Assessing the extent and determinants of socioeconomic inequalities in epilepsy in the UK: a systematic review and meta-analysis of evidence.

Autor: Bush KJ; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK. Electronic address: kathryn.bush@newcastle.ac.uk., Cullen E; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Mills S; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Chin RFM; Muir Maxwell Epilepsy Centre, Department of Child Life and Health and the Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., Thomas RH; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Kingston A; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Pickrell WO; Swansea University Medical School, Swansea University, Swansea, UK; Neurology Department, Swansea Bay University Health Board, Morriston Hospital, Swansea, UK., Ramsay SE; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.

Publikováno v: The Lancet. Public health [Lancet Public Health] 2024 Aug; Vol. 9 (8), pp. e614-e628.

Comparative microbiome analysis of beef cattle, the feedyard environment, and airborne particulate matter as a function of probiotic and antibiotic use, and change in pen environment.

Autor: Strickland AH; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX, United States., Murray SA; Department of Veterinary Pathobiology, Texas A&M University, College Station, TX, United States., Vinasco J; Department of Veterinary Pathobiology, Texas A&M University, College Station, TX, United States., Auvermann BW; Texas A&M AgriLife Research and Extension Center at Amarillo, Amarillo, TX, United States., Bush KJ; Texas A&M AgriLife Research and Extension Center at Amarillo, Amarillo, TX, United States., Sawyer JE; Department of Animal Sciences, Texas A&M University, College Station, TX, United States., Scott HM; Department of Veterinary Pathobiology, Texas A&M University, College Station, TX, United States., Norman KN; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX, United States.

Publikováno v: Frontiers in microbiology [Front Microbiol] 2024 Feb 08; Vol. 15, pp. 1348171. Date of Electronic Publication: 2024 Feb 08 (Print Publication: 2024).

Influence of neighborhood-level socioeconomic deprivation and individual socioeconomic position on risk of developing type 2 diabetes in older men: a longitudinal analysis in the British Regional Heart Study cohort.

Autor: Bush KJ; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK kathryn.bush@newcastle.ac.uk., Papacosta AO; Primary Care and Population Health, University College London, London, UK., Lennon LT; Primary Care and Population Health, University College London, London, UK., Rankin J; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Whincup PH; Population Health Research Institute, St George's University of London, London, UK., Wannamethee SG; Primary Care and Population Health, University College London, London, UK., Ramsay SE; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.

Publikováno v: BMJ open diabetes research & care [BMJ Open Diabetes Res Care] 2023 Oct; Vol. 11 (5).

P2-quinazolinones and bis-macrocycles as new templates for next-generation hepatitis C virus NS3/4a protease inhibitors: discovery of MK-2748 and MK-6325.

Autor: Rudd MT; Department of Medicinal Chemistry, Merck Research Laboratories, West Point, PA (USA). michael_rudd@merck.com., Butcher JW, Nguyen KT, McIntyre CJ, Romano JJ, Gilbert KF, Bush KJ, Liverton NJ, Holloway MK, Harper S, Ferrara M, DiFilippo M, Summa V, Swestock J, Fritzen J, Carroll SS, Burlein C, DiMuzio JM, Gates A, Graham DJ, Huang Q, McClain S, McHale C, Stahlhut MW, Black S, Chase R, Soriano A, Fandozzi CM, Taylor A, Trainor N, Olsen DB, Coleman PJ, Ludmerer SW, McCauley JA

Publikováno v: ChemMedChem [ChemMedChem] 2015 Apr; Vol. 10 (4), pp. 727-35. Date of Electronic Publication: 2015 Mar 10.

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor.

Autor: Harper S; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., McCauley JA; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Rudd MT; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Ferrara M; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., DiFilippo M; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., Crescenzi B; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., Koch U; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., Petrocchi A; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., Holloway MK; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Butcher JW; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Romano JJ; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Bush KJ; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Gilbert KF; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., McIntyre CJ; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Nguyen KT; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Nizi E; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., Carroll SS; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Ludmerer SW; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Burlein C; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., DiMuzio JM; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Graham DJ; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., McHale CM; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Stahlhut MW; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Olsen DB; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Monteagudo E; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., Cianetti S; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., Giuliano C; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., Pucci V; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., Trainor N; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Fandozzi CM; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Rowley M; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., Coleman PJ; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Vacca JP; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States., Summa V; Departments of Medicinal Chemistry, Drug Metabolism, and Molecular Modeling, IRBM, Merck Research Laboratories , Rome, Italy., Liverton NJ; Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Chemistry, Modeling and Informatics, Merck Research Laboratories , West Point, Pennsylvania 19486, United States.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2012 Mar 02; Vol. 3 (4), pp. 332-6. Date of Electronic Publication: 2012 Mar 02 (Print Publication: 2012).