One ring closer to a closure: the crystal structure of the ES 3 hydroxymethylbilane synthase intermediate.

Autor: Bustad HJ; Norwegian Porphyria Centre (NAPOS), Department for Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway., Christie MS; Norwegian Porphyria Centre (NAPOS), Department for Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway., Laitaoja M; Department of Chemistry, University of Eastern Finland, Joensuu, Finland., Aarsand AK; Norwegian Porphyria Centre (NAPOS), Department for Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway.; Norwegian Organization for Quality Improvement of Laboratory Examinations, Haraldsplass Deaconess Hospital, Bergen, Norway., Martinez A; Department of Biomedicine, University of Bergen, Norway., Jänis J; Department of Chemistry, University of Eastern Finland, Joensuu, Finland., Kallio JP; Department of Biomedicine, University of Bergen, Norway.

Publikováno v: The FEBS journal [FEBS J] 2024 Feb; Vol. 291 (3), pp. 510-526. Date of Electronic Publication: 2023 Nov 02.

High-affinity anti-Arc nanobodies provide tools for structural and functional studies.

Autor: Markússon S; Department of Biomedicine, University of Bergen, Bergen, Norway., Hallin EI; Department of Biomedicine, University of Bergen, Bergen, Norway., Bustad HJ; Department of Biomedicine, University of Bergen, Bergen, Norway., Raasakka A; Department of Biomedicine, University of Bergen, Bergen, Norway., Xu J; Department of Biomedicine, University of Bergen, Bergen, Norway., Muruganandam G; VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, Brussels, Belgium.; Department of Bioengineering Sciences, Structural Biology Brussels, Vrije Universiteit Brussel, Brussel, Belgium., Loris R; VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, Brussels, Belgium.; Department of Bioengineering Sciences, Structural Biology Brussels, Vrije Universiteit Brussel, Brussel, Belgium., Martinez A; Department of Biomedicine, University of Bergen, Bergen, Norway., Bramham CR; Department of Biomedicine, University of Bergen, Bergen, Norway., Kursula P; Department of Biomedicine, University of Bergen, Bergen, Norway.; Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Oulu, Finland.

Publikováno v: PloS one [PLoS One] 2022 Jun 07; Vol. 17 (6), pp. e0269281. Date of Electronic Publication: 2022 Jun 07 (Print Publication: 2022).

Arc self-association and formation of virus-like capsids are mediated by an N-terminal helical coil motif.

Autor: Eriksen MS; Department of Biomedicine, University of Bergen, Norway.; KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Norway., Nikolaienko O; Department of Biomedicine, University of Bergen, Norway.; KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Norway., Hallin EI; Department of Biomedicine, University of Bergen, Norway., Grødem S; Department of Biomedicine, University of Bergen, Norway.; KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Norway., Bustad HJ; Department of Biomedicine, University of Bergen, Norway.; KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Norway., Flydal MI; Department of Biomedicine, University of Bergen, Norway.; KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Norway., Merski I; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, MA, USA., Hosokawa T; Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto, Japan., Lascu D; Department of Biomedicine, University of Bergen, Norway.; KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Norway., Akerkar S; Department of Biomedicine, University of Bergen, Norway.; KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Norway., Cuéllar J; Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain., Chambers JJ; Institute for Applied Life Sciences, University of Massachusetts Amherst, MA, USA., O'Connell R; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, MA, USA., Muruganandam G; VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, Brussels, Belgium.; Structural Biology Brussels, Department of Bioengineering Sciences, Vrije Universiteit Brussel, Belgium., Loris R; VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, Brussels, Belgium.; Structural Biology Brussels, Department of Bioengineering Sciences, Vrije Universiteit Brussel, Belgium., Touma C; Faculty of Biochemistry and Molecular Biology & Biocenter Oulu, University of Oulu, Finland., Kanhema T; Department of Biomedicine, University of Bergen, Norway.; KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Norway., Hayashi Y; Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto, Japan., Stratton MM; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, MA, USA., Valpuesta JM; Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain., Kursula P; Department of Biomedicine, University of Bergen, Norway.; Faculty of Biochemistry and Molecular Biology & Biocenter Oulu, University of Oulu, Finland., Martinez A; Department of Biomedicine, University of Bergen, Norway.; KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Norway., Bramham CR; Department of Biomedicine, University of Bergen, Norway.; KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Norway.

Publikováno v: The FEBS journal [FEBS J] 2021 May; Vol. 288 (9), pp. 2930-2955. Date of Electronic Publication: 2020 Nov 28.

Acute Intermittent Porphyria: An Overview of Therapy Developments and Future Perspectives Focusing on Stabilisation of HMBS and Proteostasis Regulators.

Autor: Bustad HJ; Department of Biomedicine, University of Bergen, 5020 Bergen, Norway., Kallio JP; Department of Biomedicine, University of Bergen, 5020 Bergen, Norway., Vorland M; Norwegian Porphyria Centre (NAPOS), Department for Medical Biochemistry and Pharmacology, Haukeland University Hospital, 5021 Bergen, Norway., Fiorentino V; INSERM U1149, Center for Research on Inflammation (CRI), Université de Paris, 75018 Paris, France., Sandberg S; Norwegian Porphyria Centre (NAPOS), Department for Medical Biochemistry and Pharmacology, Haukeland University Hospital, 5021 Bergen, Norway.; Norwegian Organization for Quality Improvement of Laboratory Examinations (Noklus), Haraldsplass Deaconess Hospital, 5009 Bergen, Norway., Schmitt C; INSERM U1149, Center for Research on Inflammation (CRI), Université de Paris, 75018 Paris, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Centre Français des Porphyries, Hôpital Louis Mourier, 92700 Colombes, France., Aarsand AK; Norwegian Porphyria Centre (NAPOS), Department for Medical Biochemistry and Pharmacology, Haukeland University Hospital, 5021 Bergen, Norway.; Norwegian Organization for Quality Improvement of Laboratory Examinations (Noklus), Haraldsplass Deaconess Hospital, 5009 Bergen, Norway., Martinez A; Department of Biomedicine, University of Bergen, 5020 Bergen, Norway.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 12; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 12.

In vitro characterization of six STUB1 variants in spinocerebellar ataxia 16 reveals altered structural properties for the encoded CHIP proteins.

Autor: Pakdaman Y; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Science, University of Bergen, Bergen, Norway., Sanchez-Guixé M; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Kleppe R; K.G. Jebsen Centre for Neuropsychiatric Disorders, Department of Biomedicine, University of Bergen, Bergen, Norway., Erdal S; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Bustad HJ; Department of Biomedicine, University of Bergen, Bergen, Norway., Bjørkhaug L; Department of Biomedical Laboratory Sciences and Chemical Engineering, Western Norway University of Applied Sciences, Bergen, Norway., Haugarvoll K; Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway., Tzoulis C; Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway., Heimdal K; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Knappskog PM; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.; K.G. Jebsen Centre for Neuropsychiatric Disorders, Department of Clinical Science, University of Bergen, Bergen, Norway., Johansson S; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.; K.G. Jebsen Centre for Neuropsychiatric Disorders, Department of Clinical Science, University of Bergen, Bergen, Norway., Aukrust I; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway ingvild.aukrust@helse-bergen.no.; Department of Clinical Science, University of Bergen, Bergen, Norway.

Publikováno v: Bioscience reports [Biosci Rep] 2017 Apr 28; Vol. 37 (2). Date of Electronic Publication: 2017 Apr 28 (Print Publication: 2017).