Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Busong Wang"'
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Intellectual disabilities are a type of neurodevelopmental disease caused by neurological dysfunction. Their incidence is largely associated with neural development. Astrocytes are the most widely distributed cells in the mammalian brain. Previous st
Externí odkaz:
https://doaj.org/article/de8c6a02ddeb436eb71b561a993774f3
Publikováno v:
Biochemical and Biophysical Research Communications. 585:15-21
NMDAR (N-methyl-d-aspartate receptor) consisted of GluN1 and GluN2, and/or GluN3 subunits. As the obligatory subunit of NMDAR, GluN1 contains variant N-terminal domain (NTD) and C-terminal domain (CTD). The CTD contains allosteric signal and mediates
Publikováno v:
Biomolecules & Therapeutics
Cereblon (CRBN), a substrate receptor of cullin 4-RING E3 ligase (CRL4) regulates the ubiquitination and degradation of c-Jun, mediating the lipopolysaccharide-induced cellular response. However, the upstream signaling pathway that regulates this pro
Publikováno v:
Anti-cancer drugs. 32(3)
The combination of bortezomib (Velcade, PS-341) and lenalidomide (Revlimid) for the treatment of multiple myeloma was proved by USA Food and Drug Administration in 2006. Lenalidomide prevents the proliferation of multiple myeloma cells through bindin