Multi-omics analyses of airway host-microbe interactions in chronic obstructive pulmonary disease identify potential therapeutic interventions.

Autor: Yan Z; Institute of Ecological Sciences, South China Normal University, Guangzhou, China.; Department of Anesthesiology, Nanfang Hospital, Guangdong Provincial Key Laboratory of Proteomics, Southern Medical University, Guangzhou, China., Chen B; Institute of Ecological Sciences, South China Normal University, Guangzhou, China., Yang Y; First Affiliated Hospital of Guangzhou Medical University, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, Guangzhou, China., Yi X; Institute of Ecological Sciences, South China Normal University, Guangzhou, China., Wei M; Institute of Ecological Sciences, South China Normal University, Guangzhou, China., Ecklu-Mensah G; Department of Pediatrics, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Buschmann MM; Department of Pediatrics, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Liu H; Department of Laboratory Medicine, The First Affiliated Hospital of Xiamen University, Xiamen, China., Gao J; Institute of Ecological Sciences, South China Normal University, Guangzhou, China., Liang W; Institute of Ecological Sciences, South China Normal University, Guangzhou, China., Liu X; Institute of Ecological Sciences, South China Normal University, Guangzhou, China., Yang J; Institute of Ecological Sciences, South China Normal University, Guangzhou, China., Ma W; Institute of Statistics and Big Data, Renmin University of China, Beijing, China., Liang Z; First Affiliated Hospital of Guangzhou Medical University, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, Guangzhou, China., Wang F; First Affiliated Hospital of Guangzhou Medical University, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, Guangzhou, China., Chen D; Key Laboratory of Shenzhen Respiratory Diseases, Institute of Shenzhen Respiratory Diseases, Shenzhen People's Hospital, Shenzhen, China., Wang L; Key Laboratory of Shenzhen Respiratory Diseases, Institute of Shenzhen Respiratory Diseases, Shenzhen People's Hospital, Shenzhen, China., Shi W; First Affiliated Hospital of Guangzhou Medical University, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, Guangzhou, China., Stampfli MR; Department of Medicine, Firestone Institute of Respiratory Health at St. Joseph's Healthcare, McMaster University, Hamilton, Ontario, Canada., Li P; Microbiome Research Centre, St. George and Sutherland Clinical School, UNSW, Sydney, New South Wales, Australia., Gong S; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China., Chen X; Department of Obstetrics and Gynecology, First People's Hospital of Foshan, Foshan, China., Shu W; Institute of Ecological Sciences, South China Normal University, Guangzhou, China., El-Omar EM; Microbiome Research Centre, St. George and Sutherland Clinical School, UNSW, Sydney, New South Wales, Australia., Gilbert JA; Department of Pediatrics, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Blaser MJ; Center for Advanced Biotechnology and Medicine, Rutgers University, New Brunswick, NJ, USA., Zhou H; Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China. hzhou@smu.edu.cn., Chen R; Key Laboratory of Shenzhen Respiratory Diseases, Institute of Shenzhen Respiratory Diseases, Shenzhen People's Hospital, Shenzhen, China. chenrc@vip.163.com., Wang Z; Institute of Ecological Sciences, South China Normal University, Guangzhou, China. wangz@m.scnu.edu.cn.

Publikováno v: Nature microbiology [Nat Microbiol] 2022 Sep; Vol. 7 (9), pp. 1361-1375. Date of Electronic Publication: 2022 Aug 22.

Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors.

Autor: Romero-Calvo I; Institute for Genomic & Systems Biology, The University of Chicago, Chicago, Illinois.; Department of Surgery, The University of Chicago Medicine, Chicago, Illinois., Weber CR; Department of Pathology, The University of Chicago Medicine, Chicago, Illinois., Ray M; Institute for Genomic & Systems Biology, The University of Chicago, Chicago, Illinois.; Department of Pathology, The University of Chicago Medicine, Chicago, Illinois., Brown M; Institute for Genomic & Systems Biology, The University of Chicago, Chicago, Illinois.; Department of Surgery, The University of Chicago Medicine, Chicago, Illinois., Kirby K; Institute for Genomic & Systems Biology, The University of Chicago, Chicago, Illinois.; Department of Surgery, The University of Chicago Medicine, Chicago, Illinois., Nandi RK; The Computer Science Department, Division of the Physical Sciences, The University of Chicago, Chicago, Illinois., Long TM; Department of Medicine, The University of Chicago Medicine, Chicago, Illinois., Sparrow SM; Institute for Genomic & Systems Biology, The University of Chicago, Chicago, Illinois.; Department of Medicine, The University of Chicago Medicine, Chicago, Illinois., Ugolkov A; Division of Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.; Center for Development Therapeutics, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, Illinois.; Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois.; Tempus Labs, Chicago, Illinois., Qiang W; Center for Development Therapeutics, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, Illinois.; Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois., Zhang Y; Tempus Labs, Chicago, Illinois., Brunetti T; Institute for Genomic & Systems Biology, The University of Chicago, Chicago, Illinois.; Department of Medicine, The University of Chicago Medicine, Chicago, Illinois., Kindler H; Department of Medicine, The University of Chicago Medicine, Chicago, Illinois., Segal JP; Department of Pathology, The University of Chicago Medicine, Chicago, Illinois., Rzhetsky A; Institute for Genomic & Systems Biology, The University of Chicago, Chicago, Illinois., Mazar AP; Center for Development Therapeutics, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, Illinois.; Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois.; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Buschmann MM; Institute for Genomic & Systems Biology, The University of Chicago, Chicago, Illinois.; Department of Surgery, The University of Chicago Medicine, Chicago, Illinois., Weichselbaum R; Department of Radiation and Cellular Oncology and the Ludwig Center for Metastasis, The University of Chicago Medicine, Chicago, Illinois., Roggin K; Department of Surgery, The University of Chicago Medicine, Chicago, Illinois. kpwhite@uchicago.edu kevin@tempus.com., White KP; Institute for Genomic & Systems Biology, The University of Chicago, Chicago, Illinois. kpwhite@uchicago.edu kevin@tempus.com.; Tempus Labs, Chicago, Illinois.; Institute for Molecular Engineering, The University of Chicago, Chicago, Illinois.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2019 Jan; Vol. 17 (1), pp. 70-83. Date of Electronic Publication: 2018 Aug 31.

Research priorities in cancer cachexia: The University of Rochester Cancer Center NCI Community Oncology Research Program Research Base Symposium on Cancer Cachexia and Sarcopenia.

Autor: Dunne RF; aWilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York bDepartment of Medicine, University of Washington School of Medicine, Seattle, Washington cDepartment of Supportive Care Medicine, City of Hope, Duarte dSchool of Sport and Exercise Science, University of Northern Colorado, Greeley, Colorado eDepartment of Medicine, Brown University, Providence, Rhode Island fDepartment of Medicine, The University of Chicago, Chicago, Ilinois gKaiser Permanente Division of Research, Kaiser Permanente Northern California, Oakland, California, USA., Mustian KM, Garcia JM, Dale W, Hayward R, Roussel B, Buschmann MM, Caan BJ, Cole CL, Fleming FJ, Chakkalakal JV, Linehan DC, Hezel AF, Mohile SG

Publikováno v: Current opinion in supportive and palliative care [Curr Opin Support Palliat Care] 2017 Dec; Vol. 11 (4), pp. 278-286.

ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture.

Autor: Odenwald MA; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA., Choi W; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Buckley A; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Shashikanth N; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Joseph NE; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA.; Department of Pathology, NorthShore University Health System, Evanston, IL 60201, USA., Wang Y; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA., Warren MH; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA., Buschmann MM; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA., Pavlyuk R; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Hildebrand J; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA., Margolis B; Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Fanning AS; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC 27599, USA., Turner JR; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA jrturner@bwh.harvard.edu.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Publikováno v: Journal of cell science [J Cell Sci] 2017 Jan 01; Vol. 130 (1), pp. 243-259. Date of Electronic Publication: 2016 Oct 21.

The role of molecular remodeling in differential regulation of tight junction permeability.

Autor: Turner JR; Department of Pathology, The University of Chicago, 5841 South Maryland, MC1089, Chicago, IL 60637, USA. Electronic address: jrturner@uchicago.edu., Buschmann MM; Department of Pathology, The University of Chicago, 5841 South Maryland, MC1089, Chicago, IL 60637, USA., Romero-Calvo I; Department of Pathology, The University of Chicago, 5841 South Maryland, MC1089, Chicago, IL 60637, USA., Sailer A; Department of Pathology, The University of Chicago, 5841 South Maryland, MC1089, Chicago, IL 60637, USA., Shen L; Department of Pathology, The University of Chicago, 5841 South Maryland, MC1089, Chicago, IL 60637, USA.

Publikováno v: Seminars in cell & developmental biology [Semin Cell Dev Biol] 2014 Dec; Vol. 36, pp. 204-12. Date of Electronic Publication: 2014 Sep 28.