Výsledky vyhledávání

Mechanistic target of rapamycin inhition extend cellular lifespan in dendritic cells by preserving mitochondrial function

Autor: Bart Everts, Daniel I. Fritz, Burong Ge, Saritha Beauchamp, Erika L. Pearce, Edward J. Pearce, Eyal Amiel

Publikováno v: The Journal of Immunology

TLR-mediated activation of dendritic cells (DCs) is associated with a metabolic transition in which mitochondrial oxidative phosphorylation is inhibited by endogenously synthesized NO and the cells become committed to glucose and aerobic glycolysis f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da937ad148a638eb19ff086358553c4
https://hdl.handle.net/21.11116/0000-0006-614F-521.11116/0000-0006-6151-1

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Akademický článek

Mechanistic target of rapamycin inhibition extends cellular lifespan in dendritic cells by preserving mitochondrial function.

Autor: Amiel, Eyal^1,2, Everts, Bart³, Fritz, Daniel¹, Beauchamp, Saritha¹, Burong Ge¹, Pearce, Erika L.³, Pearce, Edward J.³ edwardpearce@path.wustl.edu

Publikováno v: Journal of Immunology. 9/15/2014, Vol. 193 Issue 6, p2821-2830. 10p.

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