Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Burkhard, Schlosshauer"'
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86740 (2014)
In the field of regenerative medicine we aim to develop implant matrices for specific tissue needs. By combining two per se, cell-permissive gel systems with enzymatic crosslinkers (gelatin/transglutaminase and fibrinogen/thrombin) to generate a blen
Externí odkaz:
https://doaj.org/article/00ddbcb3a16d478685292aba7cf09baa
Publikováno v:
Cell Transplantation, Vol 17 (2008)
The quantity of therapeutic gene products released from genetically engineered cells can be controlled externally at different levels. The widely used approach of controlling expression, however, generally has the disadvantage that chemical substance
Externí odkaz:
https://doaj.org/article/3c9eb99bd1da4d718822e89e371b94fa
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 11:2699-2709
To improve the clinical performance of vascular prostheses, which is inacceptably low for implants with small diameters ( 10 000 hybridoma clones were generated. Screening with various deletion mutants of VEGFR-2, 49 highly-specific monoclonal antibo
Autor:
Dieter Stoll, Martin Dauner, Michael Doser, Burkhard Schlosshauer, Ursula Mittnacht, Susanne Hossfeld, Hanna Hartmann, Rumen Krastev, Ana Paula Pêgo
Publikováno v:
Journal of Controlled Release. 168:289-297
Binding, stabilizing and promoting cellular uptake of siRNA are all critical efforts in creating matrices for the localized delivery of siRNA molecules to target cells. In this study, we describe the generation of chitosan imidazole/siRNA nanoplexes
Autor:
Burkhard Schlosshauer, Reiner Hajosch, Nadine Hoffmann, Sven Dr. Oberhoffner, Susanne Nichterwitz
Publikováno v:
Neuroscience Letters. 484:118-122
Nerve guide implants approved for human application in the peripheral nervous system generally fail to bridge lesion gaps longer than 2 cm and cannot match the clinical performance of autologous nerve transplants. Since current synthetic implants are
Autor:
Steffen Dr. Oesser, Klaus Flechsenhar, Burkhard Schlosshauer, M. Suckfuell, Michael Ahlers, Reiner Hajosch
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. :372-379
To more effectively manage the substantial bleeding encountered during surgical procedures in oto-rhino-laryngology, we developed a novel hemostatic sponge made of pharmaceutical grade, chemically cross-linked gelatin. The sponge is characterized by
Publikováno v:
Journal of Neuroscience Methods. 189:205-209
A novel epineural tube implantation paradigm in the adult rat was designed for the analysis of regulatory cell interactions in peripheral nerves and for the development of therapeutic implants. The aim was to allow the integration of synthetic regene
Publikováno v:
European Journal of Cell Biology. 88:285-300
In order to reveal non-neuronal cell interactions after peripheral nerve lesions, we began to analyze the impact of sciatic nerve fibroblasts on Schwann cells in vitro. Both cell types are considered to have opposite effects on axonal regeneration. F
Publikováno v:
Cell Transplantation, Vol 17 (2008)
The quantity of therapeutic gene products released from genetically engineered cells can be controlled externally at different levels. The widely used approach of controlling expression, however, generally has the disadvantage that chemical substance
Publikováno v:
Biomaterials. 28:5536-5543
To overcome limitations on regeneration in the nervous system and other organs caused by insufficient blood supply, we have developed a gelatin sponge material which stimulates blood vessel formation, i.e. angiogenesis. Controlled chemical cross-link