Výsledky vyhledávání

Akademický článek

Mass Spectrometry Quantification of Anticancer Drug Uptake in Single Multicellular Tumor Spheroids.

Autor: Peng Z; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Lan Y; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Nimmo SL; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73117, United States., Bui RH; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73117, United States.; Department of Obstetrics & Gynecology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, United States., Benbrook DM; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, United States.; Department of Obstetrics & Gynecology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, United States.; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73117, United States., Burgett AWG; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, United States.; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73117, United States., Yang Z; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, United States.

Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2024 Sep 30; Vol. 7 (10), pp. 3011-3016. Date of Electronic Publication: 2024 Sep 30 (Print Publication: 2024).

Zobrazit plný text záznamu

Report

Inhibition of the Cellular Deubiquitinase UCHL1 Suppresses SARS-CoV-2 Replication.

Autor: Subramaniyan B; University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma., Larabee JL; University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma., Bodas M; University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma., Moore AR; University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma., Burgett AWG; University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma., Papin JF; University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma., Walters MS; University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma.

Publikováno v: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2023 Sep; Vol. 69 (3), pp. 367-370.

Zobrazit plný text záznamu

Akademický článek

Structure-Activity Relationships of Ligand Binding to Oxysterol-Binding Protein (OSBP) and OSBP-Related Protein 4.

Autor: Severance ZC; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73117, United States., Nuñez JI; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Le-McClain AT; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Malinky CA; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Bensen RC; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Fogle RS; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73117, United States., Manginelli GW; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Sakers SH; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Falcon EC; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73117, United States., Bui RH; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73117, United States., Snead KJ; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Bourne CR; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Burgett AWG; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73117, United States.; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2023 Mar 23; Vol. 66 (6), pp. 3866-3875. Date of Electronic Publication: 2023 Mar 14.

Zobrazit plný text záznamu

Akademický článek

Characterization of the SARS-CoV-2 Host Response in Primary Human Airway Epithelial Cells from Aged Individuals.

Autor: Subramaniyan B; Department of Medicine, Section of Pulmonary, Critical Care & Sleep Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Larabee JL; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Bodas M; Department of Medicine, Section of Pulmonary, Critical Care & Sleep Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Moore AR; Department of Medicine, Section of Pulmonary, Critical Care & Sleep Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Burgett AWG; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Myers DA; Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Georgescu C; Genes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA., Wren JD; Genes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA., Papin JF; Department of Pathology, Division of Comparative Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Walters MS; Department of Medicine, Section of Pulmonary, Critical Care & Sleep Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

Publikováno v: Viruses [Viruses] 2021 Aug 12; Vol. 13 (8). Date of Electronic Publication: 2021 Aug 12.

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Small Molecule Targeting of Oxysterol-Binding Protein (OSBP)-Related Protein 4 and OSBP Inhibits Ovarian Cancer Cell Proliferation in Monolayer and Spheroid Cell Models.

Autor: Bensen RC; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Gunay G; Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma 73019, United States., Finneran MC; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States., Jhingan I; Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma 73019, United States., Acar H; Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma 73019, United States.; Stephenson Cancer Center, University of Oklahoma, Oklahoma City, Oklahoma 73104, United States., Burgett AWG; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73117, United States.; Stephenson Cancer Center, University of Oklahoma, Oklahoma City, Oklahoma 73104, United States.

Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2021 Feb 04; Vol. 4 (2), pp. 744-756. Date of Electronic Publication: 2021 Feb 04 (Print Publication: 2021).

Zobrazit plný text záznamu

Akademický článek

Single Cell Mass Spectrometry Quantification of Anticancer Drugs: Proof of Concept in Cancer Patients.

Autor: Bensen RC; Department of Chemistry & Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma 73019, United States., Standke SJ; Department of Chemistry & Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma 73019, United States., Colby DH; Department of Chemistry & Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma 73019, United States., Kothapalli NR; Department of Chemistry & Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma 73019, United States., Le-McClain AT; Department of Chemistry & Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma 73019, United States., Patten MA; Oklahoma Biological Survey, University of Oklahoma, 111 E. Chesapeake Street, Norman, Oklahoma 73019, United States., Tripathi A; Stephenson Cancer Center, Section of Hematology Oncology, University of Oklahoma Health Sciences Center; 800 NE 10th Street, Oklahoma City, Oklahoma 73104, United States., Heinlen JE; Department of Urology, University of Oklahoma Health Sciences Center, 920 Stanton L. Young Boulevard, Oklahoma City, Oklahoma 73104, United States., Yang Z; Department of Chemistry & Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma 73019, United States., Burgett AWG; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, 1110 N. Stonewall Avenue, Oklahoma City, Oklahoma 73117, United States.

Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2021 Jan 05; Vol. 4 (1), pp. 96-100. Date of Electronic Publication: 2021 Jan 05 (Print Publication: 2021).

Zobrazit plný text záznamu

Akademický článek

Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site.

Autor: Terzyan SS; Laboratory of Biomolecular Structure and Function, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Nguyen LT; Department of Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, New York, USA., Burgett AWG; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Heroux A; Energy Sciences Directorate/Photon Science Division, Brookhaven National Laboratory, Upton, New York, USA., Smith CA; Stanford Synchrotron Radiation Lightsource, Stanford University, Menlo Park, California, USA., You Y; Department of Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, New York, USA., Hanigan MH; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA. Electronic address: marie-hanigan@ouhsc.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100066. Date of Electronic Publication: 2020 Nov 22.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání