vol 26, Iss 20, p 6204 (2021)
Signal transducer and activator of transcription 3 (STAT3) plays a critical role in the formation and growth of human cancer. Therefore, STAT3 is a therapeutic target for cancer drug discovery. Acacetin, a flavone present in various plants, inhibits
Externí odkaz:
https://doaj.org/article/c780334438b34125b2e7693f392677af
Autor:
Sangah Lee, Jiyae Jung, Yu-Jin Lee, Seon-Kyu Kim, Jung-Ae Kim, Bo-Kyung Kim, Kyung Chan Park, Byoung-Mog Kwon, Dong Cho Han
Publikováno v:
Cancers, Vol 13, Iss 12, p 2987 (2021)
Although EGFR-TKI treatment of NSCLC (non-small-cell lung cancer) patients often achieves profound initial responses, the efficacy is transient due to acquired resistance. Multiple receptor tyrosine kinase (RTK) pathways contribute to the resistance
Externí odkaz:
https://doaj.org/article/53abc92a58854de4b5e7a7e101217829
Autor:
Byoung-Mog Kwon, Dong Cho Han, Seung-Jun Kim, Young Ju Yoon, Ki Deok Shin, Hye-Nan Kim, Dae-Seop Shin
Because signal transducer and activator of transcription 3 (STAT3) is constitutively activated in most human solid tumors and is involved in the proliferation, angiogenesis, immune evasion, and antiapoptosis of cancer cells, researchers have focused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa40db1b149dd0bfc2c186177490b17c
https://doi.org/10.1158/0008-5472.c.6498389.v1
https://doi.org/10.1158/0008-5472.c.6498389.v1
Autor:
Byoung-Mog Kwon, Dong Cho Han, Seung-Jun Kim, Young Ju Yoon, Ki Deok Shin, Hye-Nan Kim, Dae-Seop Shin
Supplementary Figures 1-3 from Cryptotanshinone Inhibits Constitutive Signal Transducer and Activator of Transcription 3 Function through Blocking the Dimerization in DU145 Prostate Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0cfc9de5b1a35d687507c569bbde5d
https://doi.org/10.1158/0008-5472.22376963
https://doi.org/10.1158/0008-5472.22376963
Autor:
Sung-Yun Cho, Hyo-Jeong Lee, Hyo-Jung Lee, Deok-Beom Jung, Hyunseok Kim, Eun Jung Sohn, Bonglee Kim, Ji Hoon Jung, Byoung-Mog Kwon, Sung-Hoon Kim
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)
Publikováno v:
Molecules
Volume 26
Issue 20
Molecules, Vol 26, Iss 6204, p 6204 (2021)
Volume 26
Issue 20
Molecules, Vol 26, Iss 6204, p 6204 (2021)
Signal transducer and activator of transcription 3 (STAT3) plays a critical role in the formation and growth of human cancer. Therefore, STAT3 is a therapeutic target for cancer drug discovery. Acacetin, a flavone present in various plants, inhibits
Autor:
Dong Cho Han, Yu-Jin Lee, Jiyae Jung, Kyung Chan Park, Byoung-Mog Kwon, Sangah Lee, Jung-Ae Kim, Bo Kyung Kim, Seon-Kyu Kim
Publikováno v:
Cancers, Vol 13, Iss 2987, p 2987 (2021)
Cancers
Volume 13
Issue 12
Cancers
Volume 13
Issue 12
Simple Summary We attempted to identify target proteins and compounds that can be used to overcome EGFR-TKI resistance in NSCLC. To accomplish this, we generated EGFR inhibitor erlotinib-resistant HCC827-ErlR cells and obtained a list of differential
Autor:
Seung-Wook Chi, Su-Kyung Lee, Jeong Hee Moon, Chang Woo Lee, Jieun Yun, Yae Jin Yoon, Jiyeon Choi, Yu-Jin Lee, Jong Soon Kang, Sangku Lee, Dong Cho Han, Young-Min Han, Byoung-Mog Kwon
Publikováno v:
Biochemical Pharmacology. 163:46-59
Metastasis is the leading cause of cancer mortality and cancer cell migration is an essential stage of metastasis. We identified benproperine (Benp, a clinically used antitussive drug) as an inhibitor of cancer cell migration and an anti-metastatic a
Autor:
Yu-Jin Lee, Young-Hwan Kim, Byoung-Mog Kwon, Dong Cho Han, Yae Jin Yoon, Jiyeon Choi, Cheol-Hee Kim
Publikováno v:
Cancer Science
Inhibition of the signal transducer and activator of transcription 3 (STAT3) signaling pathway is a novel therapeutic strategy to treat human cancers with constitutively active STAT3. During the screening of natural products to find STAT3 inhibitors,