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How J-chain ensures the assembly of immunoglobulin IgM pentamers.

Autor: Giannone C; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy. giannone@mit.edu.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, USA. giannone@mit.edu., Mess X; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., He R; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., Chelazzi MR; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy., Mayer A; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., Bakunts A; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy., Nguyen T; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., Bushman Y; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., Orsi A; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy., Gansen B; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy.; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany., Degano M; Division of Immunology and Infectious Diseases. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy., Buchner J; Technical University Munich, School of Natural Science, Department of Bioscience, Center for Protein Assemblies, Ernst-Otto-Fischer-Strasse 8, 85748, Garching, Germany. johannes.buchner@tum.de., Sitia R; Division of Genetics and Cell Biology. Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Via Olgettina 58, Milan, IT, Italy. sitia.roberto@hsr.it.

Publikováno v: The EMBO journal [EMBO J] 2024 Dec 04. Date of Electronic Publication: 2024 Dec 04.