Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Byong H, Kang"'
Autor:
Noor Momin, Joseph R. Palmeri, Emi A. Lutz, Noor Jailkhani, Howard Mak, Anthony Tabet, Magnolia M. Chinn, Byong H. Kang, Virginia Spanoudaki, Richard O. Hynes, K. Dane Wittrup
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Understanding the pharmacokinetics of locally-injected drugs could aid in the design of immunotherapies to maximize their therapeutic effect. Here, by evaluating different IL-2 fusion proteins, the authors show that molecular weight and matrix bindin
Externí odkaz:
https://doaj.org/article/29c0b5b17b1041eaaa47f6822400abb3
Autor:
Beth E. Grace, Coralie M. Backlund, Duncan M. Morgan, Byong H. Kang, Nishant K. Singh, Brooke D. Huisman, C. Garrett Rappazzo, Kelly D. Moynihan, Laura Maiorino, Connor S. Dobson, Taeyoon Kyung, Khloe S. Gordon, Patrick V. Holec, Overbeck C. Takou Mbah, Daniel Garafola, Shengwei Wu, J. Christopher Love, K. Dane Wittrup, Darrell J. Irvine, Michael E. Birnbaum
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
While immune checkpoint blockade results in durable responses for some patients, many others have not experienced such benefits. These treatments rely upon reinvigorating specific T cell-antigen interactions. However, it is often unknown what antigen
Externí odkaz:
https://doaj.org/article/974ae2fd3083480d86e6565189e0552e
Autor:
Byong H Kang, Noor Momin, Kelly D Moynihan, Murillo Silva, Yingzhong Li, Darrell J Irvine, K Dane Wittrup
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248903 (2021)
Following curative immunotherapy of B16F10 tumors, ~60% of mice develop a strong antibody response against cell-surface tumor antigens. Their antisera confer prophylactic protection against intravenous challenge with B16F10 cells, and also cross-reac
Externí odkaz:
https://doaj.org/article/71a03d82b9834e24a26869f51fafa8cd
Autor:
Emi A Lutz, Noor Jailkhani, Noor Momin, Ying Huang, Allison Sheen, Byong H Kang, K Dane Wittrup, Richard O Hynes
Publikováno v:
PNAS Nexus. 1
Confining cytokine exposure to the tumors would greatly enhance cancer immunotherapy safety and efficacy. Immunocytokines, cytokines fused to tumor-targeting antibodies, have been developed with this intention, but without significant clinical succes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3624496f8abe36a592153972047ebb4
https://doi.org/10.1093/pnasnexus/pgac244
https://doi.org/10.1093/pnasnexus/pgac244
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2491
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98a02291519bc7ff89c9e1c02beed4f9
https://pubmed.ncbi.nlm.nih.gov/35482183
https://pubmed.ncbi.nlm.nih.gov/35482183
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2491
Yeast surface display is a powerful directed evolution method for developing and engineering protein molecules to attain desired properties. Here, updated protocols are presented for purposes of identification of lead binders and their affinity matur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78415f16e83ee3584f88603e5e9dbf27
https://pubmed.ncbi.nlm.nih.gov/35713851
https://pubmed.ncbi.nlm.nih.gov/35713851
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622841
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afb2feb0870ceb4d61be44effd1cedaa
https://doi.org/10.1007/978-1-0716-2285-8_27
https://doi.org/10.1007/978-1-0716-2285-8_27
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622841
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce02f2a0942223dd3db83555f8b33ec
https://doi.org/10.1007/978-1-0716-2285-8_2
https://doi.org/10.1007/978-1-0716-2285-8_2
Autor:
Neena Kashyap, Stephen A. Migueles, April Poole, Alyssa A. Pullano, Jinghe Huang, Mark Connors, Marc Gurwith, Florian Krammer, C. Jason Liang, Daniel Stadlbauer, Sarah Stuccio, Kenta Matsuda, Jessica Pederson, Jeff Alexander, Byong H. Kang, Kelly M. Martins, Angelique Biancotto, Sean Evans, Lyuba Bolkhovitinov, Tulley Shofner, Elise Ishida, Nathaniel E Wright, Julián Candia, Trevor Griesman, Matthew G. Zimmerman, Andy Patamawenu, Jon Smith, Giovanna Fantoni
Publikováno v:
J Clin Invest
BACKGROUND: To understand the features of a replicating vaccine that might drive potent and durable immune responses to transgene-encoded antigens, we tested a replication-competent adenovirus type 4 encoding influenza virus H5 HA (Ad4-H5-Vtn) admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9fed41486a4acfa07dd26c87e64e84
https://pubmed.ncbi.nlm.nih.gov/33529172
https://pubmed.ncbi.nlm.nih.gov/33529172
Autor:
Florian Krammer, Sarah F. Andrews, Kenta Matsuda, Peter D. Kwong, Stephen A. Migueles, Adam K. Wheatley, Sarah Stuccio, Sam Darko, Marc Gurwith, Mark Connors, Jinghe Huang, Baoshan Zhang, Robert T. Bailer, Trevor Griesman, M. Gordon Joyce, Zizhang Sheng, Jeff Alexander, Alyssa A. Pullano, Elise Ishida, Jason Plyler, Yaroslav Tsybovsky, Byong H. Kang, Teddy John Wohlbold, Hana Golding, Tongqing Zhou, Kwanyee Leung, Richard A. Koup, Jon Smith, Adrian B. McDermott, Surender Khurana, Lyuba Bolkhovitinov, Crystal S.F. Cheung, Cinque Soto, Yongping Yang, Yicheng Guo, Lawrence Shapiro, Veronika Chromikova, C. Jason Liang, Sandeep Narpala, April Poole, Alberto Cagigi
Publikováno v:
Science Immunology. 4
Induction of an antibody response capable of recognizing highly diverse strains is a major obstacle to the development of vaccines for viruses such as HIV and influenza. Here, we report the dynamics of B cell expansion and evolution at the single-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbb70ea554f5cb4b95d0cf15d6facdd
https://doi.org/10.1126/sciimmunol.aau2710
https://doi.org/10.1126/sciimmunol.aau2710