Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Byeong ill Lee"'
Autor:
Jiyu Lee, Byeong ill Lee, Jangmi Choi, Yuri Park, Seo-Jin Park, Minjae Park, Jeong-Hyeon Lim, Sangsoo Hwang, Jeong-Min Lee, Young G. Shin
Publikováno v:
Molecules, Vol 27, Iss 23, p 8612 (2022)
The purpose of this study is to investigate the difference of in vitro–in vivo correlation of α-amanitin from clearance perspectives as well as to explore the possibility of extra-hepatic metabolism of α-amanitin. First, a liquid chromatography-q
Externí odkaz:
https://doaj.org/article/8e4c1c28c24543cbac154f2611426b8b
Autor:
Minjae Park, Byeong Ill Lee, Jangmi Choi, Yuri Park, Seo-Jin Park, Jeong-Hyeon Lim, Jiyu Lee, Young G. Shin
Publikováno v:
Molecules, Vol 27, Iss 6, p 2011 (2022)
Daporinad (FK866) is one of the highly specific inhibitors of nicotinamide phosphoribosyl transferase (NAMPT) and known to have its unique mechanism of action that induces the tumor cell apoptosis. In this study, a simple and sensitive liquid chromat
Externí odkaz:
https://doaj.org/article/bba79c267d424cca90f6bd7c769dcbe3
Autor:
Seo-jin Park, Byeong ill Lee, Min-Ho Park, Jangmi Choi, Yuri Park, Min-jae Park, Jeong-hyeon Lim, Jiyu Lee, Sangsoo Hwang, Jeongmin Lee, Young G. Shin
Publikováno v:
Applied Sciences, Vol 11, Iss 20, p 9437 (2021)
Trastuzumab emtansine (T-DM1, brand name: Kadcyla®) is the first FDA-approved antibody-drug conjugate (ADC) for metastatic human epidermal growth factor receptor 2 positive (HER2+) breast cancer. It consists of three components: trastuzumab, an anti
Externí odkaz:
https://doaj.org/article/066a6efbfb3247288f5d3129c8490d40
Autor:
Jangmi Choi, Min-Ho Park, Seok-Ho Shin, Jin-Ju Byeon, Byeong ill Lee, Yuri Park, Young G. Shin
Publikováno v:
Molecules, Vol 26, Iss 4, p 1179 (2021)
Sulfasalazine (SAS), an anti-inflammatory drug with potent cysteine/glutamate antiporter system xc-(SXC) inhibition has recently shown beneficial effects in brain-related diseases. Despite many reports related to central nervous system (CNS) effect o
Externí odkaz:
https://doaj.org/article/088dd43cd10944599185e7adb41d7059
Autor:
Byeong ill Lee, Seo-jin Park, Yuri Park, Seok-Ho Shin, Jang-mi Choi, Min-jae Park, Jeong-hyeon Lim, Sun Young Kim, Hyangsook Lee, Young G. Shin
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 125 (2021)
Antibody–drug conjugate (ADC) linkers play an important role in determining the safety and efficacy of ADC. The Ortho Hydroxy-Protected Aryl Sulfate (OHPAS) linker is a newly developed linker in the form of a di-aryl sulfate structure consisting of
Externí odkaz:
https://doaj.org/article/c764a0611c8143839f33fc26110c4018
Autor:
Seok-Ho Shin, Yuri Park, Min-Ho Park, Jin-Ju Byeon, Byeong ill Lee, Jangmi Choi, Young G. Shin
Publikováno v:
Life, Vol 10, Iss 7, p 115 (2020)
Neuro–inflammation is known to be one of the pathogenesis for the degenerative central nervous system (CNS) disease. Recently various approaches for the treatment of brain diseases by controlling neuro-inflammation in the brain have been introduced
Externí odkaz:
https://doaj.org/article/48f37666c46544e2bb516d7c43666f01
Autor:
Yuri Park, Min-Ho Park, Jin-Ju Byeon, Seok-Ho Shin, Byeong ill Lee, Jang-mi Choi, Nahye Kim, Seo-jin Park, Min-jae Park, Jeong-hyeon Lim, Young G. Shin
Publikováno v:
Molecules, Vol 25, Iss 9, p 2209 (2020)
5-Amino-7-(2-phenylethyl)-2-(2-furyl)-pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c) pyrimidine (SCH 58261) is one of the new chemical entities that has been developed as an adenosine A2A receptor antagonist. Although SCH 58261 has been reported to be benefic
Externí odkaz:
https://doaj.org/article/a2fbfb7bd6f649149d82cd8f281da431
Autor:
Byeong ill Lee, Min-Ho Park, Jin-Ju Byeon, Seok-Ho Shin, Jangmi Choi, Yuri Park, Yun-Hee Park, Jeiwook Chae, Young G. Shin
Publikováno v:
Molecules, Vol 25, Iss 7, p 1515 (2020)
The novel prenyl transferase-mediated, site-specific, antibody−drug conjugate LCB14-0110 is comprised of a proprietary beta-glucuronide linker and a payload (Monomethyl auristatin F, MMAF, an inhibitor for tubulin polymerization) attached to human
Externí odkaz:
https://doaj.org/article/670d518cadb940d9a7df2aeaa3297888
Autor:
Jin-Ju Byeon, Min-Ho Park, Seok-Ho Shin, Yuri Park, Byeong ill Lee, Jang-mi Choi, Nahye Kim, Seo-jin Park, Min-jae Park, Jeong-hyeon Lim, Young-Guk Na, Young G. Shin
Publikováno v:
Molecules, Vol 25, Iss 5, p 1106 (2020)
Parkinson’s disease is one of the most common neurodegenerative diseases. Adenosine regulates the response to other neurotransmitters in the brain regions related to motor function. In the several subtypes of adenosine receptors, especially, adenos
Externí odkaz:
https://doaj.org/article/a4b7679f09f4470ebb9c6dbc11c0aaa5
Autor:
Min-Ho Park, Byeong ill Lee, Jin-Ju Byeon, Seok-Ho Shin, Jangmi Choi, Yuri Park, Young G. Shin
Publikováno v:
Molecules, Vol 24, Iss 15, p 2754 (2019)
A simple liquid chromatography−quadrupole-time-of-flight−mass spectrometric assay (LC-TOF-MS/MS) has been developed for the evaluation of metabolism and pharmacokinetic (PK) characteristics of monomethyl auristatin F (MMAF) in rat, which is being
Externí odkaz:
https://doaj.org/article/1937c08029fd4848b762197dda7acf70