LIM-only protein FHL2 attenuates vascular tissue factor activity, inhibits thrombus formation in mice and FHL2 genetic variation associates with human venous thrombosis

Autor: Kroone, C., Vos, M., Rademakers, T., Kuijpers, M., Hoogenboezem, M., Buul, J. van, Heemskerk, J.W.M., Ruf, W., Vlieg, A.V., Versteeg, H.H., Goumans, M.J., Vries, C.J.M. de, Kurakula, K., INVENT Consortium

Publikováno v: Haematologica-the Hematology Journal, 105(6), 1677-1685. Ferrata Storti Foundation
Haematologica
Haematologica, 105(6), 1677-1685. Ferrata Storti Foundation
INVENT Consortium 2020, ' LIM-only protein FHL2 attenuates vascular tissue factor activity, inhibits thrombus formation in mice and FHL2 genetic variation associates with human venous thrombosis ', Haematologica, vol. 105, no. 6, pp. 1677-1685 . https://doi.org/10.3324/haematol.2018.203026
Haematologica, 105(6), 1677-1685. FERRATA STORTI FOUNDATION

Bleeding disorders and thrombotic complications are major causes of morbidity and mortality with many cases being unexplained. Thrombus formation involves aberrant expression and activation of tissue factor in vascular endothelial and smooth muscle c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65af7c6088a0497b4a3908d34cbe4ca5
https://doi.org/10.3324/haematol.2018.203026