IGF1R signaling induces epithelial-mesenchymal plasticity via ITGAV in cutaneous carcinoma.

Autor: Lopez-Cerda, Marta¹ (AUTHOR) mlopezc@idibell.cat, Lorenzo-Sanz, Laura¹ (AUTHOR), da Silva-Diz, Victoria^1,2 (AUTHOR), Llop, Sandra³ (AUTHOR), Penin, Rosa M.⁴ (AUTHOR), Bermejo, Josep Oriol⁵ (AUTHOR), de Goeij-de Haas, Richard⁶ (AUTHOR), Piersma, Sander R.⁶ (AUTHOR), Pham, Thang V.⁶ (AUTHOR), Jimenez, Connie R.⁶ (AUTHOR), Martin-Liberal, Juan³ (AUTHOR) jmartinliberal@iconcologia.net, Muñoz, Purificación¹ (AUTHOR) p.munoz@idibell.cat

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 7/29/2024, Vol. 43 Issue 1, p1-21. 21p.

Loss of E-cadherin Enhances IGF1-IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR Inhibitors.

Autor: Nagle AM; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee Women's Research Institute, Pittsburgh, Pennsylvania., Levine KM; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee Women's Research Institute, Pittsburgh, Pennsylvania.; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania., Tasdemir N; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee Women's Research Institute, Pittsburgh, Pennsylvania., Scott JA; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee Women's Research Institute, Pittsburgh, Pennsylvania., Burlbaugh K; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee Women's Research Institute, Pittsburgh, Pennsylvania., Kehm J; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee Women's Research Institute, Pittsburgh, Pennsylvania., Katz TA; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee Women's Research Institute, Pittsburgh, Pennsylvania.; The Center for Precision Environmental Health, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas., Boone DN; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee Women's Research Institute, Pittsburgh, Pennsylvania.; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania., Jacobsen BM; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Atkinson JM; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee Women's Research Institute, Pittsburgh, Pennsylvania., Oesterreich S; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee Women's Research Institute, Pittsburgh, Pennsylvania.; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania., Lee AV; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania. leeav@upmc.edu.; Women's Cancer Research Center, UPMC Hillman Cancer Center, Magee Women's Research Institute, Pittsburgh, Pennsylvania.; Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2018 Oct 15; Vol. 24 (20), pp. 5165-5177. Date of Electronic Publication: 2018 Jun 25.

Lobular Carcinoma of the Breast: A Comprehensive Review with Translational Insights.

Autor: Batra, Harsh¹ (AUTHOR) hbatra@mdanderson.org, Mouabbi, Jason Aboudi² (AUTHOR) jamouabbi@mdanderson.org, Ding, Qingqing³ (AUTHOR) qqding@mdanderson.org, Sahin, Aysegul A.³ (AUTHOR) asahin@mdanderson.org, Raso, Maria Gabriela¹ (AUTHOR) graso@mdanderson.org

Publikováno v: Cancers. Nov2023, Vol. 15 Issue 22, p5491. 28p.

The Chaperone System in Breast Cancer: Roles and Therapeutic Prospects of the Molecular Chaperones Hsp27, Hsp60, Hsp70, and Hsp90.

Autor: Alberti, Giusi¹ (AUTHOR) giusi.alberti@unipa.it, Vergilio, Giuseppe^1,2 (AUTHOR) ajlmacario@som.umaryland.edu, Paladino, Letizia^1,2 (AUTHOR) letizia.paladino@unipa.it, Barone, Rosario¹ (AUTHOR) francesco.cappello@unipa.it, Cappello, Francesco^1,2 (AUTHOR) fabio.bucchieri@unipa.it, Conway de Macario, Everly³ (AUTHOR) econwaydemacario@som.umaryland.edu, Macario, Alberto J. L.^2,3 (AUTHOR), Bucchieri, Fabio¹ (AUTHOR) francesca.rappa@unipa.it, Rappa, Francesca¹ (AUTHOR)

Publikováno v: International Journal of Molecular Sciences. Jul2022, Vol. 23 Issue 14, p7792-7792. 22p.

Insulin-like growth factor-1 receptor crosstalk with integrins, cadherins, and the tumor microenvironment: sticking points in understanding IGF1R function in cancer.

Autor: Galifi, Christopher A., Wood, Teresa L.

Publikováno v: Endocrine-Related Cancer; Oct2023, Vol. 30 Issue 10, p24-39, 16p