Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bussaraporn Kunhapan"'
Autor:
Chanin Limwongse, Surakameth Mahasirimongkol, Nopasak Phasukkijwatana, Wichit Suthammarak, Taisei Mushiroda, Bussaraporn Kunhapan, Chayanon Peerapittayamongkol, Chatchawan Srisawat, Yusuke Nakamura, Jim Stankovich, Timothy A. Thornton, Wanicha Chuenkongkaew, Thanyachai Sura, Aung Win Tun, Melanie Bahlo, Russell Thomson, Patcharee Lertrit
Publikováno v:
Human Genetics. 128:39-49
Leber hereditary optic neuropathy (LHON) is the most common mitochondrially inherited disease causing blindness, preferentially in young adult males. Most of the patients carry the G11778A mitochondrial DNA (mtDNA) mutation. However, the marked incom
Autor:
Patcharee Lertrit, Aung Win Tun, Supannee Kaewsutthi, Pratibha Aryal, Wanphen Katanyoo, Bussaraporn Kunhapan, Rochmy Istikharah, Wanicha Chuenkongkaew
Publikováno v:
Experimental eye research. 116
The present study explored variation in the PARL gene as one of the potential nuclear modifiers in the pathogenesis of Leber hereditary optic neuropathy (LHON). Ten exons, their franking introns and 3' UTR of the PARL gene were analysed. Seventeen SN
Autor:
Yutthana Joyjinda, Nopasak Phasukkijwatana, Supannee Kaewsutthi, Aung Win Tun, Patcharee Lertrit, Wanicha Chuenkongkaew, Bussaraporn Kunhapan, Bhoom Suktitipat
Publikováno v:
Investigative ophthalmologyvisual science. 52(7)
PURPOSE: To investigate the role of mitochondrial DNA (mt DNA) background on the expression of Leber hereditary optic neuropathy (LHON) in Southeast Asian carriers of the G11778A mutation. METHODS: Complete mtDNA sequences were analyzed from 53 unrel