Genomic Selection Signals in Andean Highlanders Reveal Adaptive Placental Metabolic Phenotypes That Are Disrupted in Preeclampsia.

Autor: O'Brien KA; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom (K.A.O., L.M.W.H., H.W.Y., J.L.A., A.P.S., R.B., P.M.D., G.J.B., A.J.M.).; Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine (K.A.O., W.G., T.S.S.), University of California San Diego, La Jolla, CA.; Department of Biomedical Informatics (K.A.O., J.A.H., J.A.S., C.J.M., H.Y., C.G.J.), University of Colorado School of Medicine, Aurora, CO., Gu W; Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine (K.A.O., W.G., T.S.S.), University of California San Diego, La Jolla, CA.; Herbert Wertheim School of Public Health and Longevity Sciences (W.G.), University of California San Diego, La Jolla, CA., Houck JA; Department of Biomedical Informatics (K.A.O., J.A.H., J.A.S., C.J.M., H.Y., C.G.J.), University of Colorado School of Medicine, Aurora, CO.; Department of Obstetrics and Gynecology, Division of Reproductive Sciences (J.A.H., L.G.M.), University of Colorado School of Medicine, Aurora, CO., Holzner LMW; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom (K.A.O., L.M.W.H., H.W.Y., J.L.A., A.P.S., R.B., P.M.D., G.J.B., A.J.M.)., Yung HW; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom (K.A.O., L.M.W.H., H.W.Y., J.L.A., A.P.S., R.B., P.M.D., G.J.B., A.J.M.)., Armstrong JL; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom (K.A.O., L.M.W.H., H.W.Y., J.L.A., A.P.S., R.B., P.M.D., G.J.B., A.J.M.)., Sowton AP; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom (K.A.O., L.M.W.H., H.W.Y., J.L.A., A.P.S., R.B., P.M.D., G.J.B., A.J.M.)., Baxter R; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom (K.A.O., L.M.W.H., H.W.Y., J.L.A., A.P.S., R.B., P.M.D., G.J.B., A.J.M.)., Darwin PM; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom (K.A.O., L.M.W.H., H.W.Y., J.L.A., A.P.S., R.B., P.M.D., G.J.B., A.J.M.)., Toledo-Jaldin L; Department of Obstetrics, Hospital Materno-Infantil, La Paz, Bolivia (L.T.-J., L.L.-V., A.E.M.-M., V.M.-G.)., Lazo-Vega L; Department of Obstetrics, Hospital Materno-Infantil, La Paz, Bolivia (L.T.-J., L.L.-V., A.E.M.-M., V.M.-G.)., Moreno-Aramayo AE; Department of Obstetrics, Hospital Materno-Infantil, La Paz, Bolivia (L.T.-J., L.L.-V., A.E.M.-M., V.M.-G.)., Miranda-Garrido V; Department of Obstetrics, Hospital Materno-Infantil, La Paz, Bolivia (L.T.-J., L.L.-V., A.E.M.-M., V.M.-G.)., Shortt JA; Department of Biomedical Informatics (K.A.O., J.A.H., J.A.S., C.J.M., H.Y., C.G.J.), University of Colorado School of Medicine, Aurora, CO., Matarazzo CJ; Department of Biomedical Informatics (K.A.O., J.A.H., J.A.S., C.J.M., H.Y., C.G.J.), University of Colorado School of Medicine, Aurora, CO., Yasini H; Department of Biomedical Informatics (K.A.O., J.A.H., J.A.S., C.J.M., H.Y., C.G.J.), University of Colorado School of Medicine, Aurora, CO., Burton GJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom (K.A.O., L.M.W.H., H.W.Y., J.L.A., A.P.S., R.B., P.M.D., G.J.B., A.J.M.)., Moore LG; Department of Obstetrics and Gynecology, Division of Reproductive Sciences (J.A.H., L.G.M.), University of Colorado School of Medicine, Aurora, CO., Simonson TS; Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine (K.A.O., W.G., T.S.S.), University of California San Diego, La Jolla, CA., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom (K.A.O., L.M.W.H., H.W.Y., J.L.A., A.P.S., R.B., P.M.D., G.J.B., A.J.M.)., Julian CG; Department of Biomedical Informatics (K.A.O., J.A.H., J.A.S., C.J.M., H.Y., C.G.J.), University of Colorado School of Medicine, Aurora, CO.

Publikováno v: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2024 Feb; Vol. 81 (2), pp. 319-329. Date of Electronic Publication: 2023 Nov 29.

Trophoblast remodeling of the uterine veins and maternal placental blood flow.

Autor: Burton GJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom. Electronic address: gjb2@cam.ac.uk., Moffett A; Department of Pathology, University of Cambridge, Cambridge, United Kingdom.

Publikováno v: American journal of obstetrics and gynecology [Am J Obstet Gynecol] 2023 Dec; Vol. 229 (6), pp. 704-705. Date of Electronic Publication: 2023 Jul 26.

Sphingolipids and acylcarnitines are altered in placentas from women with gestational diabetes mellitus.

Autor: Pinto GDA; LeBioME-Bioactives, Mitochondrial and Placental Metabolism Core, Institute of Nutrition Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil., Murgia A; Department of Biochemistry, Cambridge, UK., Lai C; University of Cagliari, Department of Life and Environmental Science, Cagliari Via Ospedale, Cagliari, Italy., Ferreira CS; LeBioME-Bioactives, Mitochondrial and Placental Metabolism Core, Institute of Nutrition Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil., Goes VA; LeBioME-Bioactives, Mitochondrial and Placental Metabolism Core, Institute of Nutrition Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil., Guimarães DAB; LeBioME-Bioactives, Mitochondrial and Placental Metabolism Core, Institute of Nutrition Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil., Ranquine LG; LeBioME-Bioactives, Mitochondrial and Placental Metabolism Core, Institute of Nutrition Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil., Reis DL; LeBioME-Bioactives, Mitochondrial and Placental Metabolism Core, Institute of Nutrition Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil., Struchiner CJ; School of Applied Mathematics, Fundação Getúlio Vargas, Rio de Janeiro, Brazil.; Institute of Social Medicine, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil., Griffin JL; Department of Biochemistry, Cambridge, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Burton GJ; Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Torres AG; LeBioME-Bioactives, Mitochondrial and Placental Metabolism Core, Institute of Nutrition Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.; Lipid Biochemistry and Lipidomics Laboratory, Department of Chemistry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., El-Bacha T; LeBioME-Bioactives, Mitochondrial and Placental Metabolism Core, Institute of Nutrition Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.; Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Lipid Biochemistry and Lipidomics Laboratory, Department of Chemistry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Publikováno v: The British journal of nutrition [Br J Nutr] 2023 Sep 28; Vol. 130 (6), pp. 921-932. Date of Electronic Publication: 2022 Dec 21.

The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth

Autor: Sandovici I, Georgopoulou A, Pérez-García V, Hufnagel A, López-Tello J, Lam BYH, Schiefer SN, Gaudreau C, Santos F, Hoelle K, Yeo GSH, Burling K, Reiterer M, Fowden AL, Burton GJ, Branco CM, Sferruzzi-Perri AN, Constância M

Publikováno v: DEVELOPMENTAL CELL
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Universitat Rovira i virgili (URV)

In all eutherian mammals, growth of the fetus is dependent upon a functional placenta, but whether and how the latter adapts to putative fetal signals is currently unknown. Here, we demonstrate, through fetal, endothelial, hematopoietic, and trophobl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::efa143e063501c383c680fb70ef3b037
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=3874

Protective Effects from the Ischemic/Hypoxic Stress Induced by Labor in the High-Altitude Tibetan Placenta.

Autor: Tana W; Research Center for High Altitude Medicine, Qinghai University, Xining, 810001, Qinghai, China. tanna.mgl@gmail.com.; Key Laboratory for Application of High-Altitude Medicine in Qinghai Province, Xining, China. tanna.mgl@gmail.com., Noryung T; Research Center for High Altitude Medicine, Qinghai University, Xining, 810001, Qinghai, China.; Qinghai University Affiliated Hospital, Qinghai, 810001, China., Burton GJ; Centre for Trophoblast Research, University of Cambridge, Cambridge, UK., van Patot MT; Fort Collins, CO, USA., Ri-Li G; Research Center for High Altitude Medicine, Qinghai University, Xining, 810001, Qinghai, China.; Key Laboratory for Application of High-Altitude Medicine in Qinghai Province, Xining, China.

Publikováno v: Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2021 Mar; Vol. 28 (3), pp. 659-664. Date of Electronic Publication: 2021 Jan 19.