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Modeling Effects of Variable preBötzinger Complex Network Topology and Cellular Properties on Opioid-Induced Respiratory Depression and Recovery.

Autor: Chou GM; Department of Computer Science, Western Washington University, Bellingham, Washington 98225., Bush NE; Seattle Children's Research Institute, Center for Integrative Brain Research, Seattle, Washington 90101., Phillips RS; Seattle Children's Research Institute, Center for Integrative Brain Research, Seattle, Washington 90101., Baertsch NA; Seattle Children's Research Institute, Center for Integrative Brain Research, Seattle, Washington 90101 nathan.baertsch@seattlechildrens.org harri267@wwu.edu.; Department of Pediatrics, University of Washington, Seattle, Washington 98195.; Department of Physiology and Biophysics, University of Washington, Seattle, Washington 98195., Harris KD; Department of Computer Science, Western Washington University, Bellingham, Washington 98225 nathan.baertsch@seattlechildrens.org harri267@wwu.edu.

Publikováno v: ENeuro [eNeuro] 2024 Mar 07; Vol. 11 (3). Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).

Purinergic signaling mediates neuroglial interactions to modulate sighs.

Autor: Severs LJ; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, 98101, USA. lsevers@fredhutch.org.; Department of Physiology and Biophysics, University of Washington, Seattle, WA, 98195, USA. lsevers@fredhutch.org., Bush NE; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, 98101, USA., Quina LA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, 98101, USA., Hidalgo-Andrade S; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, 98101, USA., Burgraff NJ; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, 98101, USA., Dashevskiy T; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, 98101, USA., Shih AY; Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA, 98101, USA.; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, 98195, USA.; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA., Baertsch NA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, 98101, USA.; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, 98195, USA., Ramirez JM; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, 98101, USA. jan.ramirez@seattlechildrens.org.; Department of Physiology and Biophysics, University of Washington, Seattle, WA, 98195, USA. jan.ramirez@seattlechildrens.org.; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, 98195, USA. jan.ramirez@seattlechildrens.org.; Department of Neurological Surgery, University of Washington School of Medicine, Seattle, WA, 98195, USA. jan.ramirez@seattlechildrens.org.

Publikováno v: Nature communications [Nat Commun] 2023 Aug 31; Vol. 14 (1), pp. 5300. Date of Electronic Publication: 2023 Aug 31.