Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Byeong-Won Kim"'
Autor:
Eunyoung Park, Shaun Rawson, Anna Schmoker, Byeong-Won Kim, Sehee Oh, Kangkang Song, Hyesung Jeon, Michael J. Eck
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract RAF-family kinases are activated by recruitment to the plasma membrane by GTP-bound RAS, whereupon they initiate signaling through the MAP kinase cascade. Prior structural studies of KRAS with RAF have focused on the isolated RAS-binding and
Externí odkaz:
https://doaj.org/article/024f9e85bb9c4c38ad6050e31be70692
Autor:
Eunyoung Park, Shaun Rawson, Anna Schmoker, Byeong-Won Kim, Sehee Oh, Kangkang Song, Hyesung Jeon, Michael J. Eck
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/f878864051f7492aada23cea4aaae674
Autor:
Woo Sung Kim, Hee Do Chae, Inji Jung, Won-Kyu Lee, Woo Jun Lee, Jisun Lee, Yejin Gong, Dohyun Lee, Byeong-Won Kim, Jin-Koo Kim, Jaehyeon Hwang, Dae-Hyuk Kweon, Sang Taek Jung, Jung-Hyun Na
Publikováno v:
Fish & Shellfish Immunology. 138:108807
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::351fce7b4d6981bf9099bff985c42196
https://doi.org/10.1016/j.fsi.2023.108807
https://doi.org/10.1016/j.fsi.2023.108807
Autor:
Eunyoung Park, Shaun Rawson, Anna Schmoker, Byeong-Won Kim, Sehee Oh, KangKang Song, Hyesung Jeon, Michael Eck
Cryo-EM structures of a KRAS/BRAF/MEK1/14-3-3 complex reveal KRAS bound to the flexible Ras-binding domain of BRAF, captured in two orientations. Autoinhibitory interactions are unperturbed by binding of KRAS and in vitro activation studies confirm t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e1105ca1938ebdc6352bdfccaf6105
https://doi.org/10.1101/2022.07.14.500081
https://doi.org/10.1101/2022.07.14.500081
Autor:
Kunhua Li, Byeong-Won Kim, Gonzalo Gonzalez-Del Pino, Scott B. Ficarro, Eun Young Park, Hyesung Jeon, Humayun Sharif, Michael J. Eck, Shaun Rawson, Jarrod A. Marto
Publikováno v:
Nature
RAF family kinases are RAS-activated switches that initiate signalling through the MAP kinase cascade to control cellular proliferation, differentiation and survival1–3. RAF activity is tightly regulated and inappropriate activation is a frequent c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7471b638f7afe65a417ed08a0686c9
http://europepmc.org/articles/PMC7014971
http://europepmc.org/articles/PMC7014971
Autor:
Juneyoung Jung, Ick Young Kim, Jiyea Kim, Hyun Kyu Song, Seongman Kang, Byeong Won Kim, Jun Hoe Kim, Yunjung Jin, Joungmok Kim, Heesun Cheong
The initiation of macroautophagy/autophagy is tightly regulated by the upstream ULK1 kinase complex, which affects many downstream factors including the PtdIns3K complex. The phosphorylation of the right position at the right time on downstream molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e954e057c582a2a10e008a59bc0475a
Autor:
Kyung Hye Roh, Hyun Kyu Song, Eui Ju Choi, Leehyeon Kim, Byeong Won Kim, Jun Hoe Kim, Do Hoon Kwon
Publikováno v:
Biochemical and biophysical research communications. 490(3)
LC3-family member proteins play a critical role in autophagy, a cellular process responsible for the degradation of massive cellular components including intracellular pathogens. A variety of molecules involved in the autophagic pathway engage in spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945023d81ffc81d29b4c9692753d7acf
https://pubmed.ncbi.nlm.nih.gov/28668392
https://pubmed.ncbi.nlm.nih.gov/28668392
Autor:
Do Hoon Kwon, Leehyeon Kim, Yong Boo Kuk, Byeong Won Kim, Min Kyung Kim, Jun Hoe Kim, Bong Heon Kim, Hyun Kyu Song, Woo Seok Yang, Sun Joo Oh, Si Hoon Park, Yang Ouk Jung
Publikováno v:
SCIENTIFIC REPORTS(7)
Scientific Reports
Scientific Reports
The coiled-coil (CC) domain is a very important structural unit of proteins that plays critical roles in various biological functions. The major oligomeric state of CCs is a dimer, which can be either parallel or antiparallel. The orientation of each
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddda2b6ca791b150c24fa9ac5f604261
https://doi.org/10.1038/srep43318
https://doi.org/10.1038/srep43318
Autor:
Woo Cheol Lee, Leehyeon Kim, Byeong Won Kim, Hyun Kyu Song, Kwang Yeon Hwang, Sulhee Kim, Ju Han Song, Do Hoon Kwon, Yang Ouk Jung, In Young Lee, Seung Beom Hong, Eui Ju Choi, Kyung Hye Roh
Hosts utilize macroautophagy/autophagy to clear invading bacteria; however, bacteria have also developed a specific mechanism to survive by manipulating the host cell autophagy mechanism. One pathogen, Legionella pneumophila, can hinder host cell aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a9d6afabef8003eb92bf313d0a5d2d
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 68:1409-1417
Autophagy is a regulated degradation pathway that plays a critical role in all eukaryotic life cycles. One interesting feature of the core autophagic process, autophagosome formation, is similar to ubiquitination. One of two autophagic E2 enzymes, At
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8544a2d6676b50c1b5928d37b06534fd
https://doi.org/10.1107/s0907444912034166
https://doi.org/10.1107/s0907444912034166