Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Burt M. Sharp"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Large scale human genome wide association studies (GWAS) have identified a growing pool of genes associated with cigarette smoking. One of the most prominent, phosphodiesterase-4B (PDE4B), has been associated with multiple smoking phenotypes
Externí odkaz:
https://doaj.org/article/ded857123e64489eacf2c819689bde95
Autor:
Tristan V de Jong, Yanchao Pan, Pasi Rastas, Daniel Munro, Monika Tutaj, Huda Akil, Chris Benner, Apurva S Chitre, William Chow, Vincenza Colonna, Clifton L Dalgard, Wendy M Demos, Peter A Doris, Erik Garrison, Aron Geurts, Hakan M Gunturkun, Victor Guryev, Thibaut Hourlier, Kerstin Howe, Jun Huang, Ted Kalbfleisch, Panjun Kim, Ling Li, Spencer Mahaffey, Fergal J Martin, Pejman Mohammadi, Ayse Bilge Ozel, Oksana Polesskaya, Michal Pravenec, Pjotr Prins, Jonathan Sebat, Jennifer R Smith, Leah C Solberg Woods, Boris Tabakoff, Alan Tracey, Marcela Uliano-Silva, Flavia Villani, Hongyang Wang, Burt M Sharp, Francesca Telese, Zhihua Jiang, Laura Saba, Xusheng Wang, Terence D Murphy, Abraham A Palmer, Anne E Kwitek, Melinda (Mindy) R Dwinell, Robert W Williams, Jun Z Li, Hao Chen
For over a decade, a large research community has relied on a flawed reference assembly of the genome ofRattus norvegicusknown as Rnor_6.0. The seventh assembly of the rat reference genome4mRatBN7.2, based on the inbred Brown Norway rat, corrects num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::861340d72a1519c031afadb54233c22a
https://doi.org/10.1101/2023.04.13.536694
https://doi.org/10.1101/2023.04.13.536694
Large scale human genome wide association studies (GWAS) have identified a growing pool of genes associated with cigarette smoking. One of the most prominent, phosphodiesterase-4B (PDE4B), has been associated with multiple smoking phenotypes. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93bd593c69a36aee4b2284d25009fd8c
https://doi.org/10.1101/2023.03.07.531588
https://doi.org/10.1101/2023.03.07.531588
Publikováno v:
Genes Brain Behav
The steady rise in prescription opioids such as oxycodone has led to a virulent epidemic of widespread abuse and deaths in the United States; approximately 80% of affected individuals initiate the habitual use of oxycodone by using prescription oral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbbb95da7166e6a34068fc57785871e2
https://pubmed.ncbi.nlm.nih.gov/34459088
https://pubmed.ncbi.nlm.nih.gov/34459088
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86214 (2014)
Classical genetic studies show the heritability of cigarette smoking is 0.4-0.6, and that multiple genes confer susceptibility and resistance to smoking. Despite recent advances in identifying genes associated with smoking behaviors, the major source
Externí odkaz:
https://doaj.org/article/e031caf0d4b84f5197a677afaf5d716d
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Stress is a major determinant of relapse to smoked tobacco. In a rat model, repeated stress during abstinence from nicotine self-administration (SA) results in enhanced reacquisition of nicotine SA, which is dependent on the basolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5df1c20c5079f0c3424602c4adace54f
https://pubmed.ncbi.nlm.nih.gov/33344894
https://pubmed.ncbi.nlm.nih.gov/33344894
Stress is a major determinant of relapse to smoked tobacco. In a rat model, repeated stress during abstinence from nicotine self-administration (SA) results in enhanced reacquisition of nicotine SA, which is dependent on the basolateral amygdala (BLA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe3207f32fa806b81fa82b3c1d785fd5
https://doi.org/10.1101/2020.07.10.197525
https://doi.org/10.1101/2020.07.10.197525
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e44234 (2012)
Adult cigarette smokers usually become dependent on cigarettes during adolescence. Despite recent advances in addiction genetics, little data delineates the genetic factors that account for the vulnerability of humans to smoke tobacco. We studied the
Externí odkaz:
https://doaj.org/article/a821711daee64a26bfae8be04f1c5bcc
Autor:
Burt M. Sharp
Publikováno v:
European Journal of Neuroscience. 50:2247-2254
The amygdala is involved in processing incoming information about rewarding stimuli and emotions that denote danger such as anxiety and fear. Bi-directional neural connections between basolateral amygdala (BLA) and brain regions such as nucleus accum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cae0c15b627e66f643eb824faa1fb4d
https://doi.org/10.1111/ejn.13970
https://doi.org/10.1111/ejn.13970
Autor:
Hao eChen, Zhimin eLiu, Suzhen eGong, Xingjun eWu, William L Taylor, Robert W Williams, Shannon G Matta, Burt M Sharp
Publikováno v:
Frontiers in Neuroscience, Vol 5 (2011)
The cellular heterogeneity of brain poses a particularly thorny issue in genome-wide gene expression studies. Because laser capture microdissection (LCM) enables the precise extraction of a small area of tissue, we combined LCM with neuronal track-tr
Externí odkaz:
https://doaj.org/article/f2e9f682d0c14f1098e41b06fdcfe032