Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Byeong Mo Kim"'
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-26 (2024)
Abstract Alzheimer’s disease (AD) is the most prevalent form of dementia in the elderly and represents a major clinical challenge in the ageing society. Neuropathological hallmarks of AD include neurofibrillary tangles composed of hyperphosphorylat
Externí odkaz:
https://doaj.org/article/ae372be1bc6e41c18c455cd52796feca
Autor:
Byeong Mo Kim, Yunkyung Hong, Seunghoon Lee, Pengda Liu, Ji Hong Lim, Yong Heon Lee, Tae Ho Lee, Kyu Tae Chang, Yonggeun Hong
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 11, Pp 26880-26913 (2015)
Ionizing radiation (IR), such as X-rays and gamma (γ)-rays, mediates various forms of cancer cell death such as apoptosis, necrosis, autophagy, mitotic catastrophe, and senescence. Among them, apoptosis and mitotic catastrophe are the main mechanism
Externí odkaz:
https://doaj.org/article/9b05209f09724ce0bd04069b59862761
Autor:
Chun-Hau Chen, Wenzong Li, Rukhsana Sultana, Mi-Hyeon You, Asami Kondo, Koorosh Shahpasand, Byeong Mo Kim, Man-Li Luo, Morris Nechama, Yu-Min Lin, Yandan Yao, Tae Ho Lee, Xiao Zhen Zhou, Aaron M. Swomley, D. Allan Butterfield, Yan Zhang, Kun Ping Lu
Publikováno v:
Neurobiology of Disease, Vol 76, Iss , Pp 13-23 (2015)
The unique proline isomerase Pin1 is pivotal for protecting against age-dependent neurodegeneration in Alzheimer's disease (AD), with its inhibition providing a molecular link between tangle and plaque pathologies. Pin1 is oxidatively modified in hum
Externí odkaz:
https://doaj.org/article/d411781e221e406fa456c9193b66ddf6
Autor:
Yoon-Mi Lee, Geon-Hee Kim, Eun-Ji Park, Taek-In Oh, Sujin Lee, Sang-Yeon Kan, Hyeji Kang, Byeong Mo Kim, Ji Hyung Kim, Ji-Hong Lim
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1092 (2019)
Several reports have shown that thymoquinone (TQ) effectively attenuates angiogenesis in cancer cells, resulting in suppression of tumor growth. However, it is not yet clear whether TQ reduces hypoxia-inducible factor-1α (HIF-1α) expression in hypo
Externí odkaz:
https://doaj.org/article/d8efcea2266541088b33dad765037457
Publikováno v:
Genomics & Informatics, Vol 11, Iss 4, Pp 245-253 (2013)
A radioresistant cell line was established by fractionated ionizing radiation (IR) and assessed by a clonogenic assay, flow cytometry, and Western blot analysis, as well as zymography and a wound healing assay. Microarray was performed to profile glo
Externí odkaz:
https://doaj.org/article/4ecd59611df04560945f14fe50a7226e
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3428 (2018)
YAP/TAZ, a transcriptional co-activator of Hippo pathway, has emerged as a central player in vessel homeostasis such as sprouting angiogenesis and vascular barrier stabilization, during development. However, the role of YAP/TAZ in pathological angiog
Externí odkaz:
https://doaj.org/article/3bfde03ded8546eba6c9ed8b9da4cb80
Autor:
Young-Seon Kim, Yoon-Mi Lee, Taek-In Oh, Dong Hoon Shin, Geon-Hee Kim, Sang-Yeon Kan, Hyeji Kang, Ji Hyung Kim, Byeong Mo Kim, Woo Jong Yim, Ji-Hong Lim
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3127 (2018)
Reduced therapeutic efficacy of sorafenib, a first-generation multikinase inhibitor, is often observed during the treatment of advanced hepatocellular carcinoma (HCC). Emodin is an active component of Chinese herbs, and is effective against leukemia,
Externí odkaz:
https://doaj.org/article/a08602cab69b4488bf5792ce9a48f9bf
Autor:
Taek-In Oh, Jun Ho Lee, Seongman Kim, Taek-Jin Nam, Young-Seon Kim, Byeong Mo Kim, Woo Jong Yim, Ji-Hong Lim
Publikováno v:
Molecules, Vol 23, Iss 1, p 42 (2017)
Fascaplysin, a natural product isolated from marine sponges, is a potential candidate for the development of anti-cancer drugs. However, the mechanism underlying its therapeutic effect of strengthening anti-cancer efficacy of other drugs is poorly un
Externí odkaz:
https://doaj.org/article/816353b47a0a44df87a8f8a303ca77f0
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 3, p 532 (2017)
Recent studies have shown that vanillin has anti-cancer, anti-mutagenic, and anti-metastatic activity; however, the precise molecular mechanism whereby vanillin inhibits metastasis and cancer progression is not fully elucidated. In this study, we exa
Externí odkaz:
https://doaj.org/article/c54d9e3398554f7e951a0af7e0a44013
Publikováno v:
Annals of Oncology. 29:2010-2017
Background In contrast to its well-known endocrine function, the role of inhibin in cancer development and therapeutic response is unclear. Salmonella, particularly less toxic attenuated Salmonella strains, are used to treat cancer in two ways. First