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pro vyhledávání: '"Burnell R. Brown"'
Autor:
Edward J. Frink, Burnell R. Brown
Publikováno v:
Baillière's Clinical Anaesthesiology. 9:1-14
Summary A major question often asked about sevoflurane is why, if it meets all the needs of the practitioner, was it not introduced earlier? After all, the drug has been around since 1975. Most of the reasons sevoflurane has been somewhat of a ‘lat
Autor:
T. Philip Malan, R. Joseph Isner, Elizabeth A. Brown, Scott E. Morgan, Burnell R. Brown, Edward J. Frink
Publikováno v:
Anesthesiology. 80:1019-1025
BACKGROUND Sevoflurane, a new inhalational anesthetic, is biotransformed, producing peak plasma inorganic fluoride concentrations that may exceed 50 microM. We evaluated plasma inorganic fluoride concentrations with prolonged (> 9 MAC-h) sevoflurane
Autor:
Edward J. Frink, Scott E. Morgan, T. Philip Malan, R. Joseph Isner, Elizabeth A. Brown, Burnell R. Brown
Publikováno v:
Journal of Clinical Anesthesia. 6:239-242
Study Objectives: To evaluate the decomposition of sevoflurane in soda lime during prolonged sevof lurane anesthesia in humans. To evaluate for evidence of renal or hepatotoxicity as a result of exposure to these sevoflurane degradation compounds. De
Autor:
Burnell R. Brown, Edward J. Frink
Publikováno v:
Current Opinion in Anaesthesiology. 6:644-647
Plasma Inorganic Fluoride Levels with Sevoflurane Anesthesia in Morbidly Obese and Nonobese Patients
Publikováno v:
Anesthesia & Analgesia. 76:1333-1337
Administration of several of the inhaled anesthetics result in plasma inorganic fluoride concentrations that are higher in obese compared to nonobese patients. Sevoflurane, a new inhaled anesthetic, is metabolized to inorganic fluoride; however, plas
Autor:
Burnell R. Brown, Edward J. Frink
Publikováno v:
Baillière's Clinical Anaesthesiology. 6:931-952
Publikováno v:
Anesthesia & Analgesia. 74:241-245
We compared blood pressure and heart rate changes in healthy patients during anesthesia with sevoflurane (n = 50) versus isoflurane (n = 25) and the rate of recovery after such anesthesia. After premedication with intravenous administration of midazo
Publikováno v:
Anesthesiology. 76:85-90
Inhalational anesthetics produce differential effects on hepatic blood flow and oxygenation that may impact hepatocellular function and drug clearance. In this investigation, the effects of sevoflurane on hepatic blood flow and oxygenation were compa