A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus

Autor: Allen, ER, Krumm, SA, Raghwani, J, Halldorsson, S, Elliott, A, Graham, VA, Koudriakova, E, Harlos, K, Wright, D, Warimwe, GM, Brennan, B, Huiskonen, JT, Dowall, SD, Elliott, RM, Pybus, OG, Burton, DR, Hewson, R, Doores, KJ, Bowden, TA

Publikováno v: Cell Reports, Vol 25, Iss 13, Pp 3750-3758.e4 (2018)
Cell Reports
Allen, E R, Krumm, S A, Raghwani, J, Halldorsson, S, Elliott, A, Graham, V A, Koudriakova, E, Harlos, K, Wright, D, Warimwe, G M, Brennan, B, Huiskonen, J T, Dowall, S D, Elliott, R M, Pybus, O G, Burton, D R, Hewson, R, Doores, K J & Bowden, T A 2018, ' A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus ', Cell Reports, vol. 25, no. 13, pp. 3750-3758.e4 . https://doi.org/10.1016/j.celrep.2018.12.001

Summary The Gn subcomponent of the Gn-Gc assembly that envelopes the human and animal pathogen, Rift Valley fever virus (RVFV), is a primary target of the neutralizing antibody response. To better understand the molecular basis for immune recognition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c65bee51bd01eeed6c6fccd71bc928d3
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