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We (Riedel et al. Nature 2015), as well as others, have showed that some enzymes exhibit enhanced diffusion when active. In a recent PRL, (Golestanian, PRL 2015, arXiv:1508.03219) R.Golestanian theoretically examines a number of possible explanations
Externí odkaz:
http://arxiv.org/abs/1608.05433
Publikováno v:
Proc. Natl. Acad. Sci. USA 107, 15431-6 (2010)
Accurate knowledge of the thermodynamic properties of nucleic acids is crucial to predicting their structure and stability. To date most measurements of base-pair free energies in DNA are obtained in thermal denaturation experiments, which depend on
Externí odkaz:
http://arxiv.org/abs/1010.1188
Autor:
Cardona, A., León, S., Jaramillo, J.S., Montes, C., Valencia, V., Vanegas, J., Bustamante, C., Echeverri, S.
Publikováno v:
In Tectonophysics 6 December 2018 749:88-103
Autor:
Wen, J. -D., Manosas, M., Li, P. T. X., Smith, S. B., Bustamante, C., Ritort, F., Tinoco Jr, I.
Publikováno v:
Biophysical Journal, 92 (2007) 2996-3009
Experimental variables of optical tweezers instrumentation that affect RNA folding/unfolding kinetics were investigated. A model RNA hairpin, P5ab, was attached to two micron-sized beads through hybrid RNA/DNA handles; one bead was trapped by dual-be
Externí odkaz:
http://arxiv.org/abs/0707.0580
Autor:
Manosas, M., Wen, J. -D., Li, P. T. X., Smith, S. B., Bustamante, C., Tinoco, Jr., I., Ritort, F.
Publikováno v:
Biophysical Journal, 92 (2007) 3010-3021
By exerting mechanical force it is possible to unfold/refold RNA molecules one at a time. In a small range of forces, an RNA molecule can hop between the folded and the unfolded state with force-dependent kinetic rates. Here, we introduce a mesoscopi
Externí odkaz:
http://arxiv.org/abs/0707.0662
Publikováno v:
Phys. Rev. Lett. 96, 118301 (2006)
When mixed together, DNA and polyaminoamide (PAMAM) dendrimers form fibers that condense into a compact structure. We use optical tweezers to pull condensed fibers and investigate the decondensation transition by measuring force-extension curves (FEC
Externí odkaz:
http://arxiv.org/abs/cond-mat/0605737
Publikováno v:
Nature, vol. 437 (2005) 231-234
The description of nonequilibrium processes in nano-sized objects, where the typical energies involved are a few times, is increasingly becoming central to disciplines as diverse as condensed-matter physics, materials science, and biophysics. Major r
Externí odkaz:
http://arxiv.org/abs/cond-mat/0512266
Publikováno v:
Physics Today, vol. 58 (2005) 43-48
The interactions of tiny objects with their environment are dominated by thermal fluctuations. Guided by theory and assisted by micromanipulation tools, scientists have begun to study such interactions in detail.
Comment: PDF file, 13 pages. Lon
Comment: PDF file, 13 pages. Lon
Externí odkaz:
http://arxiv.org/abs/cond-mat/0511629
Publikováno v:
PNAS 2002;99 13544-13548
We investigate the work dissipated during the irreversible unfolding of single molecules by mechanical force, using the simplest model necessary to represent experimental data. The model consists of two levels (folded and unfolded states) separated b
Externí odkaz:
http://arxiv.org/abs/physics/0210063