Zobrazeno 1 - 10
of 560
pro vyhledávání: '"Burkhard Göke"'
Autor:
Christoph J. Auernhammer, Christine Spitzweg, Burkhard Göke, Johannes N. Hoffmann, Karin A. Herrmann, Alexander Haug, Michael Vogeser, Axel Kuttner, Michael Lauseker, Svenja Nölting
Publikováno v:
Cancers, Vol 4, Iss 1, Pp 141-155 (2012)
The aim of this study was to assess the clinical sensitivities of the tumor markers chromogranin A (CgA), urinary 5-hydroxyindoleacetic acid (5-HIAA) and alkaline phosphatase (AP) in neuroendocrine tumors (NETs) of the GastroEnteroPancreatic-(GEP-) s
Externí odkaz:
https://doaj.org/article/2408cbdb707b4fda9c36c09317d06a02
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol 2009, Iss default, Pp 1-10 (2009)
Thomas Strack1, Luc Martinez2, Stefano Del Prato3, Larry Blonde4, Burkhard Göke5, Vincent Woo6, Ann Millward7, Ramon Gomis8, Bill Canovatchel1, David Lawrence1, Nick Freemantle9 on behalf of the EXPERIENCE Trial Team1Pfizer Inc., New York, NY, USA;
Externí odkaz:
https://doaj.org/article/4ba2d7f98161403896fb0539e2d789f8
Autor:
Fabian Schnitzler, Matthias Friedrich, Christiane Wolf, Johannes Stallhofer, Marianne Angelberger, Julia Diegelmann, Torsten Olszak, Cornelia Tillack, Florian Beigel, Burkhard Göke, Jürgen Glas, Peter Lohse, Stephan Brand
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0116044 (2015)
A previous study suggested an association of the single nucleotide polymorphism (SNP) rs72796353 (IVS4+10 A>C) in the NOD2 gene with susceptibility to Crohn's disease (CD). However, this finding has not been confirmed. Given that NOD2 variants still
Externí odkaz:
https://doaj.org/article/921afa03548a4421a5bd042ff3838452
Autor:
Svenja Nölting, Julian Maurer, Gerald Spöttl, Elke Tatjana Aristizabal Prada, Clemens Reuther, Karen Young, Márta Korbonits, Burkhard Göke, Ashley Grossman, Christoph J Auernhammer
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143830 (2015)
The mTORC1-inhibitor everolimus shows limited efficacy in treating patients with gastro-entero-pancreatic or pulmonary neuroendocrine tumors (NETs), and poor outcome in patients with malignant pheochromocytoma or hepatic carcinoma. We speculated that
Externí odkaz:
https://doaj.org/article/7ceee008dd6a4c06a10157da84b0f126
Autor:
Fabian Schnitzler, Matthias Friedrich, Johannes Stallhofer, Ulf Schönermarck, Michael Fischereder, Antje Habicht, Nazanin Karbalai, Christiane Wolf, Marianne Angelberger, Torsten Olszak, Florian Beigel, Cornelia Tillack, Burkhard Göke, Reinhart Zachoval, Gerald Denk, Markus Guba, Christian Rust, Norbert Grüner, Stephan Brand
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135807 (2015)
Currently, limited data of the outcome of inflammatory bowel disease (IBD) in patients after solid organ transplantation (SOT) are available. We aimed to analyze effects of SOT on the IBD course in a large IBD patient cohort.Clinical data from 1537 I
Externí odkaz:
https://doaj.org/article/17857d0e37e44ee890fdf82c5e5136d6
Autor:
Florian Beigel, Matthias Friedrich, Corina Probst, Karl Sotlar, Burkhard Göke, Julia Diegelmann, Stephan Brand
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93498 (2014)
OBJECTIVE: Oncostatin M (OSM) is produced by activated T cells, monocytes, and dendritic cells and signals through two distinct receptor complexes consisting of gp130 and LIFR (I) or OSMR-β and gp130 (II), respectively. Aim of this study was to anal
Externí odkaz:
https://doaj.org/article/6b1939d04152422d886e9adb234488f8
Autor:
Fabian Schnitzler, Matthias Friedrich, Christiane Wolf, Marianne Angelberger, Julia Diegelmann, Torsten Olszak, Florian Beigel, Cornelia Tillack, Johannes Stallhofer, Burkhard Göke, Jürgen Glas, Peter Lohse, Stephan Brand
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e108503 (2014)
Very recently, a sub-analysis of genome-wide association scans revealed that the non-coding single nucleotide polymorphism (SNP) rs12212067 in the FOXO3A gene is associated with a milder course of Crohn's disease (CD) (Cell 2013;155:57-69). The aim o
Externí odkaz:
https://doaj.org/article/1695bec1287a460dbfdd41461a1f2b52
Autor:
Florian Beigel, Matthias Deml, Fabian Schnitzler, Simone Breiteneicher, Burkhard Göke, Thomas Ochsenkühn, Stephan Brand
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99293 (2014)
Mucosal healing (MH) is an important treatment goal in patients with inflammatory bowel disease (IBD), but factors predicting MH under medical therapy are largely unknown. In this study, we aimed to characterize predictive factors for MH in anti-TNF-
Externí odkaz:
https://doaj.org/article/ab475dad77794362957be955ab5134c4
Autor:
Eike Gallmeier, Dominik C Bader, Lydia Kriegl, Sabina Berezowska, Hendrik Seeliger, Burkhard Göke, Thomas Kirchner, Christiane Bruns, Enrico N De Toni
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56760 (2013)
IntroductionAgonistic antibodies targeting TRAIL-receptors 1 and 2 (TRAIL-R1 and TRAIL-R2) are being developed as a novel therapeutic approach in cancer therapy including pancreatic cancer. However, the cellular distribution of these receptors in pri
Externí odkaz:
https://doaj.org/article/e4473de467944c5199b82dfe358e786b
Autor:
Julia Diegelmann, Darina Czamara, Emmanuelle Le Bras, Eva Zimmermann, Torsten Olszak, Andrea Bedynek, Burkhard Göke, Andre Franke, Jürgen Glas, Stephan Brand
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e77773 (2013)
ObjectivesDMBT is an antibacterial pattern recognition and scavenger receptor. In this study, we analyzed the role of DMBT1 single nucleotide polymorphisms (SNPs) regarding inflammatory bowel disease (IBD) susceptibility and examined their functional
Externí odkaz:
https://doaj.org/article/c33b4fcd095842d982dc5b509339a64f