Super lattice formation of an array of volatile wetting droplets

Autor: Burghaus, R.

For an ordered array of critical volatile wetting droplets the formation of a super lattice by an Ostwald-ripening like competition process is considered. The underlying diffusion problem is treated within a quasistatic approximation and to first ord

Externí odkaz: http://arxiv.org/abs/cond-mat/9911468

Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.

Autor: Frechen S; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Ince I; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Dallmann A; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Gerisch M; DMPK, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Jungmann NA; DMPK, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Becker C; Clinical Pharmacology, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Lobmeyer M; Clinical Pharmacology, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Trujillo ME; Merck & Co., Inc., Rahway, New Jersey, USA., Xu S; Merck & Co., Inc., Rahway, New Jersey, USA., Burghaus R; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Meyer M; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.

Publikováno v: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Jan; Vol. 13 (1), pp. 79-92. Date of Electronic Publication: 2023 Oct 12.

Baseline clusters and the response to positive airway pressure treatment in obstructive sleep apnoea patients: longitudinal data from the European Sleep Apnea Database cohort.

Autor: Yassen A; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.; Joint first authors., Coboeken K; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.; Joint first authors., Bailly S; University Grenoble Alpes, Inserm, CHU Grenoble Alpes, Grenoble, France., Burghaus R; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Buskova J; National Institute of Mental Health, Klecany, Czech Republic., Dogas Z; Department of Neuroscience, Sleep Medicine Center, University of Split School of Medicine, Split, Croatia., Drummond M; Sleep and Non-Invasive Ventilation Unit of University Hospital São João, Medicine Faculty of Porto, Porto, Portugal., Gouveris H; ENT Department at Mainz University Hospital, Mainz, Germany., Joppa P; Department of Respiratory Medicine and Tuberculosis, Faculty of Medicine, P.J. Safarik University and L. Pasteur University Hospital, Kosice, Slovakia., Lippert J; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Lombardi C; Istituto Auxologico Italiano IRCCS, Sleep Disorders Center, San Luca Hospital, Milan, Italy.; Departmed of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Mihaicuta S; Centre for Research and Innovation in Precision Medicine of Respiratory Diseases, Department of Pulmonology, 'Victor Babes' University of Medicine and Pharmacy, CardioPrevent Foundation, Timisoara, Romania., Pépin JL; University Grenoble Alpes, Inserm, CHU Grenoble Alpes, Grenoble, France., Zou D; Department of Internal Medicine and Clinical Nutrition, Center for Sleep and Wake Disorders, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Hedner J; Department of Internal Medicine and Clinical Nutrition, Center for Sleep and Wake Disorders, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Pulmonary Medicine, Sleep Disorders Center, Sahlgrenska University Hospital, Gothenburg, Sweden.; Joint senior authors., Grote L; Department of Internal Medicine and Clinical Nutrition, Center for Sleep and Wake Disorders, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Pulmonary Medicine, Sleep Disorders Center, Sahlgrenska University Hospital, Gothenburg, Sweden.; Joint first authors.

Publikováno v: ERJ open research [ERJ Open Res] 2022 Oct 31; Vol. 8 (4). Date of Electronic Publication: 2022 Oct 31 (Print Publication: 2022).

Good Practices in Model-Informed Drug Discovery and Development: Practice, Application, and Documentation.

Autor: Marshall, SF¹ scott.marshall@pfizer.com, Burghaus, R², Cosson, V³, Cheung, SYA⁴, Chenel, M⁵, DellaPasqua, O⁶, Frey, N³, Hamrén, B⁷, Harnisch, L¹, Ivanow, F⁸, Kerbusch, T⁹, Lippert, J², Milligan, PA¹, Rohou, S¹⁰, Staab, A¹¹, Steimer, JL¹², Tornøe, C¹³, Visser, SAG¹⁴

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology. Mar2016, Vol. 5 Issue 3, p93-122. 30p.

Early prediction of decompensation (EPOD) score: Non-invasive determination of cirrhosis decompensation risk.

Autor: Schneider ARP; Institute of Applied Microbiology - iAMB, Aachen Biology and Biotechnology - ABBt, RWTH Aachen University, Aachen, Germany.; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany., Schneider CV; Division of Translational Medicine and Human Genetics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Genetics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Schneider KM; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Baier V; Institute of Applied Microbiology - iAMB, Aachen Biology and Biotechnology - ABBt, RWTH Aachen University, Aachen, Germany., Schaper S; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany., Diedrich C; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany., Coboeken K; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany., Mayer H; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany., Gu W; Medical Department I, Frankfurt University Hospital, Leverkusen, Germany., Trebicka J; Medical Department I, Frankfurt University Hospital, Leverkusen, Germany.; European Foundation for Study of Chronic Liver Failure, Barcelona, Spain., Blank LM; Institute of Applied Microbiology - iAMB, Aachen Biology and Biotechnology - ABBt, RWTH Aachen University, Aachen, Germany., Burghaus R; Clinical Pharmacometrics, Bayer AG, Wuppertal, Germany., Lippert J; Clinical Pharmacometrics, Bayer AG, Wuppertal, Germany., Rader DJ; Division of Translational Medicine and Human Genetics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Genetics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Thaiss CA; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Schlender JF; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany., Trautwein C; Department of Medicine III, University Hospital Aachen, Aachen, Germany., Kuepfer L; Institute for Systems Medicine, University Hospital RWTH Aachen, Aachen, Germany.

Publikováno v: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2022 Mar; Vol. 42 (3), pp. 640-650. Date of Electronic Publication: 2022 Feb 03.