Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Burgess JK"'
Autor:
Weckmann, M, Bahmer, T, Sand, JM, Rank Rønnow, S, Pech, M, Vermeulen, C, Faiz, A, Leeming, DJ, Karsdal, MA, Lunding, L, Oliver, BGG, Wegmann, M, Ulrich-Merzenich, G, Juergens, UR, Duhn, J, Laumonnier, Y, Danov, O, Sewald, K, Zissler, U, Jonker, M, König, I, Hansen, G, von Mutius, E, Fuchs, O, Dittrich, A-M, Schaub, B, Happle, C, Rabe, KF, van de Berge, M, Burgess, JK, Kopp, MV, ALLIANCE Study Group as part of the German Centre for Lung Research (DZL)
BACKGROUND: Asthma is a heterogeneous syndrome substantiating the urgent requirement for endotype-specific biomarkers. Dysbalance of fibrosis and fibrolysis in asthmatic lung tissue leads to reduced levels of the inflammation-protective collagen 4 (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::25c5e1e4b6c48fc3da58fef357bd7fdc
https://hdl.handle.net/10453/155572
https://hdl.handle.net/10453/155572
Autor:
Zuo H, Faiz A, van den Berge M, Mudiyanselage SNHR, Borghuis T, Timens W, Nikolaev VO, Burgess JK, Schmidt M
Cigarette smoke (CS), a highly complex mixture containing more than 4000 compounds, causes aberrant cell responses leading to tissue damage around the airways and alveoli which underlies various lung diseases. Phosphodiesterases (PDEs) are a family o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::0d484e1060672cf85c392ca46675fe49
https://hdl.handle.net/10453/143847
https://hdl.handle.net/10453/143847
Autor:
Liu, G, Cooley, MA, Jarnicki, AG, Borghuis, T, Nair, PM, Tjin, G, Hsu, AC, Haw, TJ, Fricker, M, Harrison, CL, Jones, B, Hansbro, NG, Wark, PA, Horvat, JC, Scott Argraves, W, Oliver, BG, Knight, DA, Burgess, JK, Hansbro, PM
Copyright: © 2019, American Society for Clinical Investigation. Tissue remodeling/fibrosis is a major feature of all fibrotic diseases, including idiopathic pulmonary fibrosis (IPF). It is underpinned by accumulating extracellular matrix (ECM) prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::362506b0d155b11be4ee584aa9ef0a1a
https://hdl.handle.net/10453/137003
https://hdl.handle.net/10453/137003
Autor:
Faiz, A, Weckmann, M, Tasena, H, Vermeulen, CJ, Van Den Berge, M, Ten Hacken, NHT, Halayko, AJ, Ward, JPT, Lee, TH, Tjin, G, Black, JL, Haghi, M, Xu, CJ, King, GG, Farah, CS, Oliver, BG, Heijink, IH, Burgess, JK
© ERS 2018. Chronic mucus hypersecretion (CMH) contributes to the morbidity and mortality of asthma, and remains uncontrolled by current therapies in the subset of patients with severe, steroidresistant disease. Altered cross-talk between airway epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::fe63120dc46bf4714fb633f140aa88ed
https://hdl.handle.net/10453/132427
https://hdl.handle.net/10453/132427
Autor:
Liu, G, Cooley, MA, Jarnicki, AG, Hsu, AC-Y, Nair, PM, Haw, TJ, Tjin, G, Jones, B, Harrison, CL, Fricker, M, Inman, MD, Walker, MM, Horvat, JC, Oliver, BG, Argraves, WS, Knight, DA, Burgess, JK, Hansbro, PM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::b91a18c0922f18ca41965ee8939256c9
https://hdl.handle.net/10453/154574
https://hdl.handle.net/10453/154574
& Sons Ltd and Foundation for Cellular and Molecular Medicine. Lymphangioleiomyomatosis (LAM) is associated with dysfunction of the tuberous sclerosis complex (TSC) leading to enhanced cell proliferation and migration. This study aims to examine whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::de6a4baf8ed38605396c906b42ba8858
https://hdl.handle.net/10453/41765
https://hdl.handle.net/10453/41765
Autor:
Jaffar J, Unger S, Corte TJ, Keller M, Wolters PJ, Richeldi L, Cerri S, Prêle CM, Hansbro PM, Argraves WS, Oliver RA, Oliver BG, Black JL, Burgess JK
Background The underlying mechanisms of idiopathic pulmonary fibrosis (IPF) are unknown. This progressive disease has high mortality rates and current models for prediction of mortality have limited value in identifying which patients will progress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::4461eaa38925191330066fcb776c65ba
https://hdl.handle.net/10453/146731
https://hdl.handle.net/10453/146731
Fibulin-1 (FBLN-1) is a secreted glycoprotein that is associated with extracellular matrix (ECM) formation and rebuilding. Abnormal and exaggerated deposition of ECM proteins is a hallmark of many fibrotic diseases, such as chronic obstructive pulmon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::a6a09ccd746e864b7553761b392a1e97
https://hdl.handle.net/10453/28524
https://hdl.handle.net/10453/28524
In terms of service work, teams tend to be more prevalent in call centres than in other service industries. While the literature highlights key debates surrounding the use of teams in call centres, most of it is drawn from studies on large call centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::6189784f1e7f044b3c4bab8c13dab159
https://hdl.handle.net/10453/27359
https://hdl.handle.net/10453/27359
β 2-agonists are now contraindicated as monotherapy for asthma, and increased PDE4D has been speculated to contribute to this phenomenon. In this study we investigated the expression of PDE4D in asthmatic and nonasthmatic ASM cells and its regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::bbece234dcb33a92462aec42e6062dc0
https://hdl.handle.net/10453/29763
https://hdl.handle.net/10453/29763