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pro vyhledávání: '"Burhan Knouzy"'
Autor:
Agnès Duplany, Burhan Knouzy, Bernard Ferrier, Guy Martin, Maha El Hage, Catherine Gauthier, Gabriel Baverel
Publikováno v:
Xenobiotica. 43:54-62
1.Unlike cell lines and primary cells in culture, precision-cut tissue slices remain metabolically differentiated for at least 24-48 h and allow to study the effect of xenobiotics during short-term and long-term incubations. 2.In this article, we ill
Publikováno v:
Toxicology in Vitro. 24:99-107
Chloroacetaldehyde, one of the main products of hepatic ifosfamide metabolism, contributes to its nephrotoxicity. However, the pathophysiology of this toxicity is not fully understood. The present work examined the time and dose effects of clinically
Publikováno v:
Journal of applied toxicology : JAT. 30(3)
Chloroacetaldehyde (CAA), a product of hepatic metabolism of the widely used anticancer drug ifosfamide (IFO), has been reported to decrease cancer cell proliferation. The basis of this effect is not completely known but has been attributed to a drop