Výsledky vyhledávání - "Burst-effect"

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Preparation and evaluation of microspheres with dual polymeric film to minimize burst effect of highly water soluble drug

Autor: Liaqat Ali, Mahmood Ahmad, Usman Minhas, Jawad Ahmad Khan, Muhammad Yousuf, Muhammad Sohail, Khaleeq Anwer

Publikováno v: Journal of Contemporary Pharmacy, Vol 5, Iss 1 (2021)

Double-layered controlled release microspheres of venlafaxine were prepared using ethyl cellulose (EC) as a wall forming hydrophobic polymer. Usually, it is difficult to control initial sudden release of highly water-soluble drugs. In this regard, do

Externí odkaz: https://doaj.org/article/b4bead0fa69044b58d7ead4135ca0358

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Irinotecan-encapsulated double-reverse thermosensitive nanocarrier system for rectal administration

Autor: Fakhar ud Din, Ju Yeon Choi, Dong Wuk Kim, Omer Mustapha, Dong Shik Kim, Raj Kumar Thapa, Sae Kwang Ku, Yu Seok Youn, Kyung Taek Oh, Chul Soon Yong, Jong Oh Kim, Han-Gon Choi

Publikováno v: Drug Delivery, Vol 24, Iss 1, Pp 502-510 (2017)

Intravenously administered for the treatment of rectum cancer, irinotecan produces severe side effects due to very high plasma concentrations. A novel irinotecan-encapsulated double reverse thermosensitive nanocarrier system (DRTN) for rectal adminis

Externí odkaz: https://doaj.org/article/cee4305d71e74738b78c2d36afc0c4bf

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Novel insights on the bottom–up rise strength transfer: investigating massed vs. distributed exercise training

Autor: Tiziana Pietrangelo, Mahdi Hosseinzadeh, Mahta Sardroodian, Danilo Bondi, Mahsa Saffari Aman, Nader Nokhodchi

Publikováno v: Sport Sciences for Health. 18:329-339

The purpose of this study is to investigate the Bottom–Up Rise Strength Transfer (BURST) induced by massed vs. distributed-rehabilitative exercise training. Participants were randomly allocated to one of the 12 weeks massed (MRT) vs. distributed-(D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::736bd32b16d349e03b5cb90f1740b559
https://doi.org/10.1007/s11332-021-00810-2

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Ultrasound-Assisted Emulsification of Roasted Coffee Oil in Complex Coacervates and Real-time Coffee Aroma Release by PTR-ToF–MS

Autor: Fabio Yamashita, Rodolfo Campos Zanin, Samo Smrke, Chahan Yeretzian, Louise Emy Kurozawa

Publikováno v: Food and Bioprocess Technology. 14:1857-1871

Roasted coffee oil (RCO) is rich in volatile organic compounds (VOCs), but the VOCs’ volatility and the presence of unsaturated fatty acids make RCO unstable. The microencapsulation process can extend RCO properties by transforming the liquid RCO i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2dc956ccd8c99581342960f9a3bd5745
https://doi.org/10.1007/s11947-021-02683-2

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Akademický článek

Influence of different formulations and process parameters during the preparation of drug-loaded PLGA microspheres evaluated by multivariate data analysis

Autor: Vysloužil Jakub, Doležel Petr, Kejdušová Martina, Mašková Eliška, Mašek Josef, Lukáč Robert, Košťál Vratislav, Vetchý David, Dvořáčková Kateřina

Publikováno v: Acta Pharmaceutica, Vol 64, Iss 4, Pp 403-417 (2014)

The main objective of this study was to evaluate the influence of the formulation and process parameters on PLGA microparticles containing a practically insoluble model drug (ibuprofen) prepared by the o/w solvent evaporation method. Multivariate dat

Externí odkaz: https://doaj.org/article/19acb2c34684428384b10dd63dde2969

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Akademický článek

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Exploration and Preparation of Patient-specific Ciprofloxacin Implants Drug Delivery System Via 3D Printing Technologies

Autor: Dongyang Fang, Weisan Pan, Sen Qiao, Hao Pan, Haowei Sun, Mengsuo Cui, Xin Li, Lu Li

Publikováno v: Journal of pharmaceutical sciences. 110(11)

A suitable drug-loaded implant delivery system that can effectively release antibacterial drug in the postoperative lesion area and help repair bone infection is very significant in the clinical treatment of bone defect. The work was aimed to investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc59af6686ae2ffaaaf7cb8c62e14998
https://pubmed.ncbi.nlm.nih.gov/34371072

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