Estradiol dimer inhibits tubulin polymerization and microtubule dynamics

Autor: Jurášek, Michal, Černohorská, Markéta, Řehulka, Jiří, Spiwok, Vojtěch, Sulimenko, Tetyana, Dráberová, Eduarda, Darmostuk, Maria, Gurská, Soňa, Frydrych, Ivo, Buriánová, Renata, Ruml, Tomáš, Hajdúch, Marián, Bartůněk, Petr, Dráber, Pavel, Džubák, Petr, Drašar, Pavel B., Sedlák, David

Publikováno v: In Journal of Steroid Biochemistry and Molecular Biology October 2018 183:68-79

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Triterpenoid phthalimides as selective anti-cancer agents targeting mitochondrial apoptosis.

Autor: Kazakova A; Department of Organic Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 1192/12, 779 00, Olomouc, Czech Republic., Frydrych I; Laboratory of Experimental Medicine, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Hněvotínská 1333/5, 779 00, Olomouc, Czech Republic., Jakubcová N; Department of Organic Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 1192/12, 779 00, Olomouc, Czech Republic; Laboratory of Medicinal and Organic Chemistry, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hněvotínská 1333/5, 779 00, Olomouc, Czech Republic., Pokorný J; Department of Organic Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 1192/12, 779 00, Olomouc, Czech Republic; Laboratory of Medicinal and Organic Chemistry, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hněvotínská 1333/5, 779 00, Olomouc, Czech Republic., Lišková B; Laboratory of Experimental Medicine, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Hněvotínská 1333/5, 779 00, Olomouc, Czech Republic., Gurská S; Laboratory of Experimental Medicine, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Hněvotínská 1333/5, 779 00, Olomouc, Czech Republic., Buriánová R; Laboratory of Experimental Medicine, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Hněvotínská 1333/5, 779 00, Olomouc, Czech Republic., Přibylka A; Department of Organic Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 1192/12, 779 00, Olomouc, Czech Republic., Džubák P; Laboratory of Experimental Medicine, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Hněvotínská 1333/5, 779 00, Olomouc, Czech Republic., Hajdúch M; Laboratory of Experimental Medicine, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Hněvotínská 1333/5, 779 00, Olomouc, Czech Republic., Urban M; Laboratory of Medicinal and Organic Chemistry, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hněvotínská 1333/5, 779 00, Olomouc, Czech Republic. Electronic address: milan.urban@upol.cz.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2024 Dec 10; Vol. 283, pp. 117126. Date of Electronic Publication: 2024 Dec 10.