Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Busch Frank R"'
Publikováno v:
Organic Process Research & Development. 19:1997-2005
Nonbranded/unauthorized vendors had been manufacturing/selling what they described as bosutinib, while the material supplied was actually an isomer of bosutinib. This raised concerns within the worldwide research community around the established cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebb710e1ce6ad0bf1c6e52bc7a27d325
https://doi.org/10.1021/acs.oprd.5b00244
https://doi.org/10.1021/acs.oprd.5b00244
Autor:
Peter Robert Rose, Denis Lynch, David B. Damon, Darragh Breen, Nga M. Do, Busch Frank R, John A. Ragan, Maria M. O’Sullivan, Eric M. Cordi, Joseph A. Mongillo, Brian C. Vanderplas, Jon Blunt, Ruth E. McDermott, Dennis E. Bourassa, Alanya Engtrakul
Publikováno v:
Organic Process Research & Development. 13:186-197
Development of an efficient bond-forming sequence and optimization of reaction conditions are described for the synthesis of CP-945,598-01 (1·HCl), a CB1 antagonist in clinical studies for the treatment of obesity. Reordering of the bond-forming seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83d0f4ddf324d49a16e57d95f896a5f2
https://doi.org/10.1021/op800255j
https://doi.org/10.1021/op800255j
Autor:
Chiara Bezze, Robert A. Singer, Megan McMahon, Mariano Stivanello, Gregory J. Withbroe, Handfield Robert Eugene, Paul E. Concannon, Jason D. McKinley, Timothy J. N. Watson, Lucia Leoni, Busch Frank R
Publikováno v:
Synthetic Communications. 38:441-447
Described here is the synthesis of (1‐(aminomethyl)‐2,3‐dihydro‐1H‐inden‐3‐yl)methanol 1, the previously unidentified impurity found in the synthesis of 2,1 providing a confirmation of the structure. Fabbrica Italiano Sintetici (FIS), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9dcf0aa90dba515a31c7601f9c2c138
https://doi.org/10.1080/00397910701771231
https://doi.org/10.1080/00397910701771231
Autor:
Busch Frank R, Curtis Cui, Mark T. Barrila, James J. Carey, Michel Couturier, Asaf Alimardanov
Publikováno v:
Organic Process Research & Development. 8:834-837
Statistical design of experiments (DOE) was used to rapidly optimize Red-Al reduction of an imide to produce, after deprotection and salt formation, 3,4-isopropylidenedioxypyrrolidine hydrotosylate (1), an intermediate in the synthesis of Ingliforib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::299027c00484d8d0ecdaf42f19b0dac9
https://doi.org/10.1021/op040204q
https://doi.org/10.1021/op040204q
Autor:
Steven J. Brenek, Busch Frank R, Michel Couturier, Joanna Teresa Negri, John L. Tucker, Brian M. Andresen, David J. am Ende, Jeffrey B. Jorgensen, Pascal Dube
Publikováno v:
Organic Process Research & Development. 6:42-48
An efficient four-step sequence has been developed for the synthesis of 3,4-isopropylidenedioxypyrrolidine hydrotosylate starting from inexpensive N-benzylmaleimide. This approach features a novel N-debenzylation procedure that utilizes the correspon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e8dd5678cc3cf5db9deddcd815c495
https://doi.org/10.1021/op0102161
https://doi.org/10.1021/op0102161
Akademický článek
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Akademický článek
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Publikováno v:
Organic Preparations & Procedures International; Feb1992, Vol. 24 Issue 1, p66-67, 2p
Autor:
Mark Ryland Folse
Throughout the World War I era, the United States Marine Corps'efforts to promote their culture of manliness directed attention away from the dangers of war and military life and towards its potential benefits. As a military institution that valued p
