Coordinated Proliferation and Differentiation of Human-Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Depend on Bone Morphogenetic Protein Signaling Regulation by GREMLIN 2.

Autor: Bylund JB; 1 Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee.; 2 Department of Pharmacology, Vanderbilt University School of Medicine , Nashville, Tennessee., Trinh LT; 1 Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee., Awgulewitsch CP; 1 Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee., Paik DT; 1 Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee.; 3 Department of Cell and Developmental Biology, Vanderbilt University School of Medicine , Nashville, Tennessee., Jetter C; 1 Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee., Jha R; 4 Department of Pediatrics, Emory University School of Medicine , Atlanta, Georgia ., Zhang J; 5 Stem Cell and Regenerative Medicine Center, University of Wisconsin School of Medicine and Public Health , Madison, Wisconsin., Nolan K; 6 Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati , Cincinnati, Ohio., Xu C; 4 Department of Pediatrics, Emory University School of Medicine , Atlanta, Georgia ., Thompson TB; 6 Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati , Cincinnati, Ohio., Kamp TJ; 5 Stem Cell and Regenerative Medicine Center, University of Wisconsin School of Medicine and Public Health , Madison, Wisconsin., Hatzopoulos AK; 1 Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee.; 3 Department of Cell and Developmental Biology, Vanderbilt University School of Medicine , Nashville, Tennessee.

Publikováno v: Stem cells and development [Stem Cells Dev] 2017 May 01; Vol. 26 (9), pp. 678-693. Date of Electronic Publication: 2017 Mar 20.

Differentiation of Atrial Cardiomyocytes from Pluripotent Stem Cells Using the BMP Antagonist Grem2.

Autor: Bylund JB; Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University School of Medicine; Department of Pharmacology, Vanderbilt University., Hatzopoulos AK; Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University School of Medicine; Department of Cell & Developmental Biology, Vanderbilt University School of Medicine; antonis.hatzopoulos@vanderbilt.edu.

Publikováno v: Journal of visualized experiments : JoVE [J Vis Exp] 2016 Mar 10 (109). Date of Electronic Publication: 2016 Mar 10.