Monoallelic pathogenic variants in LEPR do not cause obesity.

Autor: Delplanque J; Inserm/CNRS UMR 1283/8199, Institut Pasteur de Lille, EGID, Lille University Hospital, Lille, France; University of Lille, Lille, France., Le Collen L; Inserm/CNRS UMR 1283/8199, Institut Pasteur de Lille, EGID, Lille University Hospital, Lille, France; University of Lille, Lille, France; Department of Molecular Medicine, Division of Biochemistry, Molecular Biology, Nutrition, Nancy University Hospital, Nancy, France; Department of Metabolism, Nancy University Hospital, Nancy, France., Loiselle H; Inserm/CNRS UMR 1283/8199, Institut Pasteur de Lille, EGID, Lille University Hospital, Lille, France; University of Lille, Lille, France., Leloire A; Inserm/CNRS UMR 1283/8199, Institut Pasteur de Lille, EGID, Lille University Hospital, Lille, France; University of Lille, Lille, France., Toussaint B; Inserm/CNRS UMR 1283/8199, Institut Pasteur de Lille, EGID, Lille University Hospital, Lille, France; University of Lille, Lille, France., Vaillant E; Inserm/CNRS UMR 1283/8199, Institut Pasteur de Lille, EGID, Lille University Hospital, Lille, France; University of Lille, Lille, France., Charpentier G; CERITD (Centre d'Étude et de Recherche pour l'Intensification du Traitement du Diabète), Evry, France., Franc S; CERITD (Centre d'Étude et de Recherche pour l'Intensification du Traitement du Diabète), Evry, France., Balkau B; Paris-Saclay University, Paris-Sud University, University of Versailles Saint-Quentin-en-Yvelines, Center for Research in Epidemiology and Population Health, Inserm U1018 Clinical Epidemiology, Villejuif, France., Marre M; Necker-Enfants Malades Institute, Inserm, University of Paris, Paris, France; Ambroise Paré Clinic, Neuilly-sur-Seine, France., Henriques E; Inserm/CNRS UMR 1283/8199, Institut Pasteur de Lille, EGID, Lille University Hospital, Lille, France; University of Lille, Lille, France., Buse Falay E; Inserm/CNRS UMR 1283/8199, Institut Pasteur de Lille, EGID, Lille University Hospital, Lille, France; University of Lille, Lille, France., Derhourhi M; Inserm/CNRS UMR 1283/8199, Institut Pasteur de Lille, EGID, Lille University Hospital, Lille, France; University of Lille, Lille, France., Froguel P; Inserm/CNRS UMR 1283/8199, Institut Pasteur de Lille, EGID, Lille University Hospital, Lille, France; University of Lille, Lille, France; Department of Metabolism, Imperial College London, Hammersmith Hospital, London, UK. Electronic address: p.froguel@imperial.ac.uk., Bonnefond A; Inserm/CNRS UMR 1283/8199, Institut Pasteur de Lille, EGID, Lille University Hospital, Lille, France; University of Lille, Lille, France; Department of Metabolism, Imperial College London, Hammersmith Hospital, London, UK. Electronic address: amelie.bonnefond@inserm.fr.

Publikováno v: American journal of human genetics [Am J Hum Genet] 2024 Nov 09. Date of Electronic Publication: 2024 Nov 09.