Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Burkhard Tuemmler"'
Autor:
Norman Zinne, Marcus Krueger, Doris Hoeltig, Burkhard Tuemmler, Erin C Boyle, Christian Biancosino, Klaus Hoeffler, Peter Braubach, Taufiek K Rajab, Anatol Ciubotaru, Judith Rohde, Karl-Heinz Waldmann, Axel Haverich
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193168 (2018)
The emergence of multi-drug resistant bacteria threatens to end the era of antibiotics. Drug resistant bacteria have evolved mechanisms to overcome antibiotics at therapeutic doses and further dose increases are not possible due to systemic toxicity.
Externí odkaz:
https://doaj.org/article/c0772a87f5a84cac94a1dfa2ffebc381
Autor:
Yael Pewzner‐Jung, Shaghayegh Tavakoli Tabazavareh, Heike Grassmé, Katrin Anne Becker, Lukasz Japtok, Jörg Steinmann, Tammar Joseph, Stephan Lang, Burkhard Tuemmler, Edward H Schuchman, Alex B Lentsch, Burkhard Kleuser, Michael J Edwards, Anthony H Futerman, Erich Gulbins
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 9, Pp 1205-1214 (2014)
Abstract Cystic fibrosis patients and patients with chronic obstructive pulmonary disease, trauma, burn wound, or patients requiring ventilation are susceptible to severe pulmonary infection by Pseudomonas aeruginosa. Physiological innate defense mec
Externí odkaz:
https://doaj.org/article/55d4097c03cf407d8211159fa40ab68e
Autor:
Leif Tueffers, Aditi Batra, Johannes Zimmermann, João Botelho, Florian Buchholz, Junqi Liao, Nicolás Mendoza Mejía, Antje Munder, Jens Klockgether, Burkhard Tüemmler, Jan Rupp, Hinrich Schulenburg
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT Pseudomonas aeruginosa is a ubiquitous, opportunistic human pathogen. Since it often expresses multidrug resistance, new treatment options are urgently required. Such new treatments are usually assessed with one of the canonical laboratory s
Externí odkaz:
https://doaj.org/article/03e4de67c9534611a14e37d744063dcb
Autor:
Burkhard Tümmler
Cystic fibrosis is a severe ion channel disease of autosomal recessive inheritance that is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. Thanks to continuously improved symptomatic treatment during the la
Autor:
Simon Gräber, Sabine Wege, Lena Gyulumyan, Claudia Rueckes-Nilges, Heike Scheuermann, Heimo Mairbaeurl, Marcus A. Mall, Lutz Naehrlich, Christian Dopfer, Rebecca Hyde, Azadeh Bagheri-Hanson, Sebastian Fischer, Marie Dorda, Burkhard Tuemmler, Stephanie Hirtz
Publikováno v:
Cystic fibrosis.
The combination of the CFTR corrector lumacaftor with the potentiator ivacaftor has recently been approved for the treatment of patients with cystic fibrosis (CF) homozygous for the Phe508del CFTR mutation. The pivotal phase 3 trials examined clinica
Autor:
Gesa Diekmann, Burkhard Tuemmler, Cordula Koerner-Rettberg, Christian Dopfer, Sandra Barth, Isabell Ricklefs, Simon Y. Graeber, Lutz Naehrlich, Mark Wielpuetz, Olaf Sommerburg, Anne Schlegtendal, Matthias V. Kopp, Mirjam Stahl, Marcus A. Mall
Publikováno v:
Cystic fibrosis.
Autor:
Mario Drungowski, Natalie Bertsch, Martin Selke, Doris Hoeltig, Inga Probst, Gerald Reiner, Karl Heinz Waldmann, Burkhard Tuemmler, Gerald Friedrich Gerlach, Ralf Herwig, Hermann Willems
Publikováno v:
Mammalian Genome
Actinobacillus pleuropneumoniae is among the most important pathogens worldwide in pig production. The agent can cause severe economic losses due to decreased performance, acute or chronic pleuropneumonia and an increased incidence of death. Therapeu
Autor:
Klaus Hoeffler, Judith Rohde, Peter Braubach, Anatol Ciubotaru, Axel Haverich, Doris Hoeltig, Norman Zinne, Marcus Krueger, Taufiek Konrad Rajab, Erin C. Boyle, Christian Biancosino, Burkhard Tuemmler, Karl-Heinz Waldmann
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193168 (2018)
PLoS ONE
PLoS ONE
The emergence of multi-drug resistant bacteria threatens to end the era of antibiotics. Drug resistant bacteria have evolved mechanisms to overcome antibiotics at therapeutic doses and further dose increases are not possible due to systemic toxicity.
Autor:
Burkhard Tümmler
Personalized medicine promises that medical decisions, practices and products are tailored to the individual patient. Cystic fibrosis, an inherited disorder of ion transport in exocrine glands, is the first successful example of customized drug devel
Autor:
Burkhard Kleuser, Shaghayegh Tavakoli Tabazavareh, Anthony H. Futerman, Tammar Joseph, Lukasz Japtok, Alex B. Lentsch, Stephan Lang, Michael J. Edwards, Heike Grassmé, Burkhard Tuemmler, Edward H. Schuchman, Yael Pewzner-Jung, Katrin Anne Becker, Jörg Steinmann, Erich Gulbins
Publikováno v:
EMBO Molecular Medicine
Cystic fibrosis patients and patients with chronic obstructive pulmonary disease, trauma, burn wound, or patients requiring ventilation are susceptible to severe pulmonary infection by Pseudomonas aeruginosa. Physiological innate defense mechanisms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9466e4e615641189e19b8b720d9586de
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/37594
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/37594