Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Byoung-Dae Lee"'
Autor:
Eunhae Jeon, Myeong-Seong Seo, Enkhmaa Lkhagva-Yondon, Yu-Ree Lim, Seung-Woo Kim, Yu Jeong Kang, Jun Seok Lee, Byoung Dae Lee, Rayul Wi, So-Yoon Won, Young Cheul Chung, Eun S. Park, Eunhee Kim, Byung Kwan Jin, Myung-Shin Jeon
Publikováno v:
Cell Death and Disease, Vol 15, Iss 11, Pp 1-11 (2024)
Abstract Levodopa (L-DOPA) treatment is a clinically effective strategy for improving motor function in patients with ischemic stroke. However, the mechanisms by which modulating the dopamine system relieves the pathology of the ischemic brain remain
Externí odkaz:
https://doaj.org/article/90e367a27a9a466fb220a4601dc21a51
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
To date, many studies using the controlled cortical impact (CCI) mouse model of traumatic brain injury (TBI) have presented results without presenting the pathophysiology of the injury-core itself or the temporal features of hemorrhage (Hrr). This mi
Externí odkaz:
https://doaj.org/article/0217384498ec4fdb8be42a9043eb89ab
Publikováno v:
Animal Cells and Systems, Vol 22, Iss 2, Pp 140-147 (2018)
Parkinson’s disease (PD) is the second most common neurodegenerative disease. Although most PD cases are sporadic, 5–10% of them are hereditary and several pathogenic mutations in related genes have been identified. Mutations in TMEM230 were rece
Externí odkaz:
https://doaj.org/article/de85f2ad140644b78524c66df7f174b4
Autor:
Ga Ram Jeong, Eun-Hae Jang, Jae Ryul Bae, Soyoung Jun, Ho Chul Kang, Chi-Hu Park, Joo-Ho Shin, Yukio Yamamoto, Keiko Tanaka-Yamamoto, Valina L. Dawson, Ted M. Dawson, Eun-Mi Hur, Byoung Dae Lee
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-17 (2018)
Abstract Background Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial and sporadic Parkinson’s disease (PD). Elevated kinase activity is associated with LRRK2 toxicity, but the substrates that mediate neurodege
Externí odkaz:
https://doaj.org/article/82ef80fe0e5944a3bd82d33b19606f98
Autor:
Hwon Heo, Juyeong Jo, Jae In Jung, Young-Min Han, Seongsoo Lee, Song Rae Kim, Seung-Hae Kwon, Kil-Nam Kim, Byung Joon Hwang, Yun Kee, Byoung Dae Lee, Dongmin Kang, Song Her
Publikováno v:
Biology Open, Vol 8, Iss 1 (2019)
Bioluminescence imaging has proven to be a highly sensitive technique for assessing in vitro transcriptional activity toward understanding gene regulation patterns; however, application of this technique is limited for brain research. In particular,
Externí odkaz:
https://doaj.org/article/537bd6934ef14a99a529d05ad1aa3061
Autor:
Ga Ram Jeong, Byoung Dae Lee
Publikováno v:
Cells, Vol 9, Iss 12, p 2565 (2020)
Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) are common genetic risk factors for both familial and sporadic Parkinson’s disease (PD). Pathogenic mutations in LRRK2 have been shown to induce changes in its activity, and abnorm
Externí odkaz:
https://doaj.org/article/15a687ce5e414385b903e56d4c463a02
Autor:
Eun-Mi Hur, Byoung Dae Lee
Publikováno v:
International Neurourology Journal, Vol 18, Iss 4, Pp 171-178 (2014)
Microtubules have been among the most successful targets in anticancer therapy and a large number of microtubule-targeting agents (MTAs) are in various stages of clinical development for the treatment of several malignancies. Given that injury and di
Externí odkaz:
https://doaj.org/article/1c4b7ee7bcf84cef8f29d69f57453ddb
Publikováno v:
BMB Reports
Recent evidence from genetics, animal model systems and biochemical studies suggests that defects in membrane trafficking play an important part in the pathophysiology of Parkinson's disease (PD). Mutations in leucine-rich repeat kinase 2 (LRRK2) con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0babf2adb573e1cc03e5072ae640eb9f
https://doi.org/10.5483/bmbrep.2019.52.9.186
https://doi.org/10.5483/bmbrep.2019.52.9.186
Autor:
Young Pil Kim, Dongsun Park, Jae Jin Kim, Won-Jae Chi, Sun Hee Lee, Seo Yun Lee, Soyeon Kim, Jee Min Chung, Jinseon Jeon, Byoung Dae Lee, Joo-Ho Shin, Yun-Il Lee, Hyeseong Cho, Jeong-Min Lee, Ho Chul Kang
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113442 (2014)
Cetuximab, a chimeric monoclonal antibody developed for targeting the Epidermal Growth Factor Receptor (EGFR), has been intensively used to treat cancer patients with metastatic colorectal cancer and head and neck cancer. Intact immunoglobulin G (IgG
Externí odkaz:
https://doaj.org/article/135b565cd1244178afbe2f3952b03642
Publikováno v:
Frontiers in Neurology
Frontiers in Neurology, Vol 12 (2021)
Frontiers in Neurology, Vol 12 (2021)
To date, many studies using the controlled cortical impact (CCI) mouse model of traumatic brain injury (TBI) have presented results without presenting the pathophysiology of the injury-core itself or the temporal features of hemorrhage (Hrr). This mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28d4fc525e50dea0de49286fac0468e
https://pubmed.ncbi.nlm.nih.gov/34650505
https://pubmed.ncbi.nlm.nih.gov/34650505