Výsledky vyhledávání - "Busche, Stephan"

Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types

Autor: Ecker, Simone, Chen, Lu, Pancaldi, Vera, Bagger, Frederik O., Fernández, José María, Carrillo de Santa Pau, Enrique, Juan, David, Mann, Alice L., Watt, Stephen, Casale, Francesco Paolo, Sidiropoulos, Nikos, Rapin, Nicolas Philippe Jean-Pierre, Merkel, Angelika, Stunnenberg, Hendrik G, Stegle, Oliver, Frontini, Mattia, Downes, Kate, Pastinen, Tomi, Kuijpers, Taco W, Rico, Daniel, Valencia, Alfonso, Beck, Stephan, Soranzo, Nicole, Paul, Dirk S., Albers, Cornelis A., Amstislavskiy, Vyacheslav, Ashford, Sofie, Bomba, Lorenzo, Bujold, David, Burden, Frances, Busche, Stephan, Caron, Maxime, Chen, Shu-Huang, Cheung, Warren A., Clarke, Laura, Colgiu, Irina, Datta, Avik, Delaneau, Oliver, Elding, Heather, Farrow, Samantha, Garrido-Martín, Diego, Ge, Bing, Guigo, Roderic, Iotchkova, Valentina, Kundu, Kousik, Kwan, Tony, Lambourne, John J., Lowy, Ernesto, Mead, Daniel, Pourfarzad, Farzin, Redensek, Adriana, Rehnstrom, Karola, Rendon, Augusto, Richardson, David M., Risch, Thomas, Rowlston, Sophia, Shao, Xiaojian, Simon, Marie Michelle, Sultan, Marc, Walter, Klaudia, Wilder, Steven P., Yan, Ying, Antonarakis, Stylianos E., Bourque, Guillaume, Dermitzakis, Emmanouil T., Flicek, Paul, Lehrach, Hans, Martens, Joost H A, Yaspo, Marie-Laure, Ouwehand, Willem H.

Publikováno v: Ecker, S, Chen, L, Pancaldi, V, Bagger, F O, Fernández, J M, Carrillo de Santa Pau, E, Juan, D, Mann, A L, Watt, S, Casale, F P, Sidiropoulos, N, Rapin, N P J-P, Merkel, A, Stunnenberg, H G, Stegle, O, Frontini, M, Downes, K, Pastinen, T, Kuijpers, T W, Rico, D, Valencia, A, Beck, S, Soranzo, N, Paul, D S, Albers, C A, Amstislavskiy, V, Ashford, S, Bomba, L, Bujold, D, Burden, F, Busche, S, Caron, M, Chen, S-H, Cheung, W A, Clarke, L, Colgiu, I, Datta, A, Delaneau, O, Elding, H, Farrow, S, Garrido-Martín, D, Ge, B, Guigo, R, Iotchkova, V, Kundu, K, Kwan, T, Lambourne, J J, Lowy, E, Mead, D, Pourfarzad, F, Redensek, A, Rehnstrom, K, Rendon, A, Richardson, D M, Risch, T, Rowlston, S, Shao, X, Simon, M M, Sultan, M, Walter, K, Wilder, S P, Yan, Y, Antonarakis, S E, Bourque, G, Dermitzakis, E T, Flicek, P, Lehrach, H, Martens, J H A, Yaspo, M-L & Ouwehand, W H 2017, ' Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types ', Genome Biology, vol. 18, no. 1, 18 . https://doi.org/10.1186/s13059-017-1156-8

Background: A healthy immune system requires immune cells that adapt rapidly to environmental challenges. This phenotypic plasticity can be mediated by transcriptional and epigenetic variability. Results: We apply a novel analytical approach to measu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2751::5e17eb2f9f30ac1f5d8217647f6c62d7
https://curis.ku.dk/ws/files/181453200/Ecker_2017_Genome_wide_analysis.pdf

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Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants

Autor: Allum, Fiona, Shao, Xiaojian, Guénard, Frédéric, Simon, Marie Michelle, Busche, Stephan, Caron, Maxime, Lambourne, John, Lessard, Julie, Tandre, Karolina, Hedman, Åsa K., Kwan, Tony, Ge, Bing, Rönnblom, Lars, McCarthy, Mark I., Deloukas, Panos, Richmond, Todd, Burgess, Daniel, Spector, Timothy D., Tchernof, André, Marceau, Simon, Lathrop, Mark, Vohl, Marie Claude, Pastinen, Tomi, Grundberg, Elin, Ahmadi, Kourosh R., Ainali, Chrysanthi, Barrett, Amy, Bataille, Veronique, Bell, Jordana T., Buil, Alfonso, Dermitzakis, Emmanouil T., Dimas, Antigone S., Durbin, Richard, Glass, Daniel, Hassanali, Neelam, Ingle, Catherine, Knowles, David, Krestyaninova, Maria, Lindgren, Cecilia M., Lowe, Christopher E., Meduri, Eshwar, Di Meglio, Paola, Min, Josine L., Montgomery, Stephen B., Nestle, Frank O., Nica, Alexandra C., Nisbet, James, O'Rahilly, Stephen, Parts, Leopold, Potter, Simon, Sandling, Johanna, Sekowska, Magdalena, Shin, So Youn, Small, Kerrin S., Soranzo, Nicole, Surdulescu, Gabriela, Travers, Mary E., Tsaprouni, Loukia, Tsoka, Sophia, Wilk, Alicja, Yang, Tsun Po, Zondervan, Krina T.

Publikováno v: Nature Communications
Allum, F, Shao, X, Guénard, F, Simon, M M, Busche, S, Caron, M, Lambourne, J, Lessard, J, Tandre, K, Hedman, Å K, Kwan, T, Ge, B, Rönnblom, L, McCarthy, M I, Deloukas, P, Richmond, T, Burgess, D, Spector, T D, Tchernof, A, Marceau, S, Lathrop, M, Vohl, M C, Pastinen, T, Grundberg, E, Ahmadi, K R, Ainali, C, Barrett, A, Bataille, V, Bell, J T, Buil, A, Dermitzakis, E T, Dimas, A S, Durbin, R, Glass, D, Hassanali, N, Ingle, C, Knowles, D, Krestyaninova, M, Lindgren, C M, Lowe, C E, Meduri, E, Di Meglio, P, Min, J L, Montgomery, S B, Nestle, F O, Nica, A C, Nisbet, J, O'Rahilly, S, Parts, L, Potter, S, Sandling, J, Sekowska, M, Shin, S Y, Small, K S, Soranzo, N, Surdulescu, G, Travers, M E, Tsaprouni, L, Tsoka, S, Wilk, A, Yang, T P & Zondervan, K T 2015, ' Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants ', Nature Communications, vol. 6, 7211 . https://doi.org/10.1038/ncomms8211

Most genome-wide methylation studies (EWAS) of multifactorial disease traits use targeted arrays or enrichment methodologies preferentially covering CpG-dense regions, to characterize sufficiently large samples. To overcome this limitation, we presen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7634922a50a3e1cb9bf09ba13690e6d
http://europepmc.org/articles/PMC4544751

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