Zobrazeno 1 - 10
of 456
pro vyhledávání: '"Burn DJ"'
Autor:
van Eijk, Ruben P. A, Jones, Ashley R., Sproviero, William, Shatunov, Aleksey, Shaw, Pamela J., Leigh, P. Nigel, Young, Carolyn A., Shaw, Christopher E., Mora, Gabriele, Mandrioli, Jessica, Borghero, Giuseppe, Volanti, Paolo, Diekstra, Frank P., van Rheenen, Wouter, Verstraete, Esther, Eijkemans, Marinus J. C, Veldink, Jan H., Chio, Adriano, Al-Chalabi, Ammar, van den Berg, Leonard H., van Es, Michael A, For UKMND-LiCALS and LITALS Study Group: Allen C, Counsell C, Farrin A, Al-Chalabi A, Dickie B, Kelly J, Leigh PN, Murphy CL, Payan C, Reynolds G, Shaw P, Steen IN, Thornhill M, Waters J, Zajicek J, Shaw PJ, Young CA, Morrison KE, Dhariwal S, Hornabrook R, Savage L, Burn DJ, Khoo TK, Dougherty A, Wijesekera L, Ellis CM, Ali R, O'Hanlon K, Panicker J, Pate L, Ray P, Wyatt L, Copeland L, Ealing J, Hamdalla H, Leroi I, Murphy C, O'Keeffe F, Oughton E, Partington L, Paterson P, Rog D, Sathish A, Sexton D, Smith J, Vanek H, Dodds S, Williams TL, Clarke J, Eziefula C, Howard R, Orrell R, Sidle K, Sylvester R, Barrett W, Merritt C, Talbot K, Turner MR, Whatley C, Williams C, Williams J, Cosby C, Hanemann CO, Imam I, Phillips C, Timings L, Crawford SE, Hewamadduma C, Hibberd R, Hollinger H, McDermott C, Mills G, Rafiq M, Taylor A, Waines E, Walsh T, Addison-Jones R, Birt J, Hare M, Majid T, Tortelli R, D'Errico E, Bartolomei I, Barbarossa E, Depau B, Costantino E, D'Amico E, Uncini A, Manzoli C, Quatrale R, Sette E, Montanari E, Merello M, Zarcone D, Mascolo M, Vignolo M, Messina S, Morelli C, Marinou K, Papetti L, Lunetta C, Gorni K, De Cicco D, Pipia C, Sola P, Georgoulopoulou E, Sagnelli A, Tedeschi, Gioacchino, Oggioni G, Nasuelli N, D'Ascenzo C, Cima V, Aiello M, Rizzi R, Rinaldi E, Luigetti M, Conte A, Torzini A, Greco G, Mutani R, Fuda G, Tommasi MA
Publikováno v:
Neurology
Neurology, 89(18), 1915. Lippincott Williams and Wilkins
van Eijk, R P A, Jones, A, Sproviero, W, Shatunov, A, Shaw, P J, Leigh, P N, Young, C A, Shaw, C E, Mora, G, Mandrioli, J, Borghero, G, Volanti, P, Diekstra, F P, van Rheenen, W, Verstraete, E, Eijkemans, M J C, Veldink, J H, Chio, A, Al-Chalabi, A, van den Berg, L H, van Es, M A 2017, ' Meta-analysis of pharmacogenetic interactions in amyotrophic lateral sclerosis clinical trials ', Neurology, vol. 89, no. 18, pp. 1915-1922 . https://doi.org/10.1212/WNL.0000000000004606
Neurology, 89(18), 1915. Lippincott Williams and Wilkins
van Eijk, R P A, Jones, A, Sproviero, W, Shatunov, A, Shaw, P J, Leigh, P N, Young, C A, Shaw, C E, Mora, G, Mandrioli, J, Borghero, G, Volanti, P, Diekstra, F P, van Rheenen, W, Verstraete, E, Eijkemans, M J C, Veldink, J H, Chio, A, Al-Chalabi, A, van den Berg, L H, van Es, M A 2017, ' Meta-analysis of pharmacogenetic interactions in amyotrophic lateral sclerosis clinical trials ', Neurology, vol. 89, no. 18, pp. 1915-1922 . https://doi.org/10.1212/WNL.0000000000004606
OBJECTIVE\ud \ud To assess whether genetic subgroups in recent amyotrophic lateral sclerosis (ALS) trials responded to treatment with lithium carbonate, but that the treatment effect was lost in a large cohort of nonresponders.\ud \ud METHODS\ud \ud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dded91da6e21de00f8bb43da61d2685
http://europepmc.org/articles/PMC5664299
http://europepmc.org/articles/PMC5664299
Autor:
Lawson, RA, Yarnall, AJ, Johnston, F, Duncan, GW, Khoo, TK, Collerton, D, Taylor, JP, Burn, DJ, ICICLE-PD Study Group
BACKGROUND: The quality of life (QoL) of informal caregivers of people with Parkinson's disease (PD) (PwP) can be affected by the caring role. Because of cognitive symptoms and diminished activities of daily living, in addition to the management of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07edf24d74ed21fc7b267fd31f3029a
https://www.repository.cam.ac.uk/handle/1810/274815
https://www.repository.cam.ac.uk/handle/1810/274815
Autor:
Shoeibi, A, Litvan, I, Tolosa, E, del Ser, T, Lee, E, Gomez, JC, Tijero, B, Berganzo, K, de Yebenes, JG, Sendon, JLL, Garcia, G, Buongiorno, MT, Bargallo, N, Burguera, JA, Martinez, I, Ruiz-Martinez, J, Narrativel, I, Vivancos, F, Ybot, I, Aguilar, M, Quilez, P, Boada, M, Lafuente, A, Hernandez, I, Lopez-Lozano, JJ, Mata, M, Kupsch, A, Lipp, A, Ebersbach, G, Schmidt, T, Hahn, K, Heoglinger, G, Hollerhage, M, Oertel, WH, Respondek, G, Stamelou, M, Reichmann, H, Wolz, M, Schneider, C, Klingelhofer, L, Berg, D, Maetzler, W, Srulijes, KK, Ludolph, A, Kassubek, J, Steiger, M, Tyler, K, Burn, DJ, Morris, L, Lees, A, Ling, H, Hauser, R, McClain, T, Truong, D, Jenkins, S, Houghton, D, Ferrara, J, Bordelon, Y, Gratiano, A, Golbe, L, Mark, M, Uitti, R, Gerpen, JV, TAUROS Investigators
Publikováno v:
PARKINSONISM & RELATED DISORDERS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Introduction: To avoid bias and optimize statistical power of disease-modifying therapeutic trials, it is critical to include homogeneous populations with similar rate of progression over time. Patients with Progressive Supranuclear Palsy (PSP)-Parki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::e77b442314a852e1bc100cee9d391168
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=11388
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=11388
Autor:
Firbank, MJ, Yarnall, AJ, Lawson, RA, Duncan, GW, Khoo, TK, Petrides, GS, O’Brien, JT, Barker, Roger Alistair, Maxwell, RJ, Brooks, DJ, Burn, DJ
Publikováno v:
Firbank, M J, Yarnall, A J, Lawson, R A, Duncan, G W, Khoo, T K, Petrides, G S, O'Brien, J T, Barker, R A, Maxwell, R J, Brooks, D J & Burn, D J 2016, ' Cerebral glucose metabolism and cognition in newly diagnosed Parkinson’s disease: ICICLE PD study ', Journal of Neurology, Neurosurgery & Psychiatry . https://doi.org/10.1136/jnnp-2016-313918
This is the final version of the article. It first appeared from BioMed Central via http://dx.doi.org/10.1136/jnnp-2016-313918
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52506caa96cac8f2c0fee129b1392ced
Autor:
Hoogland, J, Boel, JA, de Bie, RMA, Geskus, RB, Schmand, BA, Dalrymple-Alford, JC, Marras, C, Adler, CH, Goldman, JG, Troster, AI, Burn, DJ, Litvan, I, Geurtsen, GJ, Mild, MDSSGV
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society, vol 32, iss 7
Hoogland, J; Boel, JA; de Bie, RMA; Geskus, RB; Schmand, BA; Dalrymple-Alford, JC; et al.(2017). Mild Cognitive Impairment as a Risk Factor for Parkinson's Disease Dementia. MOVEMENT DISORDERS, 32(7), 1056-1065. doi: 10.1002/mds.27002. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/13d4s785
Hoogland, J; Boel, JA; de Bie, RMA; Geskus, RB; Schmand, BA; Dalrymple-Alford, JC; et al.(2017). Mild Cognitive Impairment as a Risk Factor for Parkinson's Disease Dementia. MOVEMENT DISORDERS, 32(7), 1056-1065. doi: 10.1002/mds.27002. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/13d4s785
Background The International Parkinson and Movement Disorders Society criteria for mild cognitive impairment in Parkinson’s disease were recently formulated. Objectives The aim of this international study was to evaluate the predictive validity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62470c3c6fed1917c733a67714966484
https://escholarship.org/uc/item/13d4s785
https://escholarship.org/uc/item/13d4s785
Autor:
Firbank, MJ, Yarnall, AJ, Lawson, RA, Duncan, GW, Khoo, TK, Petrides, GS, O'Brien, JT, Barker, RA, Maxwell, RJ, Brooks, DJ, Burn, DJ
OBJECTIVE: To assess reductions of cerebral glucose metabolism in Parkinson's disease (PD) with 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET), and their associations with cognitive decline. METHODS: FDG-PET was performed on a cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d1cd526e60a87130d9ffa875e2bfcd
Autor:
Hewer, S, Varley, S, Boxer, AL, Paul, E, Williams, DR, Azulay, JP, Benecke, R, Boeve, BF, Bordelon, YM, Miller, B, Burn, DJ, Chan, D, Corvol, JC, Couratier, P, Dayalu, P, Doody, R, Driver-Dunkley, E, Ferrara, J, Golbe, LI, Graff-Radford, NR, Grimes, D, Grossman, M, Gunzler, S, Hillis, AE, Höglinger, G, Honig, L, Lang, A, Lees, A, Litvan, I, Isaacson, SH, Jankovic, J, Jog, MS, Kaufer, DI, Kumar, R, Lafontaine, AL, Leegwater-Kim, J, Lessig, S, Lew, MF, Lipp, A, Lobach, I, Lorenzl, SP, Ludolph, A, Marras, C, McGinnis, S, Mollenhauer, B, Pahwa, R, Panisset, M, Reichmann, H, Roberson, E, Santiago, A, Schneider, L, Tuite, P, Williams, D, Woitalla, D, Womack, KB, Xie, T, Zamrini, E, Zermansky, A, Zesiewicz, TA
Publikováno v:
Hewer, S; Varley, S; Boxer, AL; Paul, E; Williams, DR; Azulay, JP; et al.(2016). Minimal clinically important worsening on the progressive supranuclear Palsy Rating Scale. Movement Disorders, 31(10), 1574-1577. doi: 10.1002/mds.26694. UCSF: Retrieved from: http://www.escholarship.org/uc/item/45r9f3g0
© 2016 2016 International Parkinson and Movement Disorder Society Background: Despite the widespread use of the Progressive Supranuclear Palsy Rating Scale (PSPRS), it is not known what change in this scale is meaningful for patients. Methods: We an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::bebc33020c2bdb3c846c2f0e83639c40
http://www.escholarship.org/uc/item/45r9f3g0
http://www.escholarship.org/uc/item/45r9f3g0
Autor:
Keogh, MJ, Kurzawa-Akanbi, M, Griffin, H, Douroudis, K, Ayers, KL, Hussein, RI, Hudson, G, Pyle, A, Cordell, HJ, Attems, J, McKeith, IG, O'Brien, JT, Burn, DJ, Morris, CM, Thomas, AJ, Chinnery, PF
Dementia with Lewy bodies (DLB) is the second most common form of degenerative dementia. Siblings of affected individuals are at greater risk of developing DLB, but little is known about the underlying genetic basis of the disease. We set out to dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::ba7ef70a599179c7f2cb5a3a089bed6a
https://www.repository.cam.ac.uk/handle/1810/253651
https://www.repository.cam.ac.uk/handle/1810/253651
Autor:
Breen, DP, Nombela, C, Vuono, R, Jones, PS, Fisher, K, Burn, DJ, Brooks, DJ, Reddy, AB, Rowe, JB, Barker, RA
© 2016 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder SocietyBackground: Recent studies have suggested that melatonin—a hormone produced by the pineal gland under cir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fc0d558f991dfd7fb95fa4c59bfc038b
https://kar.kent.ac.uk/78972/1/Breen_et_al-2016-Movement_Disorders.pdf
https://kar.kent.ac.uk/78972/1/Breen_et_al-2016-Movement_Disorders.pdf
Autor:
Pichler I, Del Greco M. F, Gögele M, Lill CM, Bertram L, Do CB, Eriksson N, Foroud T, Myers RH, PD GWAS Consortium, Nalls M, Keller MF, International Parkinson's Disease Genomics Consortium, Wellcome Trust Case Control Consortium 2, Benyamin B, Whitfield JB, Genetics of Iron Status Consortium, Pramstaller PP, Hicks AA, Thompson JR, Minelli C., Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón Sánchez J, Schulte C, Lesage S, Arepalli S, Barker R, Ben Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RM, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Illig T, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Perlmutter JS, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CC, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori Ghanbaria A, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams Gray CH, Winder Rhodes S, Martinez M, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Wood NW, Donnelly P, Barroso I, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Duncanson A, Jankowski J, Markus HS, Mathew CG, Palmer CN, Plomin R, Rautanen A, Sawcer SJ, Trembath RC, Viswanathan AC, Band G, Bellenguez C, Freeman C, Hellenthal G, Giannoulatou E, Pirinen M, Pearson R, Su Z, Vukcevic D, Gwilliam R, Blackburn H, Bumpstead SJ, Dronov S, Gillman M, Hammond N, Jayakumar A, McCann OT, Liddle J, Potter SC, Ravindrarajah R, Ricketts M, Waller M, Weston P, Widaa S, Whittaker P, McCarthy MI, Ouwehand WH, Radhakrishnan A, Sambrook J, Toniolo D, Camaschella C, Metspalu A, Esko T, Gieger C, Ried J, Meitinger T, Oexle K, Winkelmann J, Swinkels D, Vermeulen S, van Duijn C, Broer L, Beilby J, Hui J, Anderson D, Visscher P, Martin N., TRAGLIA, MICHELA
Publikováno v:
Pichler, I, Del Greco, M F, Gögele, M, Lill, C M, Bertram, L, Do, C B, Eriksson, N, Foroud, T, Myers, R H, Benyamin, B, Withfield, J B, Pramstaller, P P, Hicks, A A, Thompson, J R, Minelli, C & Bochdanovits, Z 2013, ' Serum iron levels and the risk of Parkinson disease: a mendelian randomization study ', PLoS Medicine, vol. 10, no. 6, e1001462, pp. 1-13 . https://doi.org/10.1371/journal.pmed.1001462
PLOS Medicine, Vol. 10, No 6 (2013) P. e1001462
PLoS Medicine, 10(6):e1001462, 1-13. Nature Publishing Group
PLoS Medicine, Vol 10, Iss 6, p e1001462 (2013)
PLoS Medicine, 10(6):e1001462, 1-13. Public Library of Science
PLoS medicine, 10(6). Public Library of Science
PLoS Medicine
PLOS Medicine, Vol. 10, No 6 (2013) P. e1001462
PLoS Medicine, 10(6):e1001462, 1-13. Nature Publishing Group
PLoS Medicine, Vol 10, Iss 6, p e1001462 (2013)
PLoS Medicine, 10(6):e1001462, 1-13. Public Library of Science
PLoS medicine, 10(6). Public Library of Science
PLoS Medicine
In this study, Mendelian randomization was used to study genes known to modify iron levels, and the effect of iron on Parkinson's disease (PD) risk was estimated. Based on estimates of the genetic effects on both iron and PD obtained from the largest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1ff83d9ac49e91aea223736fdcdb62
https://hdl.handle.net/11541.2/130162
https://hdl.handle.net/11541.2/130162