Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Burkhard Helmke"'
Autor:
Gunhild Mechtersheimer, Cristina R. Antonescu, Shih-Chiang Huang, Albrecht Stenzinger, Burkhard Helmke, Yun-Shao Sung, Martina Kirchner, Lei Zhang
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
The genetic hallmark of epithelioid hemangioma (EH) is the presence of recurrent gene fusions involving FOS and FOSB transcription factors, which occur in one-third of the cases. Certain clinical, pathologic, and genotypic correlations have been desc
Autor:
Lars Burchardt, Inga Flor, Rolf Nimzyk, Meike Spiekermann, Jörn Bullerdiek, Susanne Feidicker, Marc Langenbuch, Andrea Gottlieb, Burkhard Helmke
Publikováno v:
Protoplasma
miRNAs of the largest human miRNA gene cluster at all, i.e., C19MC, are almost exclusively expressed in the placenta. Nevertheless, only little is known about the interindividual variation of their expression and even about possible influence of gest
Autor:
Werner Wosniok, Joern Bullerdiek, Lars Burchardt, Andrea Gottlieb, Burkhard Helmke, Wolfgang Kuepker
BackgroundHigh-mobility group AT-hook 2 (HMGA2)expression can be detected in many embryonic and fetal tissues but becomes down-regulated during postnatal life except for many benign and malignant tumors. In the latter case, its expression has been co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab0ba96545da092a8ef85ef0eaa68ca3
https://doi.org/10.1101/2020.12.07.20245092
https://doi.org/10.1101/2020.12.07.20245092
Publikováno v:
Molecular Cytogenetics
Background Periductal stromal tumors of the breast are exceedingly rare biphasic breast tumors with close morphological relationship to phyllodes tumors. So far, results of genetic analyses on these tumors have not been reported. Case presentation A
Autor:
Ulrich Wolffgang, Fred Saad, Zhe Tian, Veronique Ouellet, Dominique Trudel, Jonathan E. Schmitz, Sami-Ramzi Leyh-Bannurah, Lars Budäus, Markus Graefen, Pierre I. Karakiewicz, Burkhard Helmke, Feryel Azzi
Publikováno v:
Journal of Urology. 203
INTRODUCTION AND OBJECTIVE:A huge barrier to implement computational pathology grading constitutes great effort of manual patch annotation within digitized tissue images for training and validation...
Autor:
Jörn Bullerdiek, Burkhard Helmke, Carsten Holzmann, Christian Saager, Gunhild Mechtersheimer, Dirk Koczan
Publikováno v:
Oncotarget
A 50 year old woman underwent laparoscopic supracervical hysterectomy because of symptomatic fibroids. Histologic examination of samples obtained after morcellation revealed typical uterine leiomyomas in all samples investigated. 28 and 47 months lat
Publikováno v:
Oncotarget
Uterine leiomyomas (UL) are the most prevalent symptomatic human tumors at all and somatic mutations of the gene encoding mediator subcomplex 12 (MED12) constitute the most frequent driver mutations in UL. Recently, a rapid loss of mutated cells duri
Publikováno v:
In vivo (Athens, Greece). 34(1)
Our insights into the molecular pathogenesis of uterine smooth muscle tumors have improved significantly. Accordingly, in the present review, we advocate a more refined risk assessment for patients considering surgical removal of fibroids or hysterec
Autor:
Werner Wosniok, Jörn Bullerdiek, Gazanfer Belge, Kathrin Günther, Käte Burchardt, Burkhard Helmke, Andrea Gottlieb, Lars Kloth, Thomas Löning
Publikováno v:
The Journal of Pathology: Clinical Research. 1:239-251
The group of postpubertal testicular germ cell tumours encompasses lesions with highly diverse differentiation – seminomas, embryonal carcinomas, yolk sac tumours, teratomas and choriocarcinomas. Heterogeneous differentiation is often present withi
Autor:
Elisabeth Davioud-Charvet, Ronald Gust, Andreas Unterberg, Katja Becker, Katalin Tóth, Jennifer Lohr, Rezvan Ahmadi, Burkhard Helmke, Valérie Deborde, Mohammad Farhadi, Sebastian Kehr, Christel Herold-Mende, Esther Jortzik, Régis Réau, Ingo Ott
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1844:1415-1426
Glioblastoma, an aggressive brain tumor, has a poor prognosis and a high risk of recurrence. An improved chemotherapeutic approach is required to complement radiation therapy. Gold(I) complexes bearing phosphole ligands are promising agents in the tr