Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Burkhard, Kneitz"'
Autor:
Abdallah Gaballa, Anneli Gebhardt-Wolf, Bastian Krenz, Greta Mattavelli, Mara John, Giacomo Cossa, Silvia Andreani, Christina Schülein-Völk, Francisco Montesinos, Raphael Vidal, Carolin Kastner, Carsten P. Ade, Burkhard Kneitz, Georg Gasteiger, Peter Gallant, Mathias Rosenfeldt, Angela Riedel, Martin Eilers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract In pancreatic ductal adenocarcinoma (PDAC), endogenous MYC is required for S-phase progression and escape from immune surveillance. Here we show that MYC in PDAC cells is needed for the recruitment of the PAF1c transcription elongation compl
Externí odkaz:
https://doaj.org/article/8a9d10af203b42eb8a6cbb3a3a12d74d
Autor:
Mirjam Kiener, Lanpeng Chen, Markus Krebs, Joël Grosjean, Irena Klima, Charis Kalogirou, Hubertus Riedmiller, Burkhard Kneitz, George N. Thalmann, Ewa Snaar-Jagalska, Martin Spahn, Marianna Kruithof-de Julio, Eugenio Zoni
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-17 (2019)
Abstract Background Despite latest advances in prostate cancer (PCa) therapy, PCa remains the third-leading cause of cancer-related death in European men. Dysregulation of microRNAs (miRNAs), small non-coding RNA molecules with gene expression regula
Externí odkaz:
https://doaj.org/article/42994b111bb84267b938f325eaf3f4be
Autor:
Brecht Chys, Gaëtan Devos, Wouter Everaerts, Maarten Albersen, Lisa Moris, Frank Claessens, Gert De Meerleer, Karin Haustermans, Alberto Briganti, Piotr Chlosta, Paolo Gontero, Markus Graefen, Christian Gratzke, R. Jeffrey Karnes, Burkhard Kneitz, Giansilvio Marchioro, Rafael Sanchez Salas, Martin Spahn, Bertrand Tombal, Henk Van Der Poel, Jochen Walz, Hendrik Van Poppel, Steven Joniau
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Cancer-specific survival (CSS) within high-risk non-metastatic prostate cancer varies dramatically. It is likely that within this heterogenous population there are subgroup(s) at extraordinary risk, burdened with an exaptational poor prog
Externí odkaz:
https://doaj.org/article/9841fc2cb1e04052996b03f921b2db0a
Autor:
Giancarlo Marra, Marco Oderda, Giorgio Calleris, Alessandro Marquis, Federica Peretti, Andrea Zitella, Marco Moschini, Rafael Sanchez-Salas, Robert Jeffrey Karnes, Burkhard Kneitz, Martin Spahn, Donatella Pacchioni, Paolo Gontero
Publikováno v:
Translational Andrology and Urology. 11:1271-1281
Currently, no biomarkers are able to differentiate lethal from relatively indolent prostate cancer (PCa) within high-risk diseases. Nonetheless, several molecules are under investigation. Amongst them, topoisomerase-II-alpha (We included 64 consecuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664fa60e71b28fb97d05ddd61e8c463a
https://doi.org/10.21037/tau-21-628
https://doi.org/10.21037/tau-21-628
Autor:
Martin Spahn, Hubertus Riedmiller, Manfred Gessler, Philipp Ströbel, Claus Jürgen Scholz, Susanne Kneitz, Evelyne Lerut, Hein van Poppel, Steven Joniau, Maria Schubert, Charis Kalogirou, Markus Krebs, Burkhard Kneitz
PDF file - 61K, Interferon signaling pathway and Enriched pathways based on lists of down-regulated or up-regulated genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4aa98ad4f36308ff6e4d1b3e7e6fc2
https://doi.org/10.1158/0008-5472.22401468
https://doi.org/10.1158/0008-5472.22401468
Autor:
Martin Spahn, Hubertus Riedmiller, Manfred Gessler, Philipp Ströbel, Claus Jürgen Scholz, Susanne Kneitz, Evelyne Lerut, Hein van Poppel, Steven Joniau, Maria Schubert, Charis Kalogirou, Markus Krebs, Burkhard Kneitz
XLSX file - 90K, List of up and downregulated genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fd6194b85b002b896f476011c06faf
https://doi.org/10.1158/0008-5472.22401447.v1
https://doi.org/10.1158/0008-5472.22401447.v1
Autor:
Martin Spahn, Hubertus Riedmiller, Manfred Gessler, Philipp Ströbel, Claus Jürgen Scholz, Susanne Kneitz, Evelyne Lerut, Hein van Poppel, Steven Joniau, Maria Schubert, Charis Kalogirou, Markus Krebs, Burkhard Kneitz
PDF file - 229K, Scatter- and Box blots show the expression of miR-221 in the study- and validation cohort in relation to clinical/histopathological parameters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21f2dd2092a7a380b4edd20b48b0756
https://doi.org/10.1158/0008-5472.22401477
https://doi.org/10.1158/0008-5472.22401477
Autor:
Martin Spahn, Hubertus Riedmiller, Manfred Gessler, Philipp Ströbel, Claus Jürgen Scholz, Susanne Kneitz, Evelyne Lerut, Hein van Poppel, Steven Joniau, Maria Schubert, Charis Kalogirou, Markus Krebs, Burkhard Kneitz
PDF file - 27K, Flow charts demonstrating the patient selection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a31afa89f96126c94a6f8229c719c91
https://doi.org/10.1158/0008-5472.22401480
https://doi.org/10.1158/0008-5472.22401480
Autor:
Martin Spahn, Hubertus Riedmiller, Manfred Gessler, Philipp Ströbel, Claus Jürgen Scholz, Susanne Kneitz, Evelyne Lerut, Hein van Poppel, Steven Joniau, Maria Schubert, Charis Kalogirou, Markus Krebs, Burkhard Kneitz
PDF file - 84K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8752b3951179b68d6f76a2a5535d24d5
https://doi.org/10.1158/0008-5472.22401456.v1
https://doi.org/10.1158/0008-5472.22401456.v1
Autor:
Martin Spahn, Hubertus Riedmiller, Manfred Gessler, Philipp Ströbel, Claus Jürgen Scholz, Susanne Kneitz, Evelyne Lerut, Hein van Poppel, Steven Joniau, Maria Schubert, Charis Kalogirou, Markus Krebs, Burkhard Kneitz
PDF file - 220K, MiR-221 down-regulation predicts clinical failure (CF) in high-risk prostate cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f33c5d2a7a13715e999553ba5192b88
https://doi.org/10.1158/0008-5472.22401474.v1
https://doi.org/10.1158/0008-5472.22401474.v1