Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Bushra J. Agha"'
Autor:
Russell J. Mumper, Robert L. Susick, Michael Jay, Bushra J. Agha, Erik Pacyniak, Melanie Doyle-Eisele, James E. Huckle, Raymond A. Guilmette, Matthew P. Sadgrove, Marina G.D. Leed, Waylon Weber
Publikováno v:
International journal of radiation biology. 91(7)
Currently two injectable products of diethylenetriaminepentaacetic acid (DTPA) are U.S. Food and Drug Administration (FDA)-approved for decorporation of (241)Am; however, an oral product is considered more amenable in a mass casualty situation. The d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66cd297a2a8e2954d59b06777bbe0922
https://pubmed.ncbi.nlm.nih.gov/25912343
https://pubmed.ncbi.nlm.nih.gov/25912343
Publikováno v:
Journal of Heterocyclic Chemistry. 30:1191-1195
Potassium permanganate oxidation of 1-aryl-5-(4-pyridyl)-1,2,3-triazolines I in a benzene-water two-phase system using the phase-transfer catalyst tetrabutylammonium chloride yields the corresponding 1H-1,2,3-tri-azoles II. However, when the reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ae483f7d8d1054fce0535ca88024d6b
https://doi.org/10.1002/jhet.5570300505
https://doi.org/10.1002/jhet.5570300505
Publikováno v:
Journal of Enzyme Inhibition. 7:275-301
The rational design and synthesis of a series of peptidyl carbamates incorporating a derivatized ornithyl or lysyl residue at the P3 or P4 subsite is described. The derivatized residues were chosen as mimics of desmonsine cross-links ubiquitously fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ead5c32421f1182751e8e512e8545751
https://doi.org/10.3109/14756369309040770
https://doi.org/10.3109/14756369309040770
Autor:
Kiyoshi Tsuji, Masayuki Kato, George A. Digenis, Bushra J. Agha, Abdul-Kareem Abdul-Raheem, William R. Banks
Publikováno v:
Journal of enzyme inhibition. 7(2)
Twenty-six novel peptidyl carbamates and thiocarbamates were synthesized and evaluated as elastase inhibitors. Eighteen compounds inhibited porcine pancreatic elastase, whereas only eleven of the newly synthesized compounds inhibited human leukocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29fc302991061818d08ec53a3051236
https://pubmed.ncbi.nlm.nih.gov/7509866
https://pubmed.ncbi.nlm.nih.gov/7509866
Publikováno v:
Journal of pharmaceutical sciences. 81(3)
The effect of structural variations on the rates of elastase-catalyzed hydrolysis of model carbonate and carbamate esters was studied using HPLC. It is shown that branching in the immediate vicinity of the carbonate or carbamate functionally results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70da699641937b1dee493f6913d676f9
https://pubmed.ncbi.nlm.nih.gov/1640371
https://pubmed.ncbi.nlm.nih.gov/1640371
Publikováno v:
Journal of Medicinal Chemistry. 29:1468-1476
The design and synthesis of 13 novel peptidyl carbamates are described. When tested for inhibitory activity toward porcine pancreatic elastase, trypsin, and chymotrypsin, six compounds were found to specifically inhibit elastase without affecting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680ad840cbe545bc8d5d4f0817c1cbce
https://doi.org/10.1021/jm00158a025
https://doi.org/10.1021/jm00158a025
Publikováno v:
Journal of Pharmaceutical Sciences. 74:482-485
Six carbamate derivatives were tested for inhibitory activity towards porcine pancreatic elastase, trypsin, and chymotrypsin. Only three esters that are isatoic anhydride derivatives were found to inhibit elastase competitively but nonspecifically. K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f30aac5f5e6aa99ef2850d36be1f56
https://doi.org/10.1002/jps.2600740424
https://doi.org/10.1002/jps.2600740424
Publikováno v:
Tetrahedron Letters. 25:2577-2580
Cyclobutanone reacts with diphenyl-1,2,4,5-tetrazine, in alcoholic base and in diethylamine, to give 3,8-diphenyl-6,7-dihydro-1,2-diazocin-4(5H)-one (5) and 4-diethylamino-3,8-diphenyl-6,7-dihydro-1,2-diazocine (8) respectively. With diethylamine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e866b06ced67fd48bf251c2fb97417c1
https://doi.org/10.1016/s0040-4039(01)81235-1
https://doi.org/10.1016/s0040-4039(01)81235-1
Autor:
Bushra J. Agha, Alan Parr, George A. Digenis, Michael Jay, Larry J. Caldwell, Robert M. Beihn, Arthur R. Mlodozeniec
Publikováno v:
Pharmaceutical Research. :80-83
A cyclic somatostatin analog was compared to an iodinated analog of the same compound with respect to organ distribution and biliary excretion in the rat. The cyclic hexapeptide was radiolabeled with either 14C or 131I (tyrosine). Organ distribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49311c1a37f8afc260d6b4ea057d3639
https://doi.org/10.1023/a:1016342812234
https://doi.org/10.1023/a:1016342812234
Autor:
Ya. R. Tymyanskii, E. Lunt, Bushra J. Agha, M. I. Knyazhanskii, A. I. Pyshchev, Alan R. Katritzky, G. Z. de Ville
Publikováno v:
Chemistry of Heterocyclic Compounds. 20:1245-1254
New 1,2-diaryl- and 1,2,6-triarylpyridinium salts, containing various five- and six-membered heteroaromatic substituents in the 1, 2, and 6-positions of the pyridinium ring, were synthesized. New tetra- and hexacyclic compounds were prepared by photo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28af3274266cb26af5317b82d4d76f86
https://doi.org/10.1007/bf00505716
https://doi.org/10.1007/bf00505716