Focused ion beam‐scanning electron microscopy links pathological myelin outfoldings to axonal changes in mice lacking Plp1 or Mag

Autor: Steyer, Anna M., Buscham, Tobias J., Lorenz, Charlotta, Hümmert, Sophie, Eichel‐Vogel, Maria A., Schadt, Leonie C., Edgar, Julia M., Köster, Sarah, Möbius, Wiebke, Nave, Klaus‐Armin, Werner, Hauke B.

Publikováno v: Glia

Healthy myelin sheaths consist of multiple compacted membrane layers closely encasing the underlying axon. The ultrastructure of CNS myelin requires specialized structural myelin proteins, including the transmembrane-tetraspan proteolipid protein (PL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88e8dfed0c76258c96c47076f5424a9
https://hdl.handle.net/21.11116/0000-000B-72BF-E21.11116/0000-000B-72C1-A

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Focused ion beam-scanning electron microscopy links pathological myelin outfoldings to axonal changes in mice lacking Plp1 or Mag.

Autor: Steyer AM; Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Electron Microscopy-City Campus, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Buscham TJ; Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Lorenz C; Institute for X-Ray Physics, University of Göttingen, Göttingen, Germany., Hümmert S; Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Eichel-Vogel MA; Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Schadt LC; Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Edgar JM; Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Köster S; Institute for X-Ray Physics, University of Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany., Möbius W; Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Electron Microscopy-City Campus, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany., Nave KA; Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Werner HB; Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.

Publikováno v: Glia [Glia] 2023 Mar; Vol. 71 (3), pp. 509-523. Date of Electronic Publication: 2022 Nov 10.