Výsledky vyhledávání - "Burt, Janis M."

Akademický článek

Regulation of Cx37 channel and growth-suppressive properties by phosphorylation

Autor: Jacobsen, Nicole L., Pontifex, Tasha K., Li, Hanjun, Solan, Joell L., Lampe, Paul D., Sorgen, Paul L., Burt, Janis M.

Growth suppression mediated by connexin 37 (Cx37; also known as GJA4) requires interaction between its C-terminus and functional pore-forming domain. Using rat insulinoma cells, we show that Cx37 induces cell death and cell cycle arrest, and slowed c

Externí odkaz: http://hdl.handle.net/10150/625983
http://arizona.openrepository.com/arizona/handle/10150/625983

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Dissertation/ Thesis

Connexin 37 Growth Suppressive Phenotype is Regulated in a Site-Specific, Phosphorylation-Dependent Manner

Autor: Taylor, Samantha-Su Zhimin Donna Irene, Jacobsen, Nicole L., Pontifex, Tasha K., Burt, Janis M.

Connexins support the coordinated function of virtually all tissues in the body through facilitation of intercellular, transmembrane, and intracellular signaling. Connexin 37 (Cx37), which plays a role in vascular development and remodeling, has grow

Externí odkaz: http://hdl.handle.net/10150/625189
http://arizona.openrepository.com/arizona/handle/10150/625189

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Dissertation/ Thesis

Growth Suppression Mechanism of Connexin 37 in Response to Phosphorylation State of the Carboxy Terminus

Autor: Jacobsen, Nicole Lynne, Nelson, Tasha K., Burt, Janis M.

Connexin 37 (Cx37), profoundly suppresses the growth of rat insulinoma (Rin) cells and requires a functional channel. To determine if the CT is necessary for Cx37-mediated growth suppression, a series of deletions and mutations affecting the availabi

Externí odkaz: http://hdl.handle.net/10150/243974

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